by Rod Pearson
Tuesday, Sep 16, 2025
Game Time: 10:10 pm ET, Tuesday, September 16, 2025
Venue: Dodger Stadium, Los Angeles, CA
Where to Watch: TBS
Opening Odds at USA Sportsbooks
DraftKings: Moneyline odds: Phillies +108, Dodgers -132; Over/Under: 7.5 runs
Bet365: Moneyline odds: Phillies +105, Dodgers -125; Over/Under: 7.5 runs
BetMGM: Moneyline odds: Phillies +105, Dodgers -125; Over/Under: 7.5 runs
Season Record
Philadelphia Phillies: 89-61 (1st place, NL East)
Los Angeles Dodgers: 84-65 (1st place, NL West)
Do not miss out on our expert handicapper analysis! Amedeus Mastrangelo is on a HOT STREAK in the MLB on a 12-4 MLB RUN for +$8,740 PROFIT! Make sure you check out his picks and many more from the expert handicappers featured in the Shop Picks section.
Recent Form
Philadelphia Phillies: 8-2 last 10
Los Angeles Dodgers: 6-4 last 10
Philadelphia Phillies vs Los Angeles Dodgers Preview and Analysis
The Phillies are entering this series off a loss and won their 3-game series against the Kansas City Royals 2-1 in their last series. They enter this game with an 89-61 record overall and have a road record of 38-37. This is the 2nd game of a 3-game series with the Dodgers on Tuesday with the series opener still to be played on Monday. Their offense ranks 4th in the MLB with a .763 OPS. Ranger Suárez is their starting pitcher on Monday while Cristopher Sánchez is making his start in this game on Tuesday. He is 13-5 with a 2.57 ERA this season. His team won their last 3 straight games this season with him making an appearance. In his last MLB regular season appearance, he allowed 1 ER, 0 HR, and 1 BB with 6 SO on 4 hits through 6 IP against the New York Mets.
The Dodgers are entering this series off a win and won their 3-game series against the San Francisco Giants 2-1 in their last series. They enter this game with an 84-65 record overall and have a home record of 48-26. This is the 2nd game of a 3-game series with the Phillies on Tuesday with the 1st game of this series still to be played on Monday. Their offense ranks 3rd in the MLB with a .768 OPS. Emmet Sheehan is their starting pitcher on Monday while Shohei Ohtani is making his start in this game on Tuesday. He is 1-1 with a 3.75 ERA this season. His team lost 5 of their last 6 games this season with him making an appearance. In his last MLB regular season start, he allowed 0 earned runs, 0 homers, and 1 walk with 5 strikeouts on 3 hits through 3.2 innings pitched against the Baltimore Orioles.
Phillies vs Dodgers Prediction
The current betting odds have the Phillies listed as a slight underdog in this game according to Draftkings Sportsbook. The Phillies have looked great in their games this season with their 89-61 record overall which has them right at the top of the NL East with one of the best records in the entire MLB. They haven't been a bad road team either with their 38-37 road record this year. Meanwhile, the Dodgers have looked great in their games this season with their 84-65 record overall which has them right at the top of the NL West. They have looked great in their own ballpark too with their 48-26 home record this season. The Dodgers have also been hot lately, going 6-4 in their last 10 games, but the Phillies have been hotter as they are 8-2 in their last 10 and they can take advantage of this pitching matchup too. The Phillies are going with Sanchez in this one and he has looked great this season. He is 13-5 with a 2.57 ERA and he hasn't been giving up many runs lately. He only gave up 1 earned run in his last start and the team has had a ton of success too, winning 3 games in a row now with him starting. The Dodgers are going with Ohtani in this one and he hasn't looked great this season. He is 1-1 with a 3.75 ERA and wasn't pitching for a lot of the season due to injury. He gave up no runs in his last start, but that hasn't been a common theme lately. The team has also been struggling with him on the mound, losing 5 of their last 6 games with him starting. The Phillies are rolling right now and this is a big series for them to try to catch the Brewers to win the NL. The best way to place a bet here is on the Phillies to win this game.
Phillies Dodgers Prediction: Our MLB Pick for Tuesday, September 16, 2025 (10:10 pm ET start time) is Phillies 3 Dodgers 2.
Don't miss our champion handicappers free picks, best bets, and expert baseball picks today. And if you enjoyed this Philadelphia Phillies Los Angeles Dodgers prediction, be sure to drop by every day for our daily MLB projections and previews.
MLB Betting Trends
Philadelphia Phillies: 61-39 (+11 units) on the moneyline against NL West opponents. 284-208 (+13 units) on the moneyline in all games. 197-136 (+19.4 units) on the moneyline against right-handed starters. 22-14 OVER vs. good power teams - averaging 1.25 or more HR's/game.
Los Angeles Dodgers: 293-199 (-13.4 units) on the moneyline in all games. 86-63 (-13.9 units) on the moneyline against left-handed starters. 132-106 (-8.7 units) on the moneyline when playing against a team with a winning record. 37-17 OVER vs. an NL starting pitcher whose ERA is 3.20 or better.
Key Injuries
Philadelphia Phillies: E. Sosa (2B) Day To Day - Groin. J. Alvarado (RP) Fifteen Day IL - Forearm. A. Bohm (3B) Ten Day IL - Shoulder. T. Turner (SS) Ten Day IL - Hamstring. D. Robert (RP) Sixty Day IL - Forearm. Z. Wheeler (SP) Sixty Day IL - Blood Clot. J. Romano (RP) Fifteen Day IL - Finger.
Los Angeles Dodgers: W. Smith (C) Ten Day IL - Hand. D. Rushing (C) Ten Day IL - Shin. B. Stewart (RP) Fifteen Day IL - Shoulder. R. Sasaki (SP) Sixty Day IL - Shoulder. T. Gonsolin (SP) Sixty Day IL - Elbow. E. Phillips (RP) Sixty Day IL - forearm. K. Hurt (SP) Sixty Day IL - Elbow. M. Grove (RP) Sixty Day IL - Shoulder. B. Graterol (RP) Sixty Day IL - Shoulder. R. Ryan (SP) Sixty Day IL - Elbow. G. Stone (SP) Sixty Day IL - Shoulder.
Notable Quotes
"It would have been nice to win a game at home to clinch it, but it didn't happen. So, we've just got to move on." - Rob Thomson after his team’s loss against the Royals in their game on Sunday.
"We've put ourselves in a tough spot. I still think, honestly, we just got to win games. If it happens, great. If it doesn't, great." - Dave Roberts after his team’s win against the Giants in their game on Sunday.
Starting Lineups
Philadelphia Phillies
Harrison Bader (R) CF
Kyle Schwarber (L) DH
Bryce Harper (L) 1B
J.T. Realmuto (R) C
Nick Castellanos (R) RF
Brandon Marsh (L) LF
Otto Kemp (R) 3B
Bryson Stott (L) SS
Weston Wilson (R) 2B
Los Angeles Dodgers
Shohei Ohtani (L) DH
Mookie Betts (R) SS
Teoscar Hernández (R) RF
Freddie Freeman (L) 1B
Tommy Edman (S) CF
Alex Call (R) LF
Miguel Rojas (R) 2B
Enrique Hernández (R) 3B
Ben Rortvedt (L) C
Statistical Leaders
Philadelphia Phillies
Batting Average: Harrison Bader (.349)
Hits: Trea Turner (179)
Home Runs: Kyle Schwarber (52)
RBI: Kyle Schwarber (127)
Stolen Bases: Trea Turner (36)
Wins: Jesús Luzardo (14)
Saves: Jhoan Duran (14)
ERA: Jhoan Duran (1.15)
Los Angeles Dodgers
Batting Average: Ben Rortvedt (.320)
Hits: Shohei Ohtani (158)
Home Runs: Shohei Ohtani (49)
RBI: Shohei Ohtani (93)
Stolen Bases: Shohei Ohtani (18)
Wins: Yoshinobu Yamamoto (11)
Saves: Tanner Scott (21)
ERA: Evan Phillips (0.00)
Managers:
Philadelphia Phillies: Rob Thomson (4th season)
Los Angeles Dodgers: Dave Roberts (10th season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
