South Florida Bulls vs Miami Hurricanes Prediction, Picks and Game Preview - 09/13/2025

Game Time: 4:30 pm ET, Saturday, September 13, 2025

Venue:  Hard Rock Stadium, Miami Gardens, FL

Where to Watch:  The CW Network

DraftKings:  Point Spread:  USF +17.5, Miami-FL -17.5; Over/Under:  56.5 points

Bet365:  Point Spread:  USF +17.5, Miami-FL -17.5; Over/Under:  56.5 points

BetMGM:  Point Spread:  USF +17.5, Miami-FL -17.5; Over/Under:  56.5 points

South Florida Bulls:  2-0 (0-0) (6th place, American)

Miami Hurricanes:  2-0 (0-0) (5th place, ACC)

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South Florida Bulls:  won their last game on the road against the Florida Gators 18-16.

Miami Hurricanes:  won their last game at home against the Bethune-Cookman Wildcats 45-3.

South Florida is entering this game with a 2-0 record overall and they have a 0-0 record in their conference games too. They are 1-0 in their home games, 1-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against Florida 18-16. Byrum Brown was the starting QB and he completed 23/36 passes for 263 passing yards, 1 touchdown, and 0 interceptions. Byrum Brown led the team in rushing yards with 66. Keshaun Singleton led the receivers with 75 receiving yards on 2 receptions and 1 TD. Jarvis Lee led the defense in that game with 5 solo tackles and 1 assisted tackle while Mac Harris led the defense in sacks with 1. James Chenault came away with the only interception for them in that one.

 

 

 

Miami-Florida is entering this game with a 2-0 record overall and they have a 0-0 record in their conference games too. They are 2-0 in their home games, 0-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against Bethune-Cookman 45-3. Carson Beck was the starting QB and he completed 22/24 passes for 267 passing yards, 2 touchdowns, and 0 interceptions. Mark Fletcher Jr. led the team in rushing yards with 86 and 2 TDs. Malachi Toney led the receivers with 80 receiving yards on 6 receptions. Kellen Wiley Jr. led the defense in that game with 3 solo tackles and 2 assisted tackles while Rueben Bain Jr. led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.

The current betting odds have South Florida listed as a 17.5 point favorite in this game according to Draftkings Sportsbook. South Florida has a 2-0 record overall this season and they have looked great to start the season. They are now a ranked team and they are also the only team in the nation with 2 ranked wins under their belt, beating Boise State in week 1 and now coming off a huge upset win on the road over Florida last week. They are making a statement to be a threat for that group of 5 playoff spot this year and so far they have shown that they can win in different ways, beating Boise State with offense in week 1 and beating Florida with defense last week. Meanwhile, Miami has a 2-0 record overall this season and they have looked great in their 2 games. They just beat up on a team from the FCS in their last one, but they opened the season with a big home win over Notre Dame. As good as they looked in that Notre Dame win, they struggled to put Notre Dame away and that allowed them back into the game with a chance to win it in the end. Miami has a lot more talent on both sides of the ball than this South Florida team, but those late game decisions are something that has plagued this Miami team in recent years and this is not the kind of team that they want hanging around late in this game. This is still an in-state rivalry too so South Florida is going to bring their best effort in this one and they are the team this year that has a lot more to prove. The best way to place a bet here is on South Florida to cover the spread in this game. 

South Florida Miami Prediction:  Our NCAAF Pick for Saturday, September 13, 2025 (4:30 pm ET start time) is Miami 24 South Florida 17.

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South Florida Bulls: 6-3 ATS as a road underdog. 9-4 ATS in non-conference games. 4-1 ATS off an upset win as an underdog. 4-1 OVER off an upset win as an underdog. 7-4 OVER after playing their last game on the road.

Miami Hurricanes: 1-4 ATS when the total is between 56.5 and 63. 1-5 ATS after a game with a turnover margin of +2 or better. 3-8 1H ATS as a home favorite. 18-9 OVER in all lined games. 4-1 OVER when the total is between 56.5 and 63.

South Florida Bulls:  J. Chenault (CB) Questionable - Undisclosed. D. Butler (DL) Questionable - Undisclosed.

Miami Hurricanes:  J. Lyle (RB) Questionable - Undisclosed. J. Trader (WR) Questionable - Undisclosed.

“A bunch of guys that bought into a vision when it wasn't super cool.” - Alex Golesh after his team’s win against Florida in their last game. 

“He keeps getting better and better. I mean, every practice, every week, there’s this continued growth and development, and really you see an appetite for more. He just wants to get better. He wants Miami to get to better. He wants to Miami to win. And he’s all about team.” - Mario Cristobal after his team’s win against BCU in their last game. 

WR Singleton, Keshaun

WR Reuben, Mudia

WR Smith, JeyQuan

TE Wolff, Weston

QB Brown, Byrum

RB Norton, Cartevious

WR Daniels, CJ

WR Marion, Keelan

WR Toney, Malachi 

TE Bauman, Alex

TE Lofton, Elija

QB Beck, Carson

RB Fletcher Jr., Mark

Passing: B. Brown (473)

Rushing: B. Brown (109)

Receiving: K. Singleton (168)

Touchdowns: B. Brown (2)

Passing: C. Beck (472)

Rushing: M. Fletcher Jr. (152)

Receiving: M. Toney (162)

Touchdowns: C. Daniels (3)

Coaches:

South Florida Bulls: Alex Golesh (3rd season)

Miami Hurricanes: Mario Cristobal (4th season)