by Rod Pearson
Tuesday, Sep 01, 2026
Game Time: 10:10 pm ET, Wednesday, September 2, 2026
Venue: Dodger Stadium, Los Angeles, CA
Where to Watch: MLB TV
Opening Odds at USA Sportsbooks
DraftKings: Moneyline odds: Cardinals +200, Dodgers -250; Over/Under: 7.5 runs
Bet365: Moneyline odds: Cardinals +200, Dodgers -250; Over/Under: 7.5 runs
BetMGM: Moneyline odds: Cardinals +200, Dodgers -250; Over/Under: 7.5 runs
Season Record
St Louis Cardinals: 68-70 (3rd place, NL Central)
Los Angeles Dodgers: 82-55 (1st place, NL West)
Do not miss out on our expert handicapper analysis! Kyle Hunter is on a HOT STREAK in MLB on a 17-8-1 MLB RUN for +$8,240 PROFIT! Make sure you check out his picks and many more from the expert handicappers featured in the Shop Picks section.
Recent Form
St Louis Cardinals: 3-7 last 10
Los Angeles Dodgers: 6-4 last 10
St Louis Cardinals vs Los Angeles Dodgers Preview and Analysis
The Cardinals are entering this series off a loss and lost their 3-game series against the Pittsburgh Pirates 2-1 in their last series. They enter this game with a 68-70 record overall and have a road record of 34-32. This is the 2nd game of a 3-game series with the Dodgers on Wednesday with the series opener still to be played on Monday. Their offense ranks 25th in the MLB with a .696 OPS. Michael McGreevy is their starting pitcher on Tuesday while Andre Pallante is making his start in this game on Wednesday. He is 12-6 with a 3.57 ERA this season. His team won 2 of their last 3 games this season with him making an appearance. In his last MLB regular season appearance, he allowed 4 ER, 0 HR, and 1 BB with 5 SO on 10 hits through 6 IP against the Cincinnati Reds.
The Dodgers are entering this series off a win and won their 3-game series against the Detroit Tigers 2-1 in their last series. They enter this game with an 82-55 record overall and have a home record of 40-26. This is the 2nd game of a 3-game series with the Cardinals on Wednesday with the 1st game of this series still to be played on Tuesday. Their offense ranks 2nd in the MLB with a .757 OPS. Eric Lauer is their starting pitcher on Tuesday while Yoshinobu Yamamoto is making his start in this game on Wednesday. He is 12-8 with a 2.56 ERA this season. His team won 3 of their last 4 games this season with him making an appearance. In his last MLB regular season start, he allowed 1 earned run, 1 homer, and 1 walk with 8 strikeouts on 4 hits through 6.1 innings pitched against the Atlanta Braves.
Cardinals vs Dodgers Prediction
The current betting odds have the Dodgers listed as a big favorite in this game according to Draftkings Sportsbook. The Dodgers have looked great in their games this season with their 82-55 record overall which has them right at the top of the NL West. They have looked great in their own ballpark too with their 40-26 home record this season. Meanwhile, the Cardinals haven't looked great in their games this season with their 68-70 record overall which has them right in the middle of the NL West. They have been a good road team though with their 34-32 road record this year. The Dodgers haven't been at their best over the last month, but lately they have been getting hot again, now 6-4 in their last 10 games. The Cardinals have looked terrible though, going 3-7 in their last 10 games which has put them further out of the Wild Card race now, and they have been giving up a ton of runs too. They have been dealing with some injuries to their starting rotation and with their playoff hopes starting to dwindle now, they aren't going to have the best option on the mound in this one. The Dodgers are going with Yamamoto though and he has looked great this season. He is 12-8 with a 2.56 ERA and he has been their ace this season. He is coming off another great start giving up 1 earned run which has been a common theme for him all year and the team has been having a lot of success with him too, winning 3 of their last 4 games with him starting. The Dodgers are also still chasing the Brewers for the best record in MLB, so look for them to take advantage of this pitching matchup and continue surging. The best way to place a bet here is on the Dodgers to win this game and on the runline.
Cardinals Dodgers Prediction: Our MLB Pick for Wednesday, September 2, 2026 (10:10 pm ET start time) is Dodgers 8 Cardinals 3.
Don't miss our champion handicappers free picks, best bets, and expert baseball picks today. And if you enjoyed this St Louis Cardinals Los Angeles Dodgers prediction, be sure to drop by every day for our daily MLB projections and previews.
MLB Betting Trends
St Louis Cardinals: 60-57 (+17.4 units) on the moneyline when playing against a good team (Win Pct. 54% to 62%). 73-72 (+17.9 units) on the moneyline vs. teams outscoring opp by 0.5 or more runs/game on the season. 65-65 (+9.7 units) on the moneyline vs. an NL starting pitcher whose WHIP is 1.250 or better. 13-6 UNDER against NL West opponents.
Los Angeles Dodgers: 47-45 (-21.7 units) on the moneyline against NL Central opponents. 297-197 (-23.2 units) on the moneyline in all games. 156-89 (-16.6 units) on the moneyline in home games. 35-22 UNDER vs. an NL team with a slugging percentage .400 or worse on the season.
Key Injuries
St Louis Cardinals: J. Wetherholt (2B) Ten Day IL - Wrist. B. Jordan (3B) Ten Day IL - Ankle. P. Strzelecki (RP) Fifteen Day IL - Forearm. M. Winn (SS) Ten Day IL - Thumb. E. Pereira (RF) Ten Day IL - Hand. H. Dobbins (SP) Fifteen Day IL - Forearm. A. Pallante (SP) Fifteen Day IL - Elbow. M. Rajcic (SP) Sixty Day IL - Elbow.
Los Angeles Dodgers: R. Sasaki (SP) Fifteen Day IL - Finger. A. Pages (CF) Ten Day IL - Hand. E. Diaz (RP) Fifteen Day IL - Neck. J. Wrobleski (SP) Fifteen Day IL - Forearm. B. Treinen (RP) Sixty Day IL - Elbow. D. Rushing (C) Ten Day IL - Arm. W. Klein (RP) Fifteen Day IL - Elbow. W. Smith (C) Sixty Day IL - Neck. K. Bubic (SP) Sixty Day IL - Elbow. B. Graterol (RP) Sixty Day IL - Shoulder. B. Casparius (RP) Sixty Day IL - Shoulder. J. Cousins (RP) Sixty Day IL - Elbow. G. Stone (SP) Sixty Day IL - Shoulder. B. Miller (SP) Sixty Day IL - Shoulder.
Notable Quotes
“We agreed to, if it wasn’t going to continue to improve, then we would hit the pause button. We got to the point yesterday where it just didn’t feel good. So, we’ll give it the appropriate rest and then move forward from there.” - Oliver Marmol on the injury to JJ Wetherholt.
"It was good to see Teo break out today. I know he’s been wanting it. Just the at-bats, the walks, controlling the strike zone, throwing out some hits, building some innings -- it was really good to see." - Dave Roberts after his team’s win against the Tigers in their game on Sunday.
Starting Lineups
St Louis Cardinals
Bryan Torres (L) LF
Iván Herrera (R) C
Alec Burleson (L) 1B
Jordan Walker (R) RF
Nolan Gorman (L) DH
José Fermín (R) 2B
Nathan Church (L) CF
Ramón Urías (R) 3B
Thomas Saggese (R) SS
Los Angeles Dodgers
Shohei Ohtani (L) DH
Tommy Edman (S) 2B
Mookie Betts (R) SS
Freddie Freeman (L) 1B
Teoscar Hernández (R) LF
Miguel Rojas (R) 3B
Kyle Tucker (L) RF
Enrique Hernández (R) CF
Ben Rortvedt (L) C
Statistical Leaders
St Louis Cardinals
Batting Average: Alec Burleson (.288)
Hits: Alec Burleson (150)
Home Runs: Jordan Walker (27)
RBI: Alec Burleson (100)
Stolen Bases: Jordan Walker (18)
Wins: Andre Pallante (12)
Saves: Riley O'Brien (34)
ERA: Cade Winquest (0.00)
Los Angeles Dodgers
Batting Average: Freddie Freeman (.304)
Hits: Freddie Freeman (153)
Home Runs: Shohei Ohtani (30)
RBI: Andy Pages (80)
Stolen Bases: Andy Pages (12)
Wins: Yoshinobu Yamamoto (12)
Saves: Tanner Scott (20)
ERA: Seth Halvorsen (0.00)
Managers:
St Louis Cardinals: Oliver Marmol (5th season)
Los Angeles Dodgers: Dave Roberts (11th season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
