Toronto Blue Jays vs New York Yankees Prediction, Preview and Odds - 10/07/2025

Game Time: 8:08 pm ET, Tuesday, October 7, 2025

Venue:  Yankee Stadium, Bronx, NY

Where to Watch:  Fox Sports 1

DraftKings:  Moneyline odds:  Blue Jays +123, Yankees -148; Over/Under:  7.5 runs

Bet365:  Moneyline odds:  Blue Jays +125, Yankees -150; Over/Under:  7.5 runs

BetMGM:  Moneyline odds:  Blue Jays +125, Yankees -150; Over/Under:  7.5 runs

Toronto Blue Jays:  94-68 (1st place, AL East)

New York Yankees:  94-68 (2nd place, AL East)

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Toronto Blue Jays:  7-3 last 10

New York Yankees:  7-3 last 10

The Blue Jays are entering this series off a win and won their 3-game series against the Tampa Bay Rays 2-1 to end the regular season. They finished the regular season with a 94-68 record overall and had a road record of 40-41. This is the 3rd game of a best 3 out of 5 game series with the Yankees on Tuesday for the American League Division Series. The Blue Jays won the series opener on Saturday and the 2nd game of this series on Sunday. Their offense ranks 3rd in the MLB with a .760 OPS. Trey Yesavage was their starting pitcher on Sunday while Shane Bieber is making his start in this game on Tuesday. He is 4-2 with a 3.57 ERA this season. His team won 4 of their last 5 games this season with him making an appearance. In his last MLB start, he allowed 2 ER, 2 HR, and 2 BB with 3 Ks on 5 hits through 5 IP against the Tampa Bay Rays.

The Yankees are entering this series off a win and won their best of 3-game series against the Boston Red Sox 2-1 in the American League Wild Card Series. They finished the regular season with a 94-68 record overall and had a home record of 50-31. This is the 3rd game of a best 3 out of 5 game series with the Blue Jays on Tuesday for the ALDS. The Yankees lost the 1st game of this series on Saturday and the 2nd game on Sunday. Their offense ranks 1st in the MLB with a .787 OPS. Max Fried was their starting pitcher on Sunday while Carlos Rodón is making his start in this game on Tuesday. He is 18-9 with a 3.09 ERA this season. His team won their last 3 straight games this season with him making an appearance. In his last MLB start, he allowed 3 earned runs, 1 homer, and 3 BB with 6 strikeouts on 4 hits through 6 innings played against the Boston Red Sox.

The current betting odds have the Blue Jays listed as an underdog in this game according to Draftkings Sportsbook. The Blue Jays are currently leading this series 2-0 after winning both home games to start the series. Their pitching hasn't been great, but their offense has been and they have one of the best offenses in the MLB that also had a week off to rest. Meanwhile, the Yankees also have a great offense, but they haven't been hitting like the Blue Jays have been in these playoffs. The Yankees don't have a great bullpen either and they have been giving up quite a few runs in their games. Rodon is on the mound for the Yankees in this one and he has looked great all season. He is 18-9 with a 3.09 ERA, but lately he has been giving up more runs. The team has been having success with him lately as they have won 3 games in a row with him starting, but he did give up 3 earned runs against the Red Sox in the Wild Card Series. He had the offense on his side in that one, but those 3 earned runs could have been disastrous with the way their bullpen has pitched. Bieber is on the mound for the Blue Jays in this one and he has also looked good this season. He is 4-2 with a 3.57 ERA and he is making his first playoff start this year. He has looked really good to end the season, only giving up 2 earned runs in his last start which has been a common theme for him lately, and the team has won 4 of their last 5 games with him starting too. The Blue Jays have been rolling to start this series and they have all of the momentum with that red hot offense. The best way to place a bet here is on the Blue Jays to win this game. 

Blue Jays Yankees Prediction:  Our MLB Pick for Tuesday, October 7, 2025 (8:08 pm ET start time) is Blue Jays 4 Yankees 2.

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Toronto Blue Jays: 80-87 (+7.6 units) on the moneyline as an underdog of +100 to +150. 144-131 (+8.1 units) on the moneyline when playing against a team with a winning record. 59-51 (+9 units) on the moneyline vs. AL teams scoring 4.9 or more runs/game on the season. 22-13 OVER after scoring 10 runs or more.

New York Yankees: 279-225 (-20.7 units) on the moneyline in all games. 142-111 (-23.2 units) on the moneyline in home games. 215-159 (-30.1 units) on the moneyline as a favorite of -110 or higher. 31-22 OVER off a loss to a division rival as a favorite.

Toronto Blue Jays:  J. Berrios (SP) Fifteen Day IL - Elbow. T. France (1B) Ten Day IL - Oblique. C. Bassitt (SP) Fifteen Day IL - Back. B. Bichette (SS) Ten Day IL - Knee. R. Pina (SP) Sixty Day IL - Elbow. N. Sandlin (RP) Sixty Day IL - Elbow. Y. Garcia (RP) Sixty Day IL - Ankle. B. Francis (SP) Sixty Day IL - Shoulder. R. Burr (RP) Sixty Day IL - Shoulder. A. Bastardo (SP) Sixty Day IL - Elbow.

New York Yankees:  B. Headrick (RP) Fifteen Day IL - Forearm. J. Loaisiga (RP) Fifteen Day IL - Back. C. Schmidt (SP) Sixty Day IL - Forearm. O. Cabrera (3B) Sixty Day IL - Ankle. J. Cousins (RP) Sixty Day IL - Elbow. G. Cole (SP) Sixty Day IL - Elbow.

“It's happened a lot, but that was the best. I was kind of joking with [Kevin] Gausman, Max [Scherzer], Biebs [Shane Bieber] and [pitching coach] Pete Walker like, ‘Wish me luck, I'm going out there.’ That was special for him to kind of have that moment.” - John Schneider after his team’s win against the Yankees in game 2 on Sunday.

“Obviously it feels like the world's caving in around you -- you lose two games like that in their building, where it doesn't go right. But, all of a sudden, you go out there and win a ballgame on Tuesday, the needle can change.” - Aaron Boone after his team’s loss against the Blue Jays in game 2 on Sunday.

Trent Grisham (L) CF

Aaron Judge (R) RF

Cody Bellinger (L) LF

Ben Rice (L) 1B

Giancarlo Stanton (R) DH

Jazz Chisholm Jr. (L) 2B

Ryan McMahon (L) 3B

Anthony Volpe (R) SS

Austin Wells (L) C

George Springer (R) DH

Davis Schneider (R) LF

Vladimir Guerrero Jr. (R) 1B

Alejandro Kirk (R) C

Daulton Varsho (L) CF

Ernie Clement (R) 3B

Isiah Kiner-Falefa (R) 2B

Andrés Giménez (L) SS

Myles Straw (R) RF

Batting Average:  Joey Loperfido (.333)

Hits:  Bo Bichette (181)

Home Runs:  George Springer (32)

RBI:  Bo Bichette (94)

Stolen Bases:  George Springer (18)

Wins:  Chris Bassitt (11)

Saves:  Jeff Hoffman (33)

ERA:  Ryan Burr (0.00)

Batting Average:  Aaron Judge (.331)

Hits:  Aaron Judge (179)

Home Runs:  Aaron Judge (53)

RBI:  Aaron Judge (114)

Stolen Bases:  Jazz Chisholm (31)

Wins:  Max Fried (19)

Saves:  Devin Williams (18)

ERA:  Adam Ottavino (0.00)

Managers:

Toronto Blue Jays: John Schneider (4th season)

New York Yankees: Aaron Boone (8th season)