UCLA Bruins vs Oregon Ducks Prediction, Picks and Game Preview - 10/10/2026

Game Time: 3:30 pm ET, Saturday, October 10, 2026

Venue:  Autzen Stadium, Eugene, OR

Where to Watch:  CBS

DraftKings:  Point Spread:  UCLA +11.5, Oregon -11.5; Over/Under:  57.5 points

Bet365:  Point Spread:  UCLA +11.5, Oregon -11.5; Over/Under:  57.5 points

BetMGM:  Point Spread:  UCLA +11.5, Oregon -11.5; Over/Under:  58.5 points

UCLA Bruins:  4-0 (2-0) (3rd place, Big Ten)

Oregon Ducks:  3-1 (1-0) (7th place, Big Ten)

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UCLA Bruins:  won their last game on the road against the Maryland Terrapins 54-3.

Oregon Ducks:  won their last game on the road against the USC Trojans 41-27.

UCLA is entering this game with a 4-0 record overall and they have a 2-0 record in their conference games too. They are 2-0 in their home games, 2-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against Maryland 54-3. Nico Iamaleava was the starting QB and he completed 15/24 passes for 209 passing yards, 1 touchdown, and 0 interceptions. Wayne Knight led the team in rushing yards with 100 and 1 TD. Aidan Mizell led the receivers with 83 receiving yards on 1 reception and 1 TD. Sammy Omosigho led the defense in that game with 7 tackles while Scott Taylor and Sahir West each led the defense in sacks with 1. Ta'Shawn James, Trent Hendrick, Mason Rivera, and Scooter Jackson each came away with 1 interception for them in that one.

 

 

 

Oregon is entering this game with a 3-1 record overall and they have a 1-0 record in their conference games too. They are 2-0 in their home games, 1-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against USC 41-27. Dante Moore was the starting QB and he completed 8/10 passes for 77 passing yards before leaving injured and getting replaced by Dylan Raiola who completed 19/25 passes for 289 yards, 2 touchdowns, and 0 interceptions. Jordon Davison led the team in rushing yards with 66 and 1 TD. Jamari Johnson led the receivers with 119 receiving yards on 7 receptions. Devon Jackson led the defense in that game with 10 tackles while Matayo Uiagalelei and Bear Alexander each led the defense in sacks with 1. Koi Perich came away with the only interception for them in that one.

The current betting odds have Oregon listed as an 11.5 point favorite in this game according to Draftkings Sportsbook. Oregon has looked good in their games this season with their 3-1 record overall and their 1-0 conference record which has them in the top half of the Big Ten. They have looked good on their home field too with their 2-0 home record this season. Meanwhile, UCLA has looked great in their games this season with their 4-0 record overall and their 2-0 conference record which has them right near the top of the Big Ten. They have been a good road team too with their 2-0 road record this year. UCLA has really turned things around this season with Bob Chesney in his 1st year coaching, but they still haven't been challenged yet with an easier schedule so far. They are coming off a 54-3 win over Maryland in their last one, but this is going to be their biggest challenge of the season so far. Oregon had a terrible start to the season as they looked really shaky against Boise State in their season opener and they ended up losing to Oklahoma State the next week. They have rebounded since then though and now they are coming off a 41-27 win over USC in their last one. They even lost their starting QB in that win to a scary looking injury, but they rallied around Raiola who looked great taking over and they have a ton of momentum on their side now as they are slowly putting the pieces back together. UCLA's turnaround to start the season has been a nice story, but they haven't really played anyone yet and this Oregon team still has tons of talent that could make them one of the best teams in the nation if they get rolling again. The best way to place a bet here is on Oregon to cover the spread in this game. 

UCLA Oregon Prediction:  Our NCAAF Pick for Saturday, October 10, 2026 (3:30 pm ET start time) is Oregon 42 UCLA 28.

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UCLA Bruins: 14-25 ATS on the road after a bye week. 19-28 ATS on the road after scoring 37 points or more last game. 13-22 ATS on the road against teams with a turnover margin of +1 per game or better. 60-42 OVER when playing against a top-level team (Win Pct. > 75%). 34-27 OVER against teams with a turnover margin of +1 per game or better.

Oregon Ducks: 28-19 ATS in a home game where the total is between 56.5 and 63. 66-38 ATS vs. good passing teams averaging 8 or more passing yards/att. 68-46 ATS when playing against a top-level team (Win Pct. > 75%). 24-11 OVER as a home favorite of 7.5 to 14 points. 30-17 OVER in a home game where the total is between 56.5 and 63.

UCLA Bruins:  M. Matthews (WR) Out - Undisclosed. T. Johnson (CB) Questionable - Undisclosed. J. Johnson (CB) Questionable - Undisclosed. S. Yoon (OG) Questionable - Undisclosed. A. Mizell (WR) Questionable - Undisclosed. T. Dieffenbach (QB) Questionable - Undisclosed. J. Phifer (TE) Questionable - Undisclosed.

Oregon Ducks:  D. Moore (QB) Questionable - Concussion. J. Lott (WR) Questionable - Hand. I. Hooks (WR) Questionable - Undisclosed. J. Johnson (TE) Questionable - Undisclosed. D. Gresham (WR) Questionable - Neck. S. Price (RB) Questionable - Undisclosed. K. Harrison (TE) Questionable - Undisclosed. J. McClellan (WR) Out - Foot.

"We need his best. You know, we need everybody's best, though, to be honest with you. It's not just any one guy. Obviously, a lot of it goes through him. He's done a phenomenal job up to this point in time of getting us into the right calls, handling his business the right way, protection, keeping himself safe, getting the ball out quickly, doing all the things he's got to be able to do. Today, he's got to be spot-on come Saturday. Day one—well, day two—of some of the new stuff, and he's done a really good job up to this point." - Bob Chesney on his team’s upcoming game against Oregon this week. 

“Certainly (there was) an energy change when Dante got hurt.” - Dan Lanning after his team’s win against USC in their last game. 

WR Rowe Jr., Brian

WR Ellis, Landon

WR Morgan, Semaj

TE Phifer, Josh

QB Iamaleava, Nico

RB Knight, Wayne

WR Moore, Dakorien

WR Hampton, Messiah

WR Stewart, Evan

TE Johnson, Jamari

QB Moore, Dante

RB Davison, Jordon

Passing: Nico Iamaleava (820)

Rushing: Wayne Knight (445)

Receiving: Semaj Morgan (174)

Touchdowns: Wayne Knight (9)

Passing: Dante Moore (926)

Rushing: Jordon Davison (260)

Receiving: Evan Stewart (278)

Touchdowns: Jordon Davison (5)

Coaches:

UCLA Bruins: Bob Chesney (1st season)

Oregon Ducks: Dan Lanning (5th season)