UConn Huskies vs Duke Blue Devils Prediction, Picks and Game Preview - 03/29/2026

Game Time: 5:05 pm ET, Sunday, March 29, 2026

Venue:  Capital One Arena, Washington, DC

Where to Watch:  CBS

DraftKings:  Point Spread:  UConn +5.5, Duke -5.5; Over/Under:  133.5 points

Bet365:  Point Spread:  UConn +5.5, Duke -5.5; Over/Under:  133.5 points

BetMGM:  Point Spread:  UConn +5.5, Duke -5.5; Over/Under:  133.5 points

UConn Huskies:  32-5 (17-3) (2nd place, Big East)

Duke Blue Devils:  35-2 (17-1) (1st place, ACC)

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UConn Huskies:  4-1  last 5

Duke Blue Devils:  5-0  last 5

UConn is entering this game with a 32-5 record overall, a 17-3 record in conference games, and they are 8-1 in their neutral site games this season where they will be in this game. They are coming off a win against the Michigan State Spartans in their last game. Tarris Reed Jr. led the team in points in that game with 20 while Alex Karaban was next on the team with 17. Malachi Smith led the team in assists with 7 in that game while Alex Karaban led the team in rebounds with 7. They were 46.2% from the field, 42.9% from 3-point range, and 62.5% from the free throw line with their shooting in that game. Their offense is averaging 77.2 PPG and their defense is allowing their opponents to average 65 PPG against them. UConn has an ATS record of 15-22 this season and their O/U record is 18-19.

Duke is entering this game with a 35-2 record overall, a 17-1 conference record, and they are 10-1 in their neutral site games this season where they will be in this game. They are coming off a win against the St John’s Red Storm in their last game. Isaiah Evans led the team in points in that game with 25 while Cameron Boozer was next on the team with 22. Cameron Boozer, Cayden Boozer, and Dame Sarr each led the team in assists with 3 in that game while Cameron Boozer led the team in rebounds with 10. They were 53.6% from the field, 35.7% from 3-point range, and 62.5% from the free throw line with their shooting in that game. Their offense is averaging 81.9 PPG and their defense is allowing their opponents to average 63.4 PPG against them. Duke has an ATS record of 20-17 this season and their O/U record is 13-24.

The current betting odds have UConn listed as a 5.5 point underdog in this game according to Draftkings Sportsbook. UConn has looked really good in their games this season with their 32-5 record overall and their 17-3 conference record which had them right near the top of the Big East. They have looked great in their neutral site games too with their 8-1 record in those. Meanwhile, Duke has looked great in their games this season with their 35-2 record overall and their 17-1 conference record which had them right at the top of the ACC. They are also 10-1 in their neutral site games this year. Duke has been rolling all season and they have some really good wins under their belt. They have a win over Michigan and have beaten some of the top teams in the nation, but they definitely haven't been at their best lately. They are off a win over St John's in their last one, but they barely won that game by 5 points in the end and they were trailing for a lot of that game too. They are also the only ACC team remaining and their conference was weaker this season as the ACC teams haven't looked good in this tournament this year. UConn wasn't the best team in their conference this season as they were 2nd in the regular season and lost to St John's in the Big East Tournament, but they were still the higher seed in this tournament due to such a strong non-conference schedule. UConn has been tested and they have a really good coach who has won the National Championship twice in the last few years. Hurley is going to have his team ready for this game against a Duke team that looked shaky in the last round, and UConn has the talent to go toe-to-toe with Duke here. The best way to place a bet here is on UConn to cover the spread in this game. 

UConn Duke Prediction:  Our NCAAB Pick for Sunday, March 29, 2026 (5:05 pm ET start time) is UConn 72 Duke 67.

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UConn Huskies: 14-22 ATS in all games. 5-13 ATS after 3 or more consecutive wins. 13-20 ATS versus good ball handling teams - committing 14 turnovers/game or less. 7-1 UNDER in a neutral court game where the total is 130 to 139.5. 26-17 UNDER in non-conference games.

Duke Blue Devils: 29-17 ATS in non-conference games. 28-17 ATS versus very good teams - outscoring their opponents by 8+ points/game. 39-23 ATS versus good shooting teams - making 45% of their shots or more. 12-6 UNDER when the total is 130 to 139.5. 25-14 UNDER versus good rebounding teams - outrebounding opponents by 4+ per game.

UConn Huskies:  None.

Duke Blue Devils:  I. Ufochukwu (C) Out - Undisclosed. S. Wilkins (G-F) Out - Redshirt.

“He’s a calming influence for me. I’m waiting for you to laugh. It’s like having an associate head coach that is in the locker room, that lives in the apartments, that is in the dining, that is in the weight room, that’s peer pressuring his teammates to do extra. It’s like having a top assistant that’s on your team and always around your players.” - Dan Hurley after his team’s win against MSU in the Sweet 16 of the NCAA Tournament on Friday. 

“To be honest, he had no business playing tonight — 99 percent of guys do not come back to play under the circumstances of what’s happened to him. It was incredible the way he willed us.” - Jon Scheyer after his team’s win against St John’s in the NCAA Tournament Sweet 16 on Friday.

S. Ball 

S. Demary 

A. Karaban 

B. Mullins 

T. Reed

C. Boozer 

I. Evans 

C. Foster 

P. Ngongba 

D. Sarr

PPG: Tarris Reed Jr. (14.3)

APG: Silas Demary Jr. (6.1)

Reb/G: Tarris Reed Jr. (8.8)

PPG: Cameron Boozer (22.4)

APG: Cameron Boozer (4.1)

Reb/G: Cameron Boozer (10.3)

Coaches:

UConn Huskies: Dan Hurley (8th season)

Duke Blue Devils: Jon Scheyer (4th season)