by Rod Pearson
Friday, Oct 24, 2025
Game Time: 4:05 pm ET, Sunday, October 26, 2025
Venue: Caesars Superdome, New Orleans, LA
Where to Watch: FOX
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Buccaneers -4.5, Saints +4.5; Over/Under: 46.5 points
Bet365: Point Spread: Buccaneers -4, Saints +4; Over/Under: 47 points
BetMGM: Point Spread: Buccaneers -4, Saints +4; Over/Under: 47 points
Season Record
Tampa Bay Buccaneers: 5-2 (1st place, NFC South)
New Orleans Saints: 1-6 (4th place, NFC South)
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Recent Form
Tampa Bay Buccaneers: lost their last game on the road against the Detroit Lions 24-9.
New Orleans Saints: lost their last game on the road against the Chicago Bears 26-14.
Tampa Bay Buccaneers vs New Orleans Saints Preview and Analysis
The Buccaneers are entering this game with a 5-2 record overall and they have a 1-0 record in their divisional games too. They are 2-1 in their home games, 3-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against the Detroit Lions 24-9. Baker Mayfield was the starting QB and he completed 28/50 passes for 228 passing yards, 1 touchdown, and 1 interception. Rachaad White led the team in rushing yards with 38. Cade Otton led the receivers with 65 receiving yards on 7 receptions. Tykee Smith led the defense in that game with 8 solo tackles and 5 assisted tackles while Tykee Smith, SirVocea Dennis, Anthony Nelson, and YaYa Diaby each led the defense in sacks with 1. Jamel Dean came away with the only interception for them in that one.
The Saints are entering this game with a 1-6 record overall and they have a 0-0 record in their divisional games too. They are 1-3 in their home games, 0-3 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against the Chicago Bears 26-14. Spencer Rattler was the starting QB and he completed 20/32 passes for 233 passing yards, 2 touchdowns, and 3 interceptions. Alvin Kamara led the team in rushing yards with 28. Chris Olave led the receivers with 98 receiving yards on 5 receptions and 2 TDs. Demario Davis led the defense in that game with 6 solo tackles and 4 assisted tackles while Chase Young and Bryan Bresee each led the defense in sacks with 0.5. Quincy Riley came away with the only interception for them in that one.
Buccaneers vs Saints Prediction
The current betting odds have the Buccaneers listed as a 4.5 point favorite in this game according to Draftkings Sportsbook. The Buccaneers have looked really good in their games this season with their 5-2 record overall which has them right at the top of the NFC South. They are off a bad 24-9 loss to the Lions in their last one, but they have looked like one of the best teams in the NFL all season and they will be looking to bounce back after that bad loss. They are still missing some key players, but their defense has looked great all season and their offense continues to find ways to score. Meanwhile, the Saints have looked terrible in their games this season with their 1-6 record overall which has them right at the bottom of the NFC South with one of the worst records in the entire NFL. They have looked better on their own field this season, but they still have a 1-3 home record this season and are one of the worst teams in the league. They are off a 26-14 loss to the Bears in their last one and their offense has struggled all season to put up points with Rattler not really being the answer at QB. The defense hasn't looked good against better offenses either, and the Buccaneers are one of the best teams in the NFL looking to bounce back after a bad loss. This is a bad situation for a struggling Saints team. The best way to place a bet here is on the Buccaneers to cover the spread in this game.
Buccaneers Saints Prediction: Our NFL Pick for Sunday, October 26, 2025 (4:05 pm ET start time) is Buccaneers 27 Saints 17.
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NFL Betting Trends
Tampa Bay Buccaneers: 16-6 ATS in road games. 8-4 ATS in a road game where the total is between 42.5 and 49 points. 12-4 ATS after 1 or more consecutive losses. 5-2 UNDER after scoring 14 points or less last game.
New Orleans Saints: 15-25 ATS in all games. 3-9 ATS as an underdog of 3.5 to 9.5 points. 6-12 ATS after playing their last game on the road. 12-6 UNDER after playing their last game on the road. 9-2 UNDER vs. bad defensive teams who give up 24 or more points/game.
Key Injuries
Tampa Bay Buccaneers: V. Vea (DL) Injured - Foot. H. Reddick (LB) Injured - Ankle. T. Bridgewater (QB) Injured - Teeth. L. David (LB) Injured - Knee. C. Godwin Jr. (WR) Injured - Fibula. B. Mayfield (QB) Injured - Knee. B. Bredeson (OG) Injured - Shoulder. A. Winfield Jr. (S) Injured - Toe. M. Jordan (OG) Injured - Knee. G. Gaines (DL) Injured - Toe. C. Izien (S) Injured - Knee. M. Watts (LB) Injured - Personal. L. Haggard (OT) Injured - Shoulder. Z. McCollum (CB) Injured - Thumb. B. Irving (RB) Injured - Foot. D. Culp (TE) Injured - Knee. J. Williams (RB) Injured - Concussion. E. Egbuka (WR) Injured - Hamstring.
New Orleans Saints: D. Godchaux (DL) Injured - NIR - Rest. C. Olave (WR) Injured - Ankle. A. Taylor (CB) Injured - Personal. C. Young (DL) Injured - Illness. J. Johnson (TE) Injured - Neck. A. Kamara (RB) Injured - Ankle.
Notable Quotes
“He’s a very talented running back and when you miss a gap, he can turn it into a big play.” - Todd Bowles after his team’s loss against the Lions in their last game.
“We can’t stop. We got to find some energy, find some inspiration. Everybody got to just dig deep and find that want-to.” - Alvin Kamara after their loss against the Bears in their last game.
Starting Lineups
Tampa Bay Buccaneers
WR Egbuka, Emeka
WR Johnson, Kameron
WR Johnson, Tez
TE Otton, Cade
QB Mayfield, Baker
RB White, Rachaad
New Orleans Saints
WR Olave, Chris
WR Cooks, Brandin
WR Shaheed, Rashid
TE Johnson, Juwan
QB Rattler, Spencer
RB Kamara, Alvin
Statistical Leaders
Tampa Bay Buccaneers
Passing: Baker Mayfield (1,767)
Rushing: Rachaad White (252)
Receiving: Emeka Egbuka (527)
Touchdowns: Emeka Egbuka (5)
New Orleans Saints
Passing: Spencer Rattler (1,450)
Rushing: Alvin Kamara (342)
Receiving: Chris Olave (440)
Touchdowns: Chris Olave (3)
Coaches:
Tampa Bay Buccaneers: Todd Bowles (4th season)
New Orleans Saints: Kellen Moore (1st season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
