Oregon State Beavers vs Oregon Ducks Prediction, Picks and Game Preview - 09/20/2025

by Rod Pearson

Monday, Sep 15, 2025
Game Time: 3:00 pm ET, Saturday, September 20, 2025
Venue:  Autzen Stadium, Eugene, OR
Where to Watch:  FOX


Opening Odds at USA Sportsbooks

DraftKings:  Point Spread:  OR State +35.5, Oregon -35.5; Over/Under:  57.5 points
Bet365:  Point Spread:  OR State +35, Oregon -35; Over/Under:  57.5 points
BetMGM:  Point Spread:  OR State +35.5, Oregon -35.5; Over/Under:  57.5 points

Season Record

Oregon State Beavers:  0-3 (0-0) (2nd place, Pac-12)
Oregon Ducks:  3-0 (1-0) (2nd place, Big Ten)

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Recent Form
Oregon State Beavers:  lost their last game on the road against the Texas Tech Red Raiders 45-14.
Oregon Ducks:  won their last game on the road against the Northwestern Wildcats 34-14.


Oregon State Beavers vs Oregon Ducks Preview and Analysis


Oregon State is entering this game with a 0-3 record overall and they have a 0-0 record in their conference games too. They are 0-2 in their home games, 0-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against Texas Tech 45-14. Maalik Murphy was the starting QB and he completed 24/43 passes for 278 passing yards, 2 touchdowns, and 2 interceptions. Anthony Hankerson led the team in rushing yards with 12. David Wells Jr. led the receivers with 103 receiving yards on 6 receptions. Dexter Foster led the defense in that game with 5 solo tackles and 5 assisted tackles while Tahjae Mullix led the defense in sacks with 1. Harlem Howard and Skyler Thomas each came away with 1 interception for them in that one.
 
 
 
Oregon is entering this game with a 3-0 record overall and they have a 1-0 record in their conference games too. They are 2-0 in their home games, 1-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against Northwestern 34-14. Dante Moore was the starting QB and he completed 16/20 passes for 178 passing yards, 1 touchdown, and 1 interception. Dierre Hill Jr. led the team in rushing yards with 94 and 1 TD. Malik Benson led the receivers with 62 receiving yards on 4 receptions. Aaron Flowers led the defense in that game with 2 solo tackles and 5 assisted tackles while Matayo Uiagalelei led the defense in sacks with 1. Jerry Mixon and Bryce Boettcher each came away with 1 interception for them in that one.


Oregon State vs Oregon Prediction

The current betting odds have Oregon listed as a 35.5 point favorite in this game according to Draftkings Sportsbook. Oregon has looked great in their games this season with their 3-0 record overall and their 1-0 conference record which has them right near the top of the Big Ten. They have looked great in all 3 games this season, putting up a ton of points on offense and their defense not giving much up either. They were supposed to take a step back this season with the talent they lost and their QB going to the NFL, but they are showing why they are still a threat to be one of the best teams in the Big Ten this year and maybe even the nation. Meanwhile, Oregon State has looked terrible in their games this season with their 0-3 record overall. They just lost to Texas Tech 45-14 last week and they are showing that they don't really have the talent to compete with the power 4 teams anymore. They are in a tough situation with their conference and it has been tough for them to bring in talent. Oregon just beat Northwestern in their last game 34-14 and it wasn't their best performance of the season, but it was also their first road game and their first conference game of the year. They have looked a lot better in their 2 home games though with bigger blowout wins and this home game will be no different against their rival. The best way to place a bet here is on Oregon to cover the spread in this game. 

Oregon State Oregon Prediction:  Our NCAAF Pick for Saturday, September 20, 2025 (3:00 pm ET start time) is Oregon 56 Oregon State 14.
Don't miss our champion handicappers free picks and expert football picks today. And if you enjoyed this Oregon State Beavers Oregon Ducks prediction, be sure to drop by every day for our weekly NCAAF predictions and previews.

NCAAF Betting Trends


Oregon State Beavers: 10-18 ATS in all lined games. 2-7 ATS as an underdog. 5-13 ATS in non-conference games. 3-7 ATS vs. good offensive  teams - scoring 31 or more points/game. 9-4 UNDER when the total is between 56.5 and 63. 7-4 UNDER in road lined games.

Oregon Ducks: 19-11 ATS in all lined games. 18-10 ATS as a favorite. 10-5 ATS after allowing 14 points or less last game. 6-3 UNDER off a road win. 12-6 UNDER after a win by 17 or more points. 4-0 UNDER versus poor defensive teams - allowing 425 yards/game or more.

Key Injuries


Oregon State Beavers:  T. Crandall (CB) Questionable - Foot. J. Strand (OG) Questionable - Undisclosed. N. Thomas Jr. (CB) Questionable - Undisclosed. J. Bowers (TE) Questionable - Undisclosed. T. Voltin (OG) Questionable - Knee. T. Pome'e (DL) Questionable - Undisclosed. D. Clemons (WR) Out - Achilles.

Oregon Ducks:  J. Ressler (WR) Questionable - Undisclosed. D. Gresham (WR) Questionable - Undisclosed. B. Boulton (OG) Questionable - Undisclosed. D. Brew (CB) Questionable - Undisclosed. B. Platt (LB) Questionable - Undisclosed. D. Williams (LB) Questionable - Undisclosed. N. Whittington (RB) Questionable - Undisclosed. S. Laulea (CB) Questionable - Undisclosed. A. Novosad (QB) Questionable - Undisclosed. E. Stewart (WR) Out - Knee. T. McNutt (CB) Out - Leg.

Notable Quotes


“The disappointing thing was, I thought we didn’t play with much effort or willingness to be physical. That’s my fault. I’ve allowed it to happen. Got to get it fixed.” - Trent Bray after his team’s loss against TTU in their last game. 


“When we don’t beat ourselves, we have a great chance for success. We operated clean.” - Dan Lanning after his team’s win against Northwestern in their last game. 


Starting Lineups


Oregon State Beavers
WR Wells Jr., David
WR Reddicks, Taz
WR Walker, Trent
TE Caufield, Bryce
QB Murphy, Maalik
RB Hankerson, Anthony

Oregon Ducks
WR Benson, Malik
WR Moore, Dakorien
WR Bryant Jr., Gary
TE Sadiq, Kenyon
QB Moore, Dante
RB Whittington, Noah

Statistical Leaders


Oregon State Beavers
Passing: M. Murphy (866)
Rushing: A. Hankerson (189)
Receiving: T. Walker (303)
Touchdowns: A. Hankerson (1)

Oregon Ducks
Passing: D. Moore (657)
Rushing: D. Hill Jr. (161)
Receiving: M. Benson (161)
Touchdowns: J. Davison (5)

Coaches:
Oregon State Beavers: Trent Bray (2nd season)
Oregon Ducks: Dan Lanning (4th season)


Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

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