San Antonio Spurs vs New York Knicks Prediction, Preview and Odds - 12/16/2025

Game Time: 8:30 pm ET, Tuesday, December 16, 2025

Venue:  T-Mobile Arena, Las Vegas, NV

Where to Watch:  Prime Video

DraftKings:  Point Spread:  Spurs +2.5, Knicks -2.5; Over/Under:  228.5 points

Bet365:  Point Spread:  Spurs +2.5, Knicks -2.5; Over/Under:  228.5 points

BetMGM:  Point Spread:  Spurs +2.5, Knicks -2.5; Over/Under:  228.5 points

San Antonio Spurs:  18-7 (2nd place, Southwest Division)

New York Knicks:  18-7 (1st place, Atlantic Division)

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San Antonio Spurs:  7-3 last 10

New York Knicks:  9-1 last 10

The Spurs are entering this game with an 18-7 record overall this season and they are 8-5 in their road games this season, but they will be at a neutral site for this game. They are entering this game on a 3 game winning streak with wins coming against the New Orleans Pelicans, the Los Angeles Lakers, and the Oklahoma City Thunder. Devin Vassell led the team in points in that game with 23 while Stephon Castle, De'Aaron Fox, and Victor Wembanyama each were next on the team with 22 points. Harrison Barnes led the team in assists in that game with 5 while Victor Wembanyama led the team in rebounds with 9. They were 41.1% from the field, 31% from 3-point range, and 75% from the free throw line with their shots in that game. Their offense is averaging 119.7 PPG and their defense is allowing their opponents to average 115.2 PPG against them. The Spurs have an ATS record of 13-10-2 this season and their O/U record is 14-11.

The Knicks are entering this game with an 18-7 record overall this season and they are 4-6 in their road games this season, but they will be at a neutral site for this game. They are entering this game on a 5 game winning streak with wins coming against the Charlotte Hornets, the Utah Jazz, the Orlando Magic, the Toronto Raptors, and the Magic again. Jalen Brunson led the team in points in that game with 40 while Karl-Anthony Towns was next on the team with 29 points. Jalen Brunson led the team in assists in that game with 8 while Mitchell Robinson led the team in rebounds with 9. They were 60.7% from the field, 35% from 3-point range, and 74.2% from the free throw line with their shots in that game. Their offense is averaging 121 PPG and their defense is allowing their opponents to average 112.2 PPG against them. The Knicks have an ATS record of 17-8 this season and their O/U record is 13-12.

The current betting odds have the Spurs listed as a 2.5 point underdog in this game according to Draftkings Sportsbook. The Spurs have looked great in their games this season with their 18-7 record overall which has them right near the top of the West with one of the best records in the entire NBA. Meanwhile, the Knicks have looked great in their games this season with their 18-7 record overall which has them right near the top of the East with one of the best records in the entire NBA. This game is going to be at a neutral site in Las Vegas since this game is for the NBA Cup Finals. The Knicks have looked great lately as they are 9-1 in their last 10 games and they have a ton of momentum on their side with 5 wins in a row now. They blew out the Magic in the last round and took out the Raptors on the road the round before, but they have also had a much weaker path to this Final. The East as a whole looks like a much weaker conference this season and the Knicks didn't really have to get through a lot of elite teams to get here. The Spurs have had the tougher path and they have looked really good despite it. The Spurs are 7-3 in their last 10 games and they have also been rolling lately with 3 wins in a row now. They had to go on the road and beat a really good Lakers team in the Quarter-Finals, and now they have a ton of momentum on their side as they are off a win over the Thunder in the last round, handing the Thunder just their 2nd loss of the season. Wemby came back in that one too and he had a big impact on the game so he is going to make a big difference in this game. The best way to place a bet here is on the Spurs to cover the spread in this game. 

Spurs Knicks Prediction:  Our NBA Pick for Tuesday, December 16, 2025 (8:30 pm ET start time) is Spurs 122 Knicks 117.

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San Antonio Spurs: 14-7 ATS against Atlantic division opponents. 18-5 ATS when playing against a top-level team (Win Pct. > 70%). 35-24 ATS versus good teams - outscoring their opponents by 3+ points/game. 22-15 OVER off an upset win as an underdog.

New York Knicks: 10-18 ATS when playing against a top-level team (Win Pct. > 70%). 6-16 1H ATS against Southwest division opponents. 26-43 1H ATS when playing only their 2nd game in 5 days. 20-13 OVER in December games.

San Antonio Spurs:  None.

New York Knicks:  M. McBride (PG) Out - Ankle. L. Shamet (SG) Out - Shoulder.

“In a way it was the worst-case scenario for his first game back with the restrictions, and there’s just so much that he could not control or have a say-so. So it was going to be a little bit of a wild card, and I think for him, he just put himself into the game.” - Mitch Johnson on Wemby after his team’s win against the OKC Thunder in the NBA Cup Semi-Finals on Saturday.

“He makes the game easier for everybody. That’s what MVPs are supposed to do, and he definitely did that tonight. He scored for us when we didn’t have much going with our offensive movement and stuff like that. You have a guy like that that can go get a bucket and he keeps you in the game and gets you leads and at the end of the day, he carries you home.” - Mike Brown on Jalen Brunson after his team’s win against the Magic in the NBA Cup Semi-Finals on Saturday.

PG De'Aaron Fox

SG Stephon Castle

SF Devin Vassell

PF Harrison Barnes

C Victor Wembanyama

PG Jalen Brunson

SG Josh Hart

SF Mikal Bridges

PF OG Anunoby

C Karl-Anthony Towns

PPG: Victor Wembanyama (25.8)

APG: Stephon Castle (6.9)

Reb/G: Victor Wembanyama (12.6)

PPG: Jalen Brunson (28.8)

APG: Jalen Brunson (6.4)

Reb/G: Karl-Anthony Towns (11.9)

Coaches:

San Antonio Spurs: Mitch Johnson (2nd season)

New York Knicks: Mike Brown (1st season)