San Antonio Spurs vs Portland Trail Blazers Prediction, Preview and Odds - 04/26/2026

Game Time: 3:30 pm ET, Sunday, April 26, 2026

Venue:  Moda Center, Portland, OR 

Where to Watch:  ESPN

DraftKings:  Point Spread:  Spurs -5.5, Trail Blazers +5.5; Over/Under:  218.5 points

Bet365:  Point Spread:  Spurs -5.5, Trail Blazers +5.5; Over/Under:  218.5 points

BetMGM:  Point Spread:  Spurs -5.5, Trail Blazers +5.5; Over/Under:  218.5 points

San Antonio Spurs:  62-20 (1st place, Southwest Division)

Portland Trail Blazers:  42-40 (4th place, Northwest Division)

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San Antonio Spurs:  7-3 last 10

Portland Trail Blazers:  6-4 last 10

The Spurs are entering the playoffs with a 62-20 record overall this season and they were 29-12 in their road games where they will be in this game. They are entering this game off a win against the Portland Trail Blazers. Stephon Castle led the team in points in that game with 33 while Dylan Harper was next on the team with 27 points. De'Aaron Fox led the team in assists in that game with 6 while Luke Kornet and Dylan Harper each led the team in rebounds with 10. They were 47.1% from the field, 48.5% from 3-point range, and 78.6% from the free throw line with their shots in that game. Their offense is averaging 119.8 PPG and their defense is allowing their opponents to average 111.5 PPG against them. The Spurs have an ATS record of 47-36-2 this season and their O/U record is 37-48.

The Trail Blazers are entering the playoffs with a 42-40 record overall this season and they were 24-17 in their home games where they will be in this game. They are entering this game off a loss against the San Antonio Spurs. Jrue Holiday led the team in points in that game with 29 while Scoot Henderson was next on the team with 21 points. Deni Avdija led the team in assists in that game with 9 while Donovan Clingan led the team in rebounds with 11. They were 41.1% from the field, 36.8% from 3-point range, and 69% from the free throw line with their shots in that game. Their offense is averaging 115.5 PPG and their defense is allowing their opponents to average 115.8 PPG against them. The Trail Blazers have an ATS record of 46-39 this season and their O/U record is 43-42.

The current betting odds have the Spurs listed as a 5.5 point favorite in this game according to Draftkings Sportsbook. The Spurs have looked great in their games this season with their 62-20 record overall which had them right near the top of the West with one of the best records in the entire NBA. They have been a great road team too with their 29-12 road record this year. Meanwhile, the Trail Blazers have looked good in their games this season with their 42-40 record overall which had them right in the middle of the West. They have also looked a lot better on their home court with their 24-17 home record this season. This is game 4 of a 7-game series between the 2 seeded Spurs and the 7 seeded Trail Blazers in the West for the 1st round of the NBA playoffs. The Spurs have a 2-1 series lead after winning game 3 by a score of 120-108. The Spurs lost Wemby to a concussion in game 2 of this series and they went on to lose that one, giving the home advantage to the Trail Blazers, but they got it back in game 3 with a double digit win on the road. The Spurs were still missing Wemby in that one, but they still have a lot of talent without him and were able to step up in his absence. Now the Spurs have control of this series once again and they are only going to get stronger as they could be getting Wemby back for this one. Even if he misses this game again, the Spurs have shown that they still have the talent to crush teams without him and they have all of the momentum back on their side in this series. The Trail Blazers are still a really young team that was ahead of schedule this season, but they have had a lot of trouble in this series against one of the best defensive teams in the NBA and they don't have the talent to hang with the Spurs in this series. Look for the Spurs to come out with their best effort to win this game and give themselves a chance to end this series at home in the next one. The best way to place a bet here is on the Spurs to cover the spread in this game. 

Spurs Trail Blazers Prediction:  Our NBA Pick for Sunday, April 26, 2026 (3:30 pm ET start time) is Spurs 111 Trail Blazers 102.

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San Antonio Spurs: 24-17 ATS in road games. 11-6 ATS when the total is 210 to 219.5. 30-20 ATS when playing against a team with a winning record. 29-22 UNDER off a road win.

Portland Trail Blazers: 7-16 ATS in a home game where the total is 210 to 219.5. 17-31 ATS versus good rebounding teams - outrebounding opponents by 3+ per game. 20-29 ATS when playing 4 or less games in 10 days. 28-20 UNDER as an underdog. 14-5 UNDER versus good rebounding teams - outrebounding opponents by 3+ per game.

San Antonio Spurs:  V. Wembanyama (C) Day To Day - Concussion Protocol. J. McLaughlin (PG) Day To Day - Ankle. D. Jones Garcia (SF) Out For Season - Ankle.

Portland Trail Blazers:  D. Lillard (PG) Out For Season - Achilles.

“I feel like we have a lot of confidence in ourselves. We know how good we are. So, down 10, down 15, in a game like that, with a lot of time to go, we just need to string some stops together and keep fighting. I feel we have a lot of dogs that aren't going to quit on our team.” - Stephon Castle after their win against the Trail Blazers in the 3rd game of this series on Friday

“This loss hurts, but we've got another one Sunday, so you can't really hang your hat on it too low. Maybe take it on the chin tonight, and then tomorrow, we've got to get back to work.” - Jrue Holiday after their loss against the Spurs in game 3 of this series on Friday.

PG De'Aaron Fox

SG Stephon Castle

SF Devin Vassell

PF Julian Champagnie

C Victor Wembanyama

PG Scoot Henderson

SG Jrue Holiday

SF Toumani Camara

PF Deni Avdija

C Donovan Clingan

PPG: Victor Wembanyama (25)

APG: Stephon Castle (7.4)

Reb/G: Victor Wembanyama (11.5)

PPG: Deni Avdija (24.2)

APG: Deni Avdija (6.7)

Reb/G: Donovan Clingan (11.6)

Coaches:

San Antonio Spurs: Mitch Johnson (2nd season)

Portland Trail Blazers: Tiago Splitter (1st season)