Philadelphia 76ers vs New York Knicks Prediction, Preview and Odds - 05/04/2026

Game Time: 8:00 pm ET, Monday, May 4, 2026

Venue:  Madison Square Garden, New York, NY

Where to Watch:  NBC, Peacock

DraftKings:  Point Spread:  76ers +7.5, Knicks -7.5; Over/Under:  212.5 points

Bet365:  Point Spread:  76ers +7.5, Knicks -7.5; Over/Under:  212.5 points

BetMGM:  Point Spread:  76ers +7.5, Knicks -7.5; Over/Under:  211.5 points

Philadelphia 76ers:  45-37 (4th place, Atlantic Division)

New York Knicks:  53-29 (2nd place, Atlantic Division)

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Philadelphia 76ers:  7-3 last 10

New York Knicks:  7-3 last 10

The 76ers are entering the playoffs with a 45-37 record overall this season and they were 22-19 in their road games where they will be in this game. They are entering this game on a 3 game winning streak with wins coming against the Boston Celtics 3 times in a row. Joel Embiid led the team in points in that game with 34 while Tyrese Maxey was next on the team with 30 points. Tyrese Maxey led the team in assists in that game with 7 while Joel Embiid led the team in rebounds with 12. They were 47.6% from the field, 39.3% from 3-point range, and 87% from the free throw line with their shots in that game. Their offense is averaging 115.9 PPG and their defense is allowing their opponents to average 116.1 PPG against them. The 76ers have an ATS record of 49-41 this season and their O/U record is 42-48.

The Knicks are entering the playoffs with a 53-29 record overall this season and they were 30-10 in their home games where they will be in this game. They are entering this game on a 3 game winning streak with wins coming against the Atlanta Hawks 3 times in a row. OG Anunoby led the team in points in that game with 29 while Mikal Bridges was next on the team with 24 points. Karl-Anthony Towns led the team in assists in that game with 10 while Karl-Anthony Towns led the team in rebounds with 11. They were 58.8% from the field, 36.1% from 3-point range, and 79.4% from the free throw line with their shots in that game. Their offense is averaging 116.5 PPG and their defense is allowing their opponents to average 110.1 PPG against them. The Knicks have an ATS record of 48-41 this season and their O/U record is 41-48.

The current betting odds have the Knicks listed as a 7.5 point favorite in this game according to Draftkings Sportsbook. The Knicks have looked great in their games this season with their 53-29 record overall which had them right near the top of the East. They have looked great on their home court too with their 30-10 home record this season. Meanwhile, the 76ers have looked good in their games this season with their 45-37 record overall which had them right in the middle of the East. They have been a good road team too with their 22-19 road record this year. This is game 1 of a 7-game series between the 3 seeded Knicks and the 7 seeded 76ers in the East for the 2nd round of the NBA playoffs. The 76ers have been rolling lately as they are 7-3 in their last 10 games and they have a ton of momentum on their side now with 3 wins in a row. They were down 3-1 in their series against the 2 seeded Celtics and they looked dead in the water with Embiid looking terrible in his 1st game back from injury, but the 76ers rebounded from that loss and went on a 3 game winning streak to come back and kick the Celtics out of the playoffs. They did catch a break in game 7 though, the Celtics missing Tatum in that one, and they still haven't looked great in their road games for a lot of the season. The Knicks also have a ton of momentum on their side with 3 wins in a row now. They were down 2-1 in their series against the Hawks, but they stepped up big in the last 3 games and crushed the Hawks by over 20 points in all 3 games. As good as the 76ers looked in that last series to come back against what looked like the best team in the East, they have still had a lot of trouble with the Knicks in the last 2 meetings and the Knicks have looked like a different team on their home court. The Knicks are rolling right now and they will be looking to set the tone for this series in this 1st home game. The best way to place a bet here is on the Knicks to cover the spread in this game. 

76ers Knicks Prediction:  Our NBA Pick for Monday, May 4, 2026 (8:00 pm ET start time) is Knicks 114  76ers 104.

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Philadelphia 76ers: 5-9 ATS off a road win against a division rival. 16-25 ATS versus good offensive teams - scoring 116+ points/game. 22-28 ATS when playing against a team with a winning record. 27-17 UNDER as an underdog. 9-1 UNDER revenging a blowout loss vs opponent of 20 points or more.

New York Knicks: 16-6 ATS after successfully covering the spread in 3 or more consecutive games. 9-3 ATS as a home favorite of 6.5 to 12 points. 16-6 ATS after allowing 100 points or less. 6-3 UNDER in a home game where the total is 210 to 219.5. 29-22 UNDER when playing against a team with a winning record.

Philadelphia 76ers:  None.

New York Knicks:  None.

“We had a chance to beat them three years ago, didn’t do it. We came in and got it done." - Tyrese Maxey after their win against the Celtics in game 7 of that series on Saturday. 

“It’s tough because when you’re up that big, stuff happens. If somebody feels like something that shouldn’t happen to them happened, it’s hard to keep your composure in that moment.” - Mike Brown after his team’s win against the Hawks in game 6 of that series on Saturday. 

PG Tyrese Maxey

SG VJ Edgecombe

SF Kelly Oubre Jr.

PF Paul George

C Joel Embiid

PG Jalen Brunson

SG Josh Hart

SF Mikal Bridges

PF OG Anunoby

C Karl-Anthony Towns

PPG: Tyrese Maxey (28.3)

APG: Tyrese Maxey (6.6)

Reb/G: Andre Drummond (8.4)

PPG: Jalen Brunson (26)

APG: Jalen Brunson (6.8)

Reb/G: Karl-Anthony Towns (11.9)

Coaches:

Philadelphia 76ers: Nick Nurse (3rd season)

New York Knicks: Mike Brown (1st season)