by Rod Pearson
Wednesday, Oct 22, 2025
Game Time: 4:00 pm ET, Saturday, October 25, 2025
Venue: Jones AT&T Stadium, Lubbock, TX
Where to Watch: ESPNU
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: OK State +38.5, TTU -38.5; Over/Under: 56.5 points
Bet365: Point Spread: OK State +38, TTU -38; Over/Under: 56.5 points
BetMGM: Point Spread: OK State +38.5, TTU -38.5; Over/Under: 56.5 points
Season Record
Oklahoma State Cowboys: 1-6 (0-4) (16th place, Big 12)
Texas Tech Red Raiders: 6-1 (3-1) (3rd place, Big 12)
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Recent Form
Oklahoma State Cowboys: lost their last game at home against the Cincinnati Bearcats 49-17.
Texas Tech Red Raiders: lost their last game on the road against the Arizona State Sun Devils 26-22.
Oklahoma State Cowboys vs Texas Tech Red Raiders Preview and Analysis
Oklahoma State is entering this game with a 1-6 record overall and they have a 0-4 record in their conference games too. They are 1-4 in their home games, 0-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against Cincinnati 49-17. Sam Jackson V was the starting QB and he completed 11/19 passes for 149 passing yards, 0 touchdowns, and 1 interception. Rodney Fields Jr. led the team in rushing yards with 163 and 1 TD. Shamar Rigby led the receivers with 48 receiving yards on 1 reception. Parker Robertson led the defense in that game with 5 solo tackles and 1 assisted tackle while DeSean Brown led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.
Texas Tech is entering this game with a 6-1 record overall and they have a 3-1 record in their conference games too. They are 4-0 in their home games, 2-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against Arizona State 26-22. Will Hammond was the starting QB and he completed 22/37 passes for 167 passing yards, 2 touchdowns, and 1 interception. Will Hammond led the team in rushing yards with 47 and 1 TD. Coy Eakin led the receivers with 66 receiving yards on 5 receptions and 1 TD. Jacob Rodriguez led the defense in that game with 7 solo tackles and 5 assisted tackles while David Bailey led the defense in sacks with 2. No one on the defense came away with an interception for them in that one.
Oklahoma State vs Texas Tech Prediction
The current betting odds have Texas Tech listed as a 38.5 point favorite in this game according to Draftkings Sportsbook. Texas Tech has looked really good in their games this season with their 6-1 record overall and their 3-1 conference record which has them right near the top of the Big 12. They are ranked inside the top 25 at the moment as they have looked like one of the best teams in the nation all year, and they have looked great on their own field with their 4-0 home record this season. They have been rolling over opponents all season, but they are off their first loss of the season now. They lost on the road to Arizona State 26-22, but they were missing their starting QB in that one too. They will be looking to bounce back at home and take their frustrations out on one of the worst teams in the conference. Meanwhile, Oklahoma State has looked terrible in their games this season with their 1-6 record overall and their 0-4 conference record which has them right at the bottom of the Big 12. They are also 0-2 in their road games this year and they are off a 49-17 loss at home to Cincinnati in their last one. Their offense hasn't looked good at all this season as they can barely score 20 points in their games and their defense has looked terrible with multiple games this season where they have given up over 40 points. They aren't going to keep this angry Texas Tech team off the board and they have been getting blown out in most of their games this season too. This is a great game for Texas Tech to bounce back at home against the worst team in the Big 12. The best way to place a bet here is on Texas Tech to cover the spread in this game.
Oklahoma State Texas Tech Prediction: Our NCAAF Pick for Saturday, October 25, 2025 (4:00 pm ET start time) is Texas Tech 56 OK State 13.
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NCAAF Betting Trends
Oklahoma State Cowboys: 12-21 ATS in all lined games. 2-7 ATS as a road underdog. 3-8 ATS after a loss by 17 or more points. 13-5 OVER as an underdog. 8-2 OVER when the total is between 56.5 and 63. 15-8 OVER against conference opponents.
Texas Tech Red Raiders: 10-3 ATS as a home favorite. 10-4 ATS when the total is between 56.5 and 63. 6-1 ATS off a loss against a conference rival. 10-4 OVER as a home favorite. 8-3 OVER in a home game where the total is between 56.5 and 63. 4-1 OVER off an upset loss as a favorite.
Key Injuries
Oklahoma State Cowboys: D. Thomas (LB) Questionable - Undisclosed. D. Smith (S) Questionable - Undisclosed. K. Smith (CB) Questionable - Undisclosed. M. Samuel (OG) Questionable - Undisclosed. M. Lopez (WR) Questionable - Undisclosed. D. Lofton (WR) Questionable - Undisclosed. D. Kabongo (S) Questionable - Undisclosed. J. Johnson (DL) Questionable - Undisclosed. H. Hejny (QB) Questionable - Foot. O. Hammond (TE) Questionable - Undisclosed. S. Freibaum (LS) Questionable - Undisclosed. J. Ford (TE) Questionable - Undisclosed. J. Davies (CB) Questionable - Undisclosed. L. Canepa (OG) Questionable - Undisclosed. D. Boykins (S) Questionable - Undisclosed. J. Johnson (CB) Questionable - Undisclosed. Z. Flores (QB) Questionable - Undisclosed. T. Shettron (WR) Out - Knee.
Texas Tech Red Raiders: D. Carter (OG) Questionable - Foot. C. Lewis (S) Questionable - Undisclosed. T. West (WR) Questionable - Undisclosed. T. Grant (CB) Questionable - Undisclosed. S. Gill-Howard (DL) Out - Leg. D. Singleton (DL) Out - Undisclosed. Q. Joyner (RB) Out - Knee. M. Dingle Jr. (S) Out - Leg.
Notable Quotes
“Just some little minor miscues that turned catastrophic, you know what I mean. It’s like a little bitty thing that just completely implodes on us.” - Doug Meacham after his team’s loss against Cincinnati in their last game.
“That quarterback changes everything. He's a difference maker.” - Joey McGuire after his team’s loss against ASU in their last game.
Starting Lineups
Oklahoma State Cowboys
WR Davis, Terrill
WR Rigby, Shamar
WR Freeman, Gavin
TE Stewart, Quinton
QB Flores, Zane
RB Fields Jr., Rodney
Texas Tech Red Raiders
WR Virgil, Reggie
WR Douglas, Caleb
WR Eakin, Coy
TE Miller II, Johncarlos
QB Morton, Behren
RB Dickey, Cameron
Statistical Leaders
Oklahoma State Cowboys
Passing: Zane Flores (696)
Rushing: Rodney Fields Jr. (420)
Receiving: Gavin Freeman (233)
Touchdowns: Trent Howland (2)
Texas Tech Red Raiders
Passing: Behren Morton (1,501)
Rushing: Cameron Dickey (631)
Receiving: Caleb Douglas (414)
Touchdowns: Cameron Dickey (9)
Coaches:
Oklahoma State Cowboys: Doug Meacham (Interim)
Texas Tech Red Raiders: Joey McGuire (4th season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
