Philadelphia Phillies vs Washington Nationals Prediction, Preview and Odds - 06/25/2026

Game Time: 6:45 pm ET, Thursday, June 25, 2026

Venue:  Nationals Park, Washington, DC

Where to Watch:  MLB TV

DraftKings:  Moneyline odds:  Phillies -186, Nationals +153; Over/Under:  8 runs

Bet365:  Moneyline odds:  Phillies -185, Nationals +155; Over/Under:  8 runs

BetMGM:  Moneyline odds:  Phillies -185, Nationals +155; Over/Under:  8 runs

Philadelphia Phillies:  43-36 (2nd place, NL East)

Washington Nationals:  41-39 (4th place, NL East)

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Philadelphia Phillies:  6-4 last 10

Washington Nationals:  6-4 last 10

The Phillies are entering this series off a win and won their 3-game series against the New York Mets 2-1 in their last series. They enter this game with a 43-36 record overall and have a road record of 20-17. This is the series finale of a 4-game series with the Nationals on Thursday with the 3rd game still to be played on Wednesday. The Phillies lost the series opener on Monday and won the 2nd game on Tuesday. Their offense ranks 23rd in the MLB with a .701 OPS. Aaron Nola is their starting pitcher on Wednesday while Cristopher Sánchez is making his start in this game on Thursday. He is 9-3 with a 1.80 ERA this season. His team won 4 of their last 5 games this season with him making an appearance. In his last MLB regular season appearance, he allowed 1 ER, 1 HR, and 1 BB with 5 SO on 5 hits through 6 IP against the New York Mets.

The Nationals are entering this series off a loss and lost their 3-game series against the Tampa Bay Rays 2-1 in their last series. They enter this game with a 41-39 record overall and have a home record of 17-23. This is the 4th game of a 4-game series with the Phillies on Thursday with the 3rd game of this series still to be played on Wednesday. The Nationals won the 1st game of this series on Monday and lost the 2nd game on Tuesday. Their offense ranks 3rd in the MLB with a .745 OPS. Miles Mikolas is their starting pitcher on Wednesday while Cade Cavalli is making his start in this game on Thursday. He is 4-4 with a 4.07 ERA this season. His team won their last 2 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 2 earned runs, 0 homers, and 3 walks with 1 strikeout on 6 hits through 2.2 innings pitched against the Tampa Bay Rays.

The current betting odds have the Phillies listed as a favorite in this game according to Draftkings Sportsbook. The Phillies have looked good in their games this season with their 43-36 record overall which has them right near the top of the NL East. They have been a good road team too with their 20-17 road record this year. Meanwhile, the Nationals have looked good in their games this season with their 41-39 record overall, but that record has them right near the bottom of the NL East. They haven't looked great in their own ballpark too with their 17-23 home record this season. The Nationals are 6-4 in their last 10 games and they have one of the best offenses in MLB at the moment, but they have some big issues with their pitching staff giving up a lot of runs and that has been a common theme all season. The Phillies haven't had the best offense this season, but their offense has come to life in this series as they are starting to get hot, now 6-4 in their last 10 games. The Phillies are going with Sanchez in this one too and he has looked great this season. He is 9-3 with a 1.80 ERA and he has been their ace this year. He is coming off another great start in which he only gave up 1 earned run, something that has been a common theme for him all season, and the team has also had a ton of success with him lately, winning 4 of their last 5 games with him starting. The Nationals are going with Cavalli in this one and he hasn't looked great this year. He is 4-4 with a 4.07 ERA and he has been giving up quite a few runs all season. He only gave up 2 earned runs in his last start and the team has had more success with him lately, winning 2 games in a row now with him starting, but he isn't going to hold up with this Phillies offense getting hot now and he doesn't have a trustworthy bullpen to help him out either. This is a pitching matchup that the Phillies can take advantage of with their offense getting hot now and the Nationals have also been a worse home team this season. The best way to place a bet here is on the Phillies to win this game. 

Phillies Nationals Prediction:  Our MLB Pick for Thursday, June 25, 2026 (6:45 pm ET start time) is Phillies 6 Nationals 1.

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Philadelphia Phillies: 103-100 (-13.2 units) on the moneyline in road games. 109-104 (-12.6 units) on the moneyline when playing against a team with a winning record. 72-57 (-4.2 units) on the moneyline against division opponents. 16-11 OVER as a favorite of -150 or more.

Washington Nationals: 178-227 (+8.1 units) on the moneyline in all games. 141-186 (+21.8 units) on the moneyline as an underdog of +100 or higher. 54-67 (+8.7 units) on the moneyline against left-handed starters. 27-11 OVER in home games.

Philadelphia Phillies:  K. Schwarber (DH) Day To Day - Back. B. Keller (RP) Fifteen Day IL - Forearm. A. Garcia (RF) Sixty Day IL - Lat. 

Washington Nationals:  C. Abrams (SS) Day To Day - Side. M. Kranick (RP) Sixty Day IL - Elbow. J. Irvin (SP) Fifteen Day IL - Shoulder. K. Waldichuk (SP) Sixty Day IL - Forearm. J. Gray (SP) Sixty Day IL - Elbow. D. Herz (SP) Sixty Day IL - Elbow. T. Williams (SP) Sixty Day IL - Elbow.

“This game’s crazy when you see stuff like that.” - Don Mattingly on his team’s 9th inning comeback win against the Nationals on Tuesday. 

“About as frustrating of a loss as we’ve seen, as I’ve ever been a part of.” - Blake Butera after his team’s loss against the Phillies in their game on Tuesday. 

Trea Turner (R) SS

Brandon Marsh (L) LF

Bryce Harper (L) 1B

Alec Bohm (R) 3B

Bryson Stott (L) 2B

J.T. Realmuto (R) C

Gabriel Rincones Jr. (L) RF

Edmundo Sosa (R) DH

Justin Crawford (L) CF

James Wood (L) RF

Curtis Mead (R) 3B

Andrés Chaparro (R) 1B

Dylan Crews (R) LF

Jorbit Vivas (L) 2B

Jacob Young (R) CF

Nasim Nuñez (S) SS

José Tena (L) DH

Keibert Ruiz (S) C

Batting Average:  Brandon Marsh (.315)

Hits:  Brandon Marsh (85)

Home Runs:  Kyle Schwarber (29)

RBI:  Kyle Schwarber (52)

Stolen Bases:  Trea Turner (15)

Wins:  Cristopher Sánchez (9)

Saves:  Jhoan Duran (18)

ERA:  Bryse Wilson (0.00)

Batting Average:  CJ Abrams (.286)

Hits:  CJ Abrams (82)

Home Runs:  James Wood (20)

RBI:  CJ Abrams (57)

Stolen Bases:  Nasim Nuñez (31)

Wins:  Foster Griffin (8)

Saves:  Gus Varland (6)

ERA:  Julian Fernández (2.25)

Managers:

Philadelphia Phillies: Don Mattingly (Interim)

Washington Nationals: Blake Butera (1st season)