Portland Trail Blazers vs Los Angeles Lakers Prediction, Preview and Odds - 11/06/2026

by Rod Pearson

Thursday, Nov 05, 2026
Game Time: 10:00 pm ET, Friday, November 6, 2026
Venue:  Crypto.com Arena, Los Angeles, CA
Where to Watch:  Prime Video


Opening Odds at USA Sportsbooks

DraftKings:  Point Spread:  Trail Blazers +2.5, Lakers -2.5; Over/Under:  231.5 points
Bet365:  Point Spread:  Trail Blazers +2.5, Lakers -2.5; Over/Under:  231.5 points
BetMGM:  Point Spread:  Trail Blazers +2.5, Lakers -2.5; Over/Under:  231.5 points

Season Record

Portland Trail Blazers:  6-1 (1st place, Northwest Division)
Los Angeles Lakers:  7-2 (1st place, Pacific Division)

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Recent Form
Portland Trail Blazers:  6-1 last 7
Los Angeles Lakers:  7-2 last 9


Portland Trail Blazers vs Los Angeles Lakers Preview and Analysis


The Trail Blazers are entering this game with a 6-1 record overall this season and they are 5-0 in their road games this season where they will be in this game. They are entering this game on a 3 game winning streak with wins coming against the Utah Jazz, the Denver Nuggets, and the Phoenix Suns. Damian Lillard led the team in points in that game with 25 while Donovan Clingan was next on the team with 24 points. Deni Avdija led the team in assists in that game with 12 while Donovan Clingan led the team in rebounds with 11. They were 51.2% from the field, 35.9% from 3-point range, and 73.2% from the free throw line with their shots in that game. Their offense is averaging 121.9 PPG and their defense is allowing their opponents to average 110.7 PPG against them. The Trail Blazers have an ATS record of 5-2 this season and their O/U record is 3-4.



The Lakers are entering this game with a 7-2 record overall this season and they are 4-1 in their home games this season where they will be in this game. They are entering this game on a 3 game winning streak with wins coming against the Toronto Raptors, the Miami Heat, and the Sacramento Kings. Luka Dončić led the team in points in that game with 40 while Austin Reaves was next on the team with 21 points. Luka Dončić led the team in assists in that game with 7 while Luka Dončić led the team in rebounds with 9. They were 44.9% from the field, 31.6% from 3-point range, and 89.5% from the free throw line with their shots in that game. Their offense is averaging 121.8 PPG and their defense is allowing their opponents to average 113.9 PPG against them. The Lakers have an ATS record of 6-3 this season and their O/U record is 5-4.


Trail Blazers vs Lakers Prediction

The current betting odds have the Lakers listed as a 2.5 point favorite in this game according to Draftkings Sportsbook. The Lakers have looked great in their games this season with their 7-2 record overall which has them right near the top of the West with one of the best records in the entire NBA. They have looked great on their home court too with their 4-1 home record this season. Meanwhile, the Trail Blazers have looked great in their games this season with their 6-1 record overall which has them right at the top of the West with one of the best records in the entire NBA. They have been a great road team too with their 5-0 road record this year. The Trail Blazers have been rolling to start the season with their new head coach and he has them on the right path. They have a lot of momentum right now with 3 wins in a row and they are still undefeated on the road too, but that isn't going to last much longer. They have been crushing opponents in a lot of their games and haven't been giving up many points, but they have also had a weaker schedule to start the season and have been beating up on a lot of bad teams. The Lakers have had a much tougher schedule so far with more challenges early on and they have been rolling right through it too. They have a lot of momentum on their side with 3 wins in a row now and they are going to bring their best effort here since they did lose their first game in the NBA Cup. They have to make up some ground here and Luka has looked like one of the best players in the NBA with how good he has been playing. The Lakers are still the more talented team here and they are going to be motivated to bounce back in this tournament, so look for them to bring their best effort here to knock the Trail Blazers down a peg from this hot start. The best way to place a bet here is on the Lakers to cover the spread in this game. 

Trail Blazers Lakers Prediction:  Our NBA Pick for Friday, November 6, 2026 (10:00 pm ET start time) is Lakers 120 Trail Blazers 112.
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NBA Betting Trends


Portland Trail Blazers: 24-16 ATS against Pacific division opponents. 46-30 ATS when the total is greater than or equal to 230. 23-16 ATS versus teams who average 9 or more steals/game on the season. 11-6 UNDER as a road underdog of 6 points or less. 

Los Angeles Lakers: 6-16 ATS when playing against a top-level team (Win Pct. > 70%). 20-27 ATS off a road win. 30-20 UNDER revenging a same season loss vs opponent. 

Key Injuries


Portland Trail Blazers:  V. Krejci (PG) Out - Leg. J. Morant (PG) Out - Hamstring. S. Sharpe (SG) Out - Meniscus.

Los Angeles Lakers:  A. Thiero (SF) Out - Knee.


Notable Quotes


“Most importantly, we got to the free throw line 41 times, and with that, we still had 29 assists. So the ball was moving. I felt that the way they had guys at the level and were putting two on the ball, we were moving it. Sometimes I felt like we even passed up some really good shots.” - Micah Nori after his team’s win against the Suns in their game on Wednesday.


"I think when the game started, we were a little flat. I called an early timeout. They had 16 points. They scored 87 for the last 43:27 seconds or whatever it was [after] I called that timeout. The promising thing on that side of the ball is the effort and the intent to execute, I think, is really high. Second efforts were really good. We had a number of veer switches and peel switches and scrambles, had a number of late shot clock possessions for them, some shot clock violations. We did a lot on that end. I think the activity overall was really good, save for the first four minutes or whatever it was." - JJ Redick after his team’s win against the Kings in their game on Wednesday.


Starting Lineups


Portland Trail Blazers
PG Damian Lillard
SG Scoot Henderson
SF Toumani Camara
PF Deni Avdija
C Donovan Clingan

Los Angeles Lakers
PG Luka Doncic
SG Austin Reaves
SF Ziaire Williams
PF Matisse Thybulle
C Walker Kessler

Statistical Leaders


Portland Trail Blazers
PPG: Deni Avdija (23.4)
APG: Deni Avdija (6.4)
Reb/G: Donovan Clingan (10.6)

Los Angeles Lakers
PPG: Luka Doncic (38.5)
APG: Luka Doncic (8)
Reb/G: Walker Kessler (10.2)

Coaches:
Portland Trail Blazers: Micah Nori (1st season)
Los Angeles Lakers: JJ Redick (3rd season)



Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

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