Game Time: 12:00 pm ET, Saturday, September 13, 2025
Venue: Saban Field at Bryant-Denny Stadium, Tuscaloosa, AL
Where to Watch: ABC
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Wisconsin +20.5, Alabama -20.5; Over/Under: 46.5 points
Bet365: Point Spread: Wisconsin +20.5, Alabama -20.5; Over/Under: 46.5 points
BetMGM: Point Spread: Wisconsin +20.5, Alabama -20.5; Over/Under: 46.5 points
Season Record
Wisconsin Badgers: 2-0 (0-0) (13th place, Big Ten)
Alabama Crimson Tide: 1-1 (0-0) (13th place, SEC)
Do not miss out on our expert handicapper analysis! ASA, Inc. is on a HOT STREAK in college football on a 4-0 CFB RUN for +$4,000 PROFIT! Make sure you check out his picks and many more from the expert handicappers featured in the Shop Picks section.
Recent Form
Wisconsin Badgers: won their last game at home against the Middle Tennessee Blue Raiders 42-10.
Alabama Crimson Tide: won their last game at home against the Louisiana-Monroe Warhawks 73-0.
Wisconsin Badgers vs Alabama Crimson Tide Preview and Analysis
Wisconsin is entering this game with a 2-0 record overall and they have a 0-0 record in their conference games too. They are 2-0 in their home games, 0-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against Middle Tennessee State 42-10. Danny O'Neil was the starting QB and he completed 23/27 passes for 283 passing yards, 3 touchdowns, and 1 interception. Trech Kekahuna led the team in rushing yards with 61 and 1 TD. Lance Mason led the receivers with 102 receiving yards on 7 receptions and 1 TD. Christian Alliegro led the defense in that game with 6 solo tackles and 1 assisted tackle while Sebastian Cheeks, Tackett Curtis, Tyreese Fearbry, and Brandon Lane each led the defense in sacks with 1. Omillio Agard came away with the only interception for them in that one.
Alabama is entering this game with a 1-1 record overall and they have a 0-0 record in their conference games too. They are 1-0 in their home games, 0-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against LA-Monroe 73-0. Ty Simpson was the starting QB and he completed 17/17 passes for 226 passing yards, 3 touchdowns, and 0 interceptions. AK Dear led the team in rushing yards with 76 and 1 TD. Germie Bernard led the receivers with 67 receiving yards on 3 receptions and 2 TDs. James Smith led the defense in that game with 4 solo tackles and 0 assisted tackles while no one on the team recorded a sack for them. Justin Jefferson came away with the only interception for them in that one.
Wisconsin vs Alabama Prediction
The current betting odds have Alabama listed as a 20.5 point favorite in this game according to Draftkings Sportsbook. Alabama hasn't looked great in their games this season with their 1-1 record overall. They lost their first game of the season on the road against Florida State and they git embarrassed in that one. They had nothing going for them in that game, but as bad as they looked in that one, it might not be a terrible loss with Florida State looking good again. Alabama also bounced back in their last game, beating Louisiana-Monroe at home 73-0. The offense looked a lot better in that one and the defense was much better too. They should play better being at home in this one and they still have a lot more talent on paper than Wisconsin has. Meanwhile, Wisconsin has looked good in their games this season with their 2-0 record overall. They haven't played any teams from the FCS, but they haven't really played any good opponents either. They just beat Middle Tennessee 42-10 in their last one, but they struggled to beat Miami-Ohio in week 1, winning that game 17-0, and both of those games were at home too. This is going to be their first road test of the season against a more talented opponent and Alabama is going to be playing the rest of the season with a chip on their shoulder after that opening loss. This is a good opportunity for Alabama to make a statement at home and get a much needed big win over a Big Ten opponent. The best way to place a bet here is on Alabama to cover the spread in this game.
Wisconsin Alabama Prediction: Our NCAAF Pick for Saturday, September 13, 2025 (12:00 pm ET start time) is Alabama 42 Wisconsin 17.
Don't miss our champion handicappers free picks and expert football picks today. And if you enjoyed this Wisconsin Badgers Alabama Crimson Tide prediction, be sure to drop by every day for our weekly NCAAF predictions and previews.
NCAAF Betting Trends
Wisconsin Badgers: 1-5 ATS as a road underdog of 14.5 to 21 points. 3-6 ATS in non-conference games. 1-3 ATS as a road underdog. 4-0 OVER as a road underdog. 9-5 OVER after playing a game at home.
Alabama Crimson Tide: 11-4 ATS in home lined games. 10-4 ATS as a home favorite. 11-5 ATS against Big 10 conference opponents. 8-4 OVER as a home favorite. 8-2 OVER when the total is between 42.5 and 49. 7-2 OVER after scoring 37 points or more last game.
Key Injuries
Wisconsin Badgers: B. Lemirand (WR) Questionable - Undisclosed. L. Emmerich (S) Questionable - Undisclosed. K. Heywood (OG) Questionable - Undisclosed. E. Van Dyn Hoven (LB) Questionable - Undisclosed. T. Ashcraft (TE) Questionable - Leg. C. Walker (LB) Questionable - Undisclosed. B. Edwards Jr. (QB) Questionable - Undisclosed. J. Renfro (OG) Questionable - Undisclosed. B. Nelson (OG) Questionable - Undisclosed.
Alabama Crimson Tide: R. Montgomery (OG) Questionable - Undisclosed. D. Lewis Jr. (TE) Questionable - Undisclosed. J. Latham (LB) Questionable - Undisclosed. T. Keenan III (DL) Questionable - Ankle. A. Hampton (WR) Questionable - Undisclosed. J. Miller (RB) Questionable - Collarbone. R. Williams (WR) Questionable - Concussion. J. Beaman (DL) Out - Lower Body.
Notable Quotes
"We had some tough conversations at halftime, really trying to flip the script. We knew that we weren't playing to our standard." - Danny O’Neil after his team’s win against MTSU in their last game.
"They made their minds up at some point leading up to (last) Sunday. Because by Sunday they were ready to roll, and that carried through the whole week. The challenge now is, can you sustain it?” - Kalen DeBoer after his team’s win against ULM in their last game.
Starting Lineups
Wisconsin Badgers
WR Anthony II, Vinny
WR Brooks Jr., Chris
WR Kekahuna, Trech
TE Mason, Lance
QB Edwards Jr., Billy
RB Jones, Dilin
Alabama Crimson Tide
WR Horton, Isaiah
WR Bernard, Germie
WR Williams, Ryan
TE Lewis Jr., Danny
TE Cuevas, Josh
QB Simpson, Ty
RB Young, Richard
Statistical Leaders
Wisconsin Badgers
Passing: D. O'Neil (403)
Rushing: D. Jones (109)
Receiving: V. Anthony II (107)
Touchdowns: V. Anthony II (2)
Alabama Crimson Tide
Passing: T. Simpson (480)
Rushing: K. Riley (100)
Receiving: G. Bernard (213)
Touchdowns: J. Cuevas (2)
Coaches:
Wisconsin Badgers: Luke Fickell (4th season)
Alabama Crimson Tide: Kalen DeBoer (2nd season)