Purdue Boilermakers vs Iowa Hawkeyes Prediction, Picks and Game Preview - 11/14/2026

Game Time: 7:30 pm ET, Saturday, November 14, 2026

Venue:  Kinnick Stadium, Iowa City, IA

Where to Watch:  NBC

DraftKings:  Point Spread:  Purdue +17.5, Iowa -17.5; Over/Under:  47.5 points

Bet365:  Point Spread:  Purdue +17.5, Iowa -17.5; Over/Under:  47.5 points

BetMGM:  Point Spread:  Purdue +17, Iowa -17; Over/Under:  47.5 points

Purdue Boilermakers:  3-6 (2-4) (15th place, Big Ten)

Iowa Hawkeyes:  7-2 (4-2) (5th place, Big Ten)

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Purdue Boilermakers:  lost their last game at home against the Maryland Terrapins 34-29.

Iowa Hawkeyes:  won their last game on the road against the Northwestern Wildcats 24-10.

Purdue is entering this game with a 3-6 record overall and they have a 2-4 record in their conference games too. They are 2-4 in their home games, 1-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against Maryland 34-29. Ryan Browne was the starting QB and he completed 24/38 passes for 296 passing yards, 0 touchdowns, and 0 interceptions. Antonio Harris led the team in rushing yards with 51. Tra'Mar Harris led the receivers with 76 receiving yards on 3 receptions. Jojo Hayden led the defense in that game with 8 tackles while C.J. Madden led the defense in sacks with 1. Trey Smith came away with the only interception for them in that one.

 

 

 

Iowa is entering this game with a 7-2 record overall and they have a 4-2 record in their conference games too. They are 4-1 in their home games, 3-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against Northwestern 24-10. Hank Brown was the starting QB and he completed 16/21 passes for 126 passing yards, 1 touchdown, and 1 interception. L.J. Phillips Jr. led the team in rushing yards with 128. Tony Diaz led the receivers with 43 receiving yards on 2 receptions and 1 TD. Cam Buffington led the defense in that game with 12 tackles while Jayden Montgomery, Bryce Hawthorne, Luke Gaffney, Drew Campbell, Iose Epenesa, and Kenneth Merrieweather each led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.

The current betting odds have Iowa listed as a 17.5 point favorite in this game according to Draftkings Sportsbook. Iowa has looked good in their games this season with their 7-2 record overall and their 4-2 conference record which has them in the top half of the Big Ten. They have looked great on their home field too with their 4-1 home record this season. Meanwhile, Purdue hasn't looked good in their games this season with their 3-6 record overall and their 2-4 conference record which has them in the bottom half of the Big Ten. They haven't been a great road team either with their 1-2 road record this year. Purdue had a good start to the season and they looked like they were going to turn things around. They have had some tight games against some really good opponents and their offense has been putting up points, but their defense still hasn't looked great all year and now the wheels are starting to come off for them. They are coming off a 34-29 home loss to a bad Maryland team in their last one and they haven't looked that good lately with a rough stretch of games. Iowa has been one of the best teams in the Big Ten all season and they aren't going to overlook Purdue here with a chance to make the CFP if things fall their way. They are coming off a 24-10 road win over Northwestern in their last one and they have been rolling over a lot of the bad teams in the conference. They have one of the best defenses in the Big Ten that doesn't give up many points, but they also have a much better offense this season that has been scoring and that is a tough combination for this Purdue team to beat on the road when things have already been going sour. The best way to place a bet here is on Iowa to cover the spread in this game. 

Purdue Iowa Prediction:  Our NCAAF Pick for Saturday, November 14, 2026 (7:30 pm ET start time) is Iowa 35 Purdue 10.

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Purdue Boilermakers: 9-20 ATS against FBS division opponents. 4-14 ATS off a loss against a conference rival. 4-9 ATS vs. good teams - outscoring opponents by 10+ PPG on the season. 4-1 UNDER after a loss by 6 or less points. 3-0 UNDER off an upset loss to a conference rival as a home favorite.

Iowa Hawkeyes: 21-12 ATS in all lined games. 16-9 ATS as a favorite. 16-7 ATS against conference opponents. 7-2 ATS vs. good passing teams averaging 250 or more passing yards/game. 11-3 UNDER when the total is between 42.5 and 49. 5-2 UNDER off a road win against a conference rival.

Purdue Boilermakers:  K. Fox (TE) Out - Knee.

Iowa Hawkeyes:  H. Brown (QB) Out - Shoulder. L. Phillips Jr. (RB) Questionable - Ankle.

“It's devastating. We understand what we need to do and the urgency to get it done. We're not near as consistent enough as we need to be to win." - Barry Odom after his team’s loss against Maryland in their last game. 

“Just doing the good things, whether it's fourth-down stops or driving the ball and then putting it in the end zone. That's how you build confidence. You can't give it to them. Doing it in practice is a start, but doing it in game competition against good teams, it's a good thing. Hopefully what they'll take from this is they have to do it every week.” - Kirk Ferentz after his team’s win against Northwestern in their last game. 

WR Morrissette, De'Nylon

WR Magwood, Chauncey

WR Townsend, Xavier

TE Burhenn, George

QB Browne, Ryan

RB Ijeboi, Fame

WR Vander Zee, Reece 

WR Diaz, Tony

WR James, Evan

TE Vonnahme, DJ

QB Brown, Hank

RB Phillips Jr., L.J.

Passing: Ryan Browne (2,260)

Rushing: Fame Ijeboi (620)

Receiving: Asaad Waseem (709)

Touchdowns: Fame Ijeboi (11)

Passing: Hank Brown (1,316)

Rushing: Kamari Moulton (541)

Receiving: Tony Diaz (504)

Touchdowns: Xavier Williams (4)

Coaches:

Purdue Boilermakers: Barry Odom (2nd season)

Iowa Hawkeyes: Kirk Ferentz (28th season)