South Alabama Jaguars vs Auburn Tigers Prediction, Picks and Game Preview - 09/13/2025

Game Time: 12:45 pm ET, Saturday, September 13, 2025

Venue:  Jordan-Hare Stadium, Auburn University, AL 

Where to Watch:  SEC Network

DraftKings:  Point Spread:  South Alabama +25.5, Auburn -25.5; Over/Under:  53.5 points

Bet365:  Point Spread:  South Alabama +24.5, Auburn -24.5; Over/Under:  53.5 points

BetMGM:  Point Spread:  South Alabama +25.5, Auburn -25.5; Over/Under:  53.5 points

South Alabama Jaguars:  1-1 (0-0) (2nd place, Sun Belt West)

Auburn Tigers:  2-0 (0-0) (7th place, SEC)

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South Alabama Jaguars:  lost their last game at home against the Tulane Green Wave 33-31. 

Auburn Tigers:  won their last game at home against the Ball State Cardinals 42-3.

South Alabama is entering this game with a 1-1 record overall and they have a 0-0 record in their conference games too. They are 1-1 in their home games, 0-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against Tulane 33-31. Bishop Davenport was the starting QB and he completed 17/24 passes for 231 passing yards, 2 touchdowns, and 0 interceptions. Kentrel Bullock led the team in rushing yards with 107 and 1 TD. Devin Voisin led the receivers with 152 receiving yards on 8 receptions and 2 TDs. Wesley Miller led the defense in that game with 6 solo tackles and 3 assisted tackles while Dominic Wiseman led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.

 

 

 

Auburn is entering this game with a 2-0 record overall and they have a 0-0 record in their conference games too. They are 1-0 in their home games, 1-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against Ball State 42-3. Jackson Arnold was the starting QB and he completed 24/28 passes for 251 passing yards, 3 touchdowns, and 0 interceptions. Jeremiah Cobb led the team in rushing yards with 121 and 2 TDs. Cam Coleman led the receivers with 77 receiving yards on 7 receptions. Sylvester Smith led the defense in that game with 6 solo tackles and 0 assisted tackles while Xavier Atkins and Keyron Crawford each led the defense in sacks with 2. No one on the defense came away with an interception for them in that one.

The current betting odds have Auburn listed as a 25.5 point favorite in this game according to Draftkings Sportsbook. Auburn has looked great in their games this season with their 2-0 record overall. They just beat Ball State at home 42-3 in their last game, but they did already get tested on the road in their first game of the season. They beat Baylor on the road in week 1, beating them 38-24, and they ran away with that game as it was never really close once they took a lead. The run game has been great and the offense has looked great with Jackson Arnold too. Meanwhile, South Alabama hasn't looked great in their games this season with their 1-1 record overall. They beat a team from the FCS in week 1 and they just lost their last game at home to a good Tulane team. They lost to Tulane 33-31 and made it really close in the end, but they also jumped out to a 14-0 lead and that lead evaporated in no time. That defense is a big issue and it is going to be an even bigger issue here against an SEC opponent in their first road game of the year. South Alabama isn't going to be able to move the ball as easily against this Auburn defense that has a lot more talent, and that South Alabama defense is definitely not going to stop this Auburn offense on the road. South Alabama could put up some points here, but their offense won't look as good in this first road game and they won't be able to keep up with that Auburn offense either. The best way to place a bet here is on Auburn to cover the spread in this game. 

South Alabama Auburn Prediction:  Our NCAAF Pick for Saturday, September 13, 2025 (12:45 pm ET start time) is Auburn 56 South Alabama 21.

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South Alabama Jaguars: 16-7 ATS on the road in the first month of the season. 13-7 1H OVER after a loss by 6 or less points. 8-4 UNDER in road lined games. 4-1 UNDER off a home loss. 8-4 UNDER after 1 or more consecutive straight up losses.

Auburn Tigers: 2-7 ATS when the total is between 49.5 and 56. 1-4 ATS off a home win by 17 points or more. 1-7 ATS after scoring 37 points or more last game. 8-1 UNDER when the total is between 49.5 and 56. 7-1 UNDER after allowing 14 points or less last game.

South Alabama Jaguars:  None.

Auburn Tigers:  D. Alston (RB) Questionable - Shoulder.

“They’re just day-to-day right now. It’s just still kind of fresh, still trying to get (medical test) results and those type of things. I’m optimistic, but I don’t have a definitive (answer) right now to be able to tell you.” - Major Applewhite on his team’s injuries coming into this week.

“It’s good to give our fans that kind of a game here at home. We’ve got seven opportunities here. They have to matter.” - Hugh Freeze after his team’s win against Ball State in their last game. 

WR Voisin, Devin

WR Jenkins, Brendan

WR Eager, Anthony

TE Thomas, Trent

QB Davenport, Bishop

RB Bullock, Kentrel

WR Coleman, Cam

WR Fields, Horatio

WR Singleton Jr., Eric

TE Frazier, Brandon

QB Arnold, Jackson

RB Alston, Damari

Passing: B. Davenport (397)

Rushing: K. Bullock (234)

Receiving: D. Voisin (221)

Touchdowns: D. Voisin (3)

Passing: J. Arnold (359)

Rushing: J. Cobb (195)

Receiving: C. Coleman (100)

Touchdowns: J. Cobb (3)

Coaches:

South Alabama Jaguars: Major Applewhite (2nd season)

Auburn Tigers: Hugh Freeze (3rd season)