Pittsburgh Steelers vs Cincinnati Bengals Prediction, Preview and Odds - 10/16/2025

Game Time: 8:15 pm ET, Thursday, October 16, 2025

Venue:  Paycor Stadium, Cincinnati, OH

Where to Watch:  Prime Video

DraftKings:  Point Spread:  Steelers -5.5, Bengals +5.5; Over/Under:  43.5 points

Bet365:  Point Spread:  Steelers -5.5, Bengals +5.5; Over/Under:  43 points

BetMGM:  Point Spread:  Steelers -5.5, Bengals +5.5; Over/Under:  42.5 points

Pittsburgh Steelers:  4-1 (1st place, AFC North)

Cincinnati Bengals:  2-4 (2nd place, AFC North)

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Pittsburgh Steelers:  won their last game at home against the Cleveland Browns 23-9.

Cincinnati Bengals:  lost their last game on the road against the Green Bay Packers 27-18.

The Steelers are entering this game with a 4-1 record overall and they have a 1-0 record in their divisional games too. They are 1-1 in their home games, 2-0 in their road games, and they are also 1-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against the Cleveland Browns 23-9. Aaron Rodgers was the starting QB and he completed 21/30 passes for 235 passing yards, 2 touchdowns, and 0 interceptions. Jaylen Warren led the team in rushing yards with 52. DK Metcalf led the receivers with 95 receiving yards on 4 receptions and 1 TD. DeShon Elliott led the defense in that game with 4 solo tackles and 8 assisted tackles while Jalen Ramsey and Nick Herbig each led the defense in sacks with 2. No one on the defense came away with an interception for them in that one.

 

 

 

The Bengals are entering this game with a 2-4 record overall and they have a 1-0 record in their divisional games too. They are 1-1 in their home games, 1-3 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against the Green Bay Packers 27-18. Joe Flacco was the starting QB and he completed 29/45 passes for 219 passing yards, 2 touchdowns, and 0 interceptions. Chase Brown led the team in rushing yards with 42. Ja'Marr Chase led the receivers with 94 receiving yards on 10 receptions and 1 TD. Barrett Carter led the defense in that game with 7 solo tackles and 3 assisted tackles while Geno Stone led the defense in sacks with 1. Geno Stone came away with the only interception for them in that one.

The current betting odds have the Steelers listed as a 5.5 point favorite in this game according to Draftkings Sportsbook. The Steelers have looked great in their games this season with their 4-1 record overall which has them right at the top of the AFC North with the only winning record in the division. They are off a 23-9 win over the Browns in their last one and their defense has looked a lot better in their last few games than the way they started the season. Meanwhile, the Bengals haven't looked great in their games this season with their 2-4 record overall. They started the season 2-0 and were looking good, but they lost their starting QB Joe Burrow to injury and with that they have lost 4 games in a row now. They had one of the worst defenses in the NFL last season and their defense hasn't looked any better this year. Their offense has also been a disaster without Burrow starting. They did look a little better in their last game with Flacco taking over, but they still couldn't do much in that game and they are going to be facing another good defense here. The Steelers have a lot more consistency on both sides of the ball right now and the Bengals are the team right behind them in the division so they are going to bring their best effort to really get ahead in this division. The best way to place a bet here is on the Steelers to cover the spread in this game. 

Steelers Bengals Prediction:  Our NFL Pick for Thursday, October 16, 2025 (8:15 pm ET start time) is Steelers 24 Bengals 13.

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Pittsburgh Steelers: 24-17 ATS in all games. 6-2 ATS when playing against a bad team (Win Pct. 25% to 40%). 8-4 ATS versus poor defensive teams - allowing 5.65 yards/play or more. 4-1 OVER after 3 or more consecutive wins against the spread. 6-2 OVER when playing against a bad team (Win Pct. 25% to 40%).

Cincinnati Bengals: 5-9 ATS as an underdog. 4-9 ATS versus division opponents. 2-8 ATS off a road loss. 1-4 ATS against teams with a turnover margin of +1 per game or better. 24-15 OVER in all games. 10-3 OVER in a home game where the total is between 42.5 and 49 points. 12-5 OVER when playing against a team with a winning record.

Pittsburgh Steelers:  A. Rodgers (QB) Injured - NIR - Rest. M. Killebrew (S) Injured - Knee. D. Metcalf (WR) Injured - NIR - Rest. D. Slay (CB) Injured - NIR - Rest. J. Ramsey (CB) Injured - NIR - Rest. C. Heyward (DL) Injured - NIR - Rest. T. Watt (LB) Injured - NIR - Rest. C. Austin III (WR) Injured - Shoulder.

Cincinnati Bengals:  None.

“Why is it starting to look the way that we desire? We got a full complement of talent. When we put this band together, we feel like we can do the things you saw today.” - Mike Tomlin after his team’s win against the Browns in their last game. 

“We gave ourselves a chance down at the end, and we did some good things, but just not enough." - Joe Flacco after their loss against the Packers in their last game. 

WR Metcalf, DK

WR Wilson, Roman

TE Smith, Jonnu

TE Freiermuth, Pat 

QB Rodgers, Aaron

RB Warren, Jaylen

WR Chase, Ja'Marr

WR Higgins, Tee

WR Iosivas, Andrei

TE Sample, Drew

QB Flacco, Joe

RB Brown, Chase

Passing: Aaron Rodgers (1,021)

Rushing: Jaylen Warren (184)

Receiving: DK Metcalf (356)

Touchdowns: DK Metcalf (4)

Passing: Jake Browning (757)

Rushing: Chase Brown (202)

Receiving: Ja'Marr Chase (468)

Touchdowns: Ja'Marr Chase (4)

Coaches:

Pittsburgh Steelers: Mike Tomlin (19th season)

Cincinnati Bengals: Zac Taylor (7th season)