Seattle Seahawks vs Carolina Panthers Prediction, Preview and Odds - 12/28/2025

Game Time: 1:00 pm ET, Sunday, December 28, 2025

Venue:  Bank of America Stadium, Charlotte, NC 

Where to Watch:  CBS

DraftKings:  Point Spread:  Seahawks -7, Panthers +7; Over/Under:  42.5 points

Bet365:  Point Spread:  Seahawks -7, Panthers +7; Over/Under:  42.5 points

BetMGM:  Point Spread:  Seahawks -7, Panthers +7; Over/Under:  42.5 points

Seattle Seahawks:  12-3 (1st place, NFC West)

Carolina Panthers:  8-7 (1st place, NFC South)

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Seattle Seahawks:  won their last game at home against the Los Angeles Rams 38-37 in overtime. 

Carolina Panthers:  won their last game at home against the Tampa Bay Buccaneers 23-20.

The Seahawks are entering this game with a 12-3 record overall and they have a 3-2 record in their divisional games too. They are 6-2 in their home games, 6-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against the Los Angeles Rams 38-37 in OT. Sam Darnold was the starting QB and he completed 22/34 passes for 270 passing yards, 2 touchdowns, and 2 interceptions. Kenneth Walker III led the team in rushing yards with 100 and 1 TD. Jaxon Smith-Njigba led the receivers with 96 receiving yards on 8 receptions and 1 TD. Nick Emmanwori led the defense in that game with 7 solo tackles and 4 assisted tackles while no one on the defense recorded a sack for them. No one on the defense came away with an interception for them in that one.

 

 

 

The Panthers are entering this game with an 8-7 record overall and they have a 3-2 record in their divisional games too. They are 5-2 in their home games, 3-5 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the Tampa Bay Buccaneers 23-20. Bryce Young was the starting QB and he completed 21/32 passes for 191 passing yards, 2 touchdowns, and 0 interceptions. Rico Dowdle led the team in rushing yards with 29. Tetairoa McMillan led the receivers with 73 receiving yards on 6 receptions and 1 TD. Nick Scott led the defense in that game with 9 solo tackles and 1 assisted tackle while Christian Rozeboom and Derrick Brown each led the defense in sacks with 1. Lathan Ransom came away with the only interception for them in that one.

The current betting odds have the Seahawks listed as a 7 point favorite in this game according to Draftkings Sportsbook. The Seahawks have looked great in their games this season with their 12-3 record overall which has them right at the top of the NFC West with one of the best records in the entire NFL. They have been a great road team this season too with their 6-1 road record. Meanwhile, the Panthers have looked good in their games this season with their 8-7 record overall which has them right at the top of the NFC South. They have looked a lot better on their home field too with their 5-2 home record this year. The Panthers have had a great season as they have a chance to win the division and make the playoffs for the first time in years. They are off a big win over the Buccaneers in their last one, winning 23-20, but this isn't a great situation for them. They would love to win this game at home since they would clinch the division with a Bucs loss, but this game definitely doesn't matter as much as their regular season finale. They can lose this game and they would still win the division with a win over the Buccaneers next week so this is a bad situation for them off that big win. The Seahawks have been rolling lately and they are going to have a ton of momentum as they are off a 38-37 win over the Rams in their last one. That game was also on Thursday so they have had some extra time to prepare for this game, and the Seahawks are going to bring their best effort since they can earn the number 1 seed in the NFC still. The best way to place a bet here is on the Seahawks to cover the spread in this game. 

Seahawks Panthers Prediction:  Our NFL Pick for Sunday, December 28, 2025 (1:00 pm ET start time) is Seahawks 24 Panthers 14.

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Seattle Seahawks: 4-1 ATS against NFC South division opponents. 15-7 ATS in road games. 9-3 ATS after scoring 30 points or more last game. 4-1 OVER against NFC South division opponents. 11-4 OVER as a favorite of 3.5 to 9.5 points.

Carolina Panthers: 6-11 ATS vs. good passing teams averaging 235 or more passing yards/game. 4-10 ATS when playing against a team with a winning record. 7-15 ATS in games played on turf. 4-1 OVER against NFC West division opponents. 17-9 OVER in all games where the total is between 42.5 and 49 points.

Seattle Seahawks:  None.

Carolina Panthers:  None.

“It was something we talked about throughout the season and particularly for this game because of the playoff situation. You know, you play for the tie and lock up a playoff seat, but I just felt great about our play and I trusted our guys.” - Mike Macdonald after his team’s win against the LA Rams in their last game. 

“Everything is right in front of us still. To give ourselves a chance to play meaningful football at this time of the year, those guys have earned that. They have earned because of the work they put in and being accountable to each other.” - Dave Canales after his team’s win against the Buccaneers in their last game. 

WR Smith-Njigba, Jaxon

WR Shaheed, Rashid

WR Kupp, Cooper

TE Barner, AJ 

QB Darnold, Sam

RB Walker III, Kenneth

FB Ouzts, Robbie

WR McMillan, Tetairoa

WR Legette, Xavier

WR Coker, Jalen

TE Tremble, Tommy

QB Young, Bryce

RB Dowdle, Rico 

Passing: Sam Darnold (3,703)

Rushing: Kenneth Walker III (879)

Receiving: Jaxon Smith-Njigba (1,637)

Touchdowns: Jaxon Smith-Njigba (10)

Passing: Bryce Young (2,691)

Rushing: Rico Dowdle (1,007)

Receiving: Tetairoa McMillan (924)

Touchdowns: Rico Dowdle (7)

Coaches:

Seattle Seahawks: Mike Macdonald (2nd season)

Carolina Panthers: Dave Canales (2nd season)