Stanford Cardinal vs Notre Dame Fighting Irish Prediction, Picks and Game Preview - 10/10/2026

Game Time: 3:30 pm ET, Saturday, October 10, 2026

Venue:  Notre Dame Stadium, Notre Dame, IN

Where to Watch:  NBC

DraftKings:  Point Spread:  Stanford +38.5, Notre Dame -38.5; Over/Under:  54.5 points

Bet365:  Point Spread:  Stanford +38.5, Notre Dame -38.5; Over/Under:  54.5 points

BetMGM:  Point Spread:  Stanford +38.5, Notre Dame -38.5; Over/Under:  54.5 points

Stanford Cardinal:  2-3 (1-3) (13th place, ACC)

Notre Dame Fighting Irish:  5-0 (0-0) (FBS Independent)

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Stanford Cardinal:  lost their last game on the road against the Wake Forest Demon Deacons 57-3.

Notre Dame Fighting Irish:  won their last game on the road against the North Carolina Tar Heels 37-26.

Stanford is entering this game with a 2-3 record overall and they have a 1-3 record in their conference games too. They are 2-1 in their home games, 0-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against Wake Forest 57-3. Davis Warren was the starting QB and he completed 19/30 passes for 136 passing yards, 0 touchdowns, and 1 interception. Micah Ford led the team in rushing yards with 45. Nico Brown led the receivers with 42 receiving yards on 4 receptions. Jay Green led the defense in that game with 11 tackles while Gabe Kaminski and Omar Staples each led the defense in sacks with 0.5. No one on the defense came away with an interception for them in that one.

 

 

 

Notre Dame is entering this game with a 5-0 record overall and they have a 0-0 record in their conference games too. They are 2-0 in their home games, 2-0 in their road games, and they are also 1-0 in their neutral site games this season, but they will be at home for this game. They won their last game against North Carolina 37-26. CJ Carr was the starting QB and he completed 21/29 passes for 234 passing yards, 4 touchdowns, and 0 interceptions. Jonaz Walton led the team in rushing yards with 120. Jordan Faison led the receivers with 132 receiving yards on 8 receptions and 2 TDs. Boubacar Traore led the defense in that game with 6 tackles while Francis Brewu led the defense in sacks with 1. Kyngstonn Viliamu-Asa and Luke Talich each came away with 1 interception for them in that one.

The current betting odds have Notre Dame listed as a 38.5 point favorite in this game according to Draftkings Sportsbook. Notre Dame has looked great in their games this season with their 5-0 record overall which has them ranked inside the top 25. They have looked good on their home field too with their 2-0 home record this season. Meanwhile, Stanford has looked terrible in their games this season with their 2-3 record overall and their 1-3 conference record which has them right near the bottom of the ACC. They have been a bad road team too with their 0-2 road record this year. Stanford hired a new head coach this year and has been looking to turn this program around, but it looks like nothing is going to change for them this season. They have already played 4 conference games in 5 weeks and it feels like their season is over with the way they have performed. They are coming off a 57-3 loss to Wake Forest in their last one and their losses this season haven't really been that competitive. They haven't had the easiest schedule either, but now they are going on the road against another ranked opponent who has the potential to be one of the best in the nation. Notre Dame is coming off a 37-26 win over North Carolina in their last one and they didn't play their best game, but they have also been rolling over a lot of their opponents this year. The defense will be looking to bounce back with a better game against this Stanford offense that hasn't been able to do much all year and Stanford's defense is going to have no answers for CJ Carr and company. Look for Notre Dame to play a better game at home against a bad opponent and continue rolling like one of the best teams in the nation. The best way to place a bet here is on Notre Dame to cover the spread in this game. 

Stanford Notre Dame Prediction:  Our NCAAF Pick for Saturday, October 10, 2026 (3:30 pm ET start time) is Notre Dame 56 Stanford 7.

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Stanford Cardinal: 28-42 ATS after scoring 14 points or less last game. 26-34 ATS against teams with a turnover margin of +1 per game or better. 28-39 ATS off a road loss against a conference rival. 39-27 UNDER in a road game where the total is between 49.5 and 56.

Notre Dame Fighting Irish: 32-18 ATS vs. poor passing defenses - allowing 8 or more passing yards/att. 30-21 ATS when playing against a bad team (Win Pct. 25% to 40%). 29-18 ATS vs. bad defensive teams who give up 31 or more points/game. 12-5 UNDER vs. poor teams - outscored by 10+ points per game on the season.

Stanford Cardinal:  N. Prongos (OG) Questionable - Undisclosed. L. Bironas (K) Questionable - Undisclosed. D. Sharper (WR) Questionable - Undisclosed. C. Shaw (WR) Questionable - Undisclosed. A. Kilstrom (OG) Questionable - Undisclosed. J. Galvan (LB) Out - Undisclosed.

Notre Dame Fighting Irish:  L. Moore (CB) Questionable - Concussion. K. Viliamu-Asa (LB) Questionable - Thumb. B. Hebert (QB) Questionable - Undisclosed. Q. Porter (WR) Out - Knee.

“It’s on me to figure out how we can play better, period, and then how we can play better on the road.” - Tavita Pritchard after his team’s loss against Wake Forest in their last game.  

“When they know you’re going to try to run the ball — and you’re still able to run the ball — because of the weather conditions, that’s a reflection of your team, and the toughness and the physicality.” - Marcus Freeman after his team’s win against UNC in their last game. 

WR Onovughe, Jordan

WR Hall, JonAnthony

WR Thorpe, Liam

TE Blackburn, Benji

QB Warren, Davis

RB Ford, Micah

WR Faison, Jordan

WR Gilbert, Micah

WR Graham, Mylan

TE Flanagan, Cooper

QB Carr, CJ 

RB Williams, Aneyas

Passing: Davis Warren (1,207)

Rushing: Micah Ford (302)

Receiving: Caden High (266)

Touchdowns: Micah Ford (4)

Passing: CJ Carr (1,197)

Rushing: Aneyas Williams (266)

Receiving: Jordan Faison (371)

Touchdowns: Nolan James Jr. (6)

Coaches:

Stanford Cardinal: Tavita Pritchard (1st season)

Notre Dame Fighting Irish: Marcus Freeman (6th season)