by Rod Pearson
Tuesday, Sep 16, 2025
Game Time: 10:10 pm ET, Wednesday, September 17, 2025
Venue: Dodger Stadium, Los Angeles, CA
Where to Watch: MLBN
Opening Odds at USA Sportsbooks
DraftKings: Moneyline odds: Phillies +123, Dodgers -150; Over/Under: 7.5 runs
Bet365: Moneyline odds: Phillies +125, Dodgers -150; Over/Under: 7.5 runs
BetMGM: Moneyline odds: Phillies +125, Dodgers -150; Over/Under: 7.5 runs
Season Record
Philadelphia Phillies: 90-61 (1st place, NL East)
Los Angeles Dodgers: 84-66 (1st place, NL West)
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Recent Form
Philadelphia Phillies: 8-2 last 10
Los Angeles Dodgers: 6-4 last 10
Philadelphia Phillies vs Los Angeles Dodgers Preview and Analysis
The Phillies are entering this series off a loss and won their 3-game series against the Kansas City Royals 2-1 in their last series. They enter this game with a 90-61 record overall and have a road record of 39-37. This is the series finale of a 3-game series with the Dodgers on Wednesday with the 2nd game still to be played on Tuesday. The Phillies won the series opener on Monday. Their offense ranks 4th in the MLB with a .763 OPS. Cristopher Sánchez is their starting pitcher on Tuesday while Jesús Luzardo is making his start in this game on Wednesday. He is 14-6 with a 4.03 ERA this season. His team won their last 2 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 4 ER, 0 HR, and 0 BB with 10 SO on 5 hits through 8 IP against the New York Mets.
The Dodgers are entering this series off a win and won their 3-game series against the San Francisco Giants 2-1 in their last series. They enter this game with an 84-66 record overall and have a home record of 48-27. This is the 3rd game of a 3-game series with the Phillies on Wednesday with the 2nd game of this series still to be played on Tuesday. The Dodgers lost the 1st game of this series on Monday. Their offense ranks 2nd in the MLB with a .769 OPS. Shohei Ohtani is their starting pitcher on Tuesday while Blake Snell is making his start in this game on Wednesday. He is 4-4 with a 2.79 ERA this season. His team lost 3 of their last 4 games this season with him making an appearance. In his last MLB regular season start, he allowed 0 earned runs, 0 homers, and 2 walks with 11 strikeouts on 2 hits through 6 innings pitched against the Colorado Rockies.
Phillies vs Dodgers Prediction
The current betting odds have the Dodgers listed as a favorite in this game according to Draftkings Sportsbook. The Phillies have looked great in their games this season with their 90-61 record overall which has them right at the top of the NL East with one of the best records in the entire MLB. They haven't been a bad road team either with their 39-37 road record this year. Meanwhile, the Dodgers have looked great in their games this season with their 84-66 record overall which has them right at the top of the NL West. They have looked great in their own ballpark too with their 48-27 home record this season. Both of these teams have been hot lately, the Phillies going 8-2 in their last 10 games while the Dodgers are 6-4, but the Dodgers do have the better pitching matchup in this one to take advantage of. They are going with Snell in this one and he has looked great this season. He is 4-4 with a 2.79 ERA and he hasn't been giving up many runs lately. His team has struggled with him starting lately, losing 3 of the last 4 games he started in, but he gave up no runs in his last start and that has been a common theme for him. The Dodgers are going to bring their best effort for this series too since they are chasing down the Phillies in the NL. The Phillies are going with Luzardo in this one and he hasn't been great this season. He is 14-6 with a 4.03 ERA and has been giving up a lot more runs lately. His team has been having success with him lately, winning 2 games in a row now with him starting, but he did give up 4 earned runs in his last start and that has been a common theme for him lately. The Dodgers are also going to be really motivated to finish this series strong after losing the opener on Monday. The best way to place a bet here is on the Dodgers to win this game.
Phillies Dodgers Prediction: Our MLB Pick for Wednesday, September 17, 2025 (10:10 pm ET start time) is Dodgers 6 Phillies 2.
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MLB Betting Trends
Philadelphia Phillies: 62-39 (+12 units) on the moneyline against NL West opponents. 285-208 (+14 units) on the moneyline in all games. 60-40 (+9.3 units) on the moneyline vs. a starting pitcher whose gives up 0.5 or less HR's/start. 14-5 UNDER as a road underdog of +100 to +150.
Los Angeles Dodgers: 293-200 (-14.6 units) on the moneyline in all games. 86-64 (-15.1 units) on the moneyline against left-handed starters. 132-107 (-9.9 units) on the moneyline when playing against a team with a winning record. 35-19 UNDER when the money line is -100 to -150.
Key Injuries
Philadelphia Phillies: E. Sosa (2B) Day To Day - Groin. J. Alvarado (RP) Fifteen Day IL - Forearm. A. Bohm (3B) Ten Day IL - Shoulder. T. Turner (SS) Ten Day IL - Hamstring. D. Robert (RP) Sixty Day IL - Forearm. Z. Wheeler (SP) Sixty Day IL - Blood Clot. J. Romano (RP) Fifteen Day IL - Finger.
Los Angeles Dodgers: W. Smith (C) Ten Day IL - Hand. D. Rushing (C) Ten Day IL - Shin. B. Stewart (RP) Fifteen Day IL - Shoulder. R. Sasaki (SP) Sixty Day IL - Shoulder. T. Gonsolin (SP) Sixty Day IL - Elbow. E. Phillips (RP) Sixty Day IL - forearm. K. Hurt (SP) Sixty Day IL - Elbow. M. Grove (RP) Sixty Day IL - Shoulder. B. Graterol (RP) Sixty Day IL - Shoulder. R. Ryan (SP) Sixty Day IL - Elbow. G. Stone (SP) Sixty Day IL - Shoulder.
Notable Quotes
“We keep pushing, we keep grinding. It’s a lot of the same faces, right? Everyone knows and expects what we expect out of each other. I think that’s the great thing. We expect a lot out of ourselves.” - Kyle Schwarber after their win against the LA Dodgers in their game on Monday.
“Emmet’s a guy that’s just unfazed by anything. He’s in a great spot for a young-ish player. He’s very mature and very confident.” - Dave Roberts after his team’s loss against the Phillies in their game on Monday.
Starting Lineups
Philadelphia Phillies
Harrison Bader (R) CF
Kyle Schwarber (L) DH
Bryce Harper (L) 1B
J.T. Realmuto (R) C
Brandon Marsh (L) LF
Otto Kemp (R) 3B
Max Kepler (L) RF
Bryson Stott (L) SS
Weston Wilson (R) 2B
Los Angeles Dodgers
Shohei Ohtani (L) DH
Mookie Betts (R) SS
Teoscar Hernández (R) RF
Freddie Freeman (L) 1B
Alex Call (R) LF
Miguel Rojas (R) 2B
Max Muncy (L) 3B
Andy Pages (R) CF
Chuckie Robinson (R) C
Statistical Leaders
Philadelphia Phillies
Batting Average: Harrison Bader (.338)
Hits: Trea Turner (179)
Home Runs: Kyle Schwarber (53)
RBI: Kyle Schwarber (128)
Stolen Bases: Trea Turner (36)
Wins: Jesús Luzardo (14)
Saves: Jhoan Duran (14)
ERA: Lou Trivino (1.59)
Los Angeles Dodgers
Batting Average: Ben Rortvedt (.308)
Hits: Shohei Ohtani (159)
Home Runs: Shohei Ohtani (49)
RBI: Shohei Ohtani (93)
Stolen Bases: Shohei Ohtani (19)
Wins: Yoshinobu Yamamoto (11)
Saves: Tanner Scott (21)
ERA: Evan Phillips (0.00)
Managers:
Philadelphia Phillies: Rob Thomson (4th season)
Los Angeles Dodgers: Dave Roberts (10th season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
