by Rod Pearson
Monday, Oct 06, 2025
Game Time: 12:45 pm ET, Saturday, October 11, 2025
Venue: Vaught Hemingway Stadium, Oxford, MS
Where to Watch: SEC Network
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: WSU +32.5, Ole Miss -32.5; Over/Under: 58.5 points
Bet365: Point Spread: WSU +32.5, Ole Miss -32.5; Over/Under: 59 points
BetMGM: Point Spread: WSU +32.5, Ole Miss -32.5; Over/Under: 59.5 points
Season Record
Washington State Cougars: 3-2 (0-0) (1st place, Pac-12)
Mississippi Rebels: 5-0 (3-0) (1st place, SEC)
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Recent Form
Washington State Cougars: won their last game on the road against the Colorado State Rams 20-3.
Mississippi Rebels: won their last game at home against the LSU Tigers 24-19.
Washington State Cougars vs Mississippi Rebels Preview and Analysis
Washington State is entering this game with a 3-2 record overall and they have a 0-0 record in their conference games too. They are 2-1 in their home games, 1-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against Colorado State 20-3. Zevi Eckhaus was the starting QB and he completed 16/28 passes for 189 passing yards, 2 touchdowns, and 0 interceptions. Leo Pulalasi led the team in rushing yards with 50. Josh Meredith led the receivers with 60 receiving yards on 4 receptions. Anthony Palano led the defense in that game with 3 solo tackles and 10 assisted tackles while Nilasoni Finau led the defense in sacks with 2. No one on the defense came away with an interception for them in that one.
Ole Miss is entering this game with a 5-0 record overall and they have a 3-0 record in their conference games too. They are 4-0 in their home games, 1-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against LSU 24-19. Trinidad Chambliss was the starting QB and he completed 23/39 passes for 314 passing yards, 1 touchdown, and 1 interception. Kewan Lacy led the team in rushing yards with 87 and 1 TD. Cayden Lee led the receivers with 70 receiving yards on 4 receptions and 1 TD. Antonio Kite led the defense in that game with 4 solo tackles and 0 assisted tackles while William Echoles led the defense in sacks with 1. Wydett Williams Jr. came away with the only interception for them in that one.
Washington State vs Mississippi Prediction
The current betting odds have Ole Miss listed as a 32.5 point favorite in this game according to Draftkings Sportsbook. Ole Miss has looked great in their games this season with their 5-0 record overall and their 3-0 conference record which has them right at the top of the SEC. They are off a big win against a ranked LSU team in their last one and they are starting to emerge as a real contender in this conference early on. Their offense has been rolling in their games this season as it usually does, but their defense has also looked a lot better this season too. Meanwhile, Washington State has looked good in their games this season with their 3-2 record overall, but they haven't played many strong opponents to open up the season. They are off a 20-3 win over Colorado State in their last one which was their first road win of the season, but their only other road game this year was against North Texas and they lost 59-10. They also lost at home to Washington 59-24 and they simply don't have the talent on offense to keep up with these high power offenses. Ole Miss has a lot more talent on offense to bury this Washington State team and Wazzu won't be able to respond or get the stops needed on defense to keep themselves in this game. Ole Miss is also in a great situation for this game, being at home and coming out of a bye week with extra time to prepare. The best way to place a bet here is on Ole Miss to cover the spread in this game.
Washington State Mississippi Prediction: Our NCAAF Pick for Saturday, October 11, 2025 (12:45 pm ET start time) is Ole Miss 56 Wazzu 10.
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NCAAF Betting Trends
Washington State Cougars: 1-4 ATS as a road underdog of 28.5 to 35 points. 5-14 ATS on the road off a road win. 21-37 ATS on the road after playing their last game on the road. 41-26 UNDER vs. good passing teams averaging 8 or more passing yards/att. 14-7 UNDER on the road off an upset win as an underdog.
Mississippi Rebels: 19-10 ATS in all lined games. 10-5 ATS as a home favorite. 11-1 ATS in non-conference games. 5-1 ATS when playing against a good team (Win Pct. 60% to 75%). 17-9 UNDER as a favorite. 11-5 UNDER off a home win. 12-5 UNDER after playing a game at home.
Key Injuries
Washington State Cougars: H. Cedarland (TE) Questionable - Lower Body.
Mississippi Rebels: J. Saunders Jr. (S) Questionable - Undisclosed. D. Price (WR) Questionable - Undisclosed.
Notable Quotes
"We got to get better at situational awareness. We got to get better at tackling. We got to continue to work our feet in the line of scrimmage and running off the ball at o-line. We got to make sure that the communication is clean. We got to be able to win in the red zone. And then obviously just continue to work on the small things, whether it's winning a one-on-one matchup and making a hard contested play or defensively winning your one-on-one and not grabbing and not looking and not peeking. So, there's plenty of things that we'll see on this film that will be addressed and we'll move forward." - Jimmy Rogers on what his team needs to do to improve.
“It’s just a really cool story. A little short kid from Division II going against Nussmeier and the mighty Tigers of LSU. It was awesome.” - Lane Kiffin on Trinidad Chambliss after his team’s win against LSU in their last game.
Starting Lineups
Washington State Cougars
WR Noga, Jeremiah
WR Smithson, Leyton
WR Meredith, Joshua
TE Leckner, Trey
QB Potter, Jaxon
RB Johnson, Angel
Mississippi Rebels
WR Wallace III, Harrison
WR Stribling, De'Zhaun
WR Lee, Cayden
TE Hasz, Luke
QB Simmons, Austin
RB Lacy, Kewan
Statistical Leaders
Washington State Cougars
Passing: Jaxon Potter (604)
Rushing: Kirby Vorhees (156)
Receiving: Joshua Meredith (255)
Touchdowns: Zevi Eckhaus (2)
Mississippi Rebels
Passing: Trinidad Chambliss (1,033)
Rushing: Kewan Lacy (445)
Receiving: Harrison Wallace III (361)
Touchdowns: Kewan Lacy (8)
Coaches:
Washington State Cougars: Jimmy Rogers (1st season)
Mississippi Rebels: Lane Kiffin (6th season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
