Oklahoma City Thunder vs San Antonio Spurs Prediction, Preview and Odds - 05/22/2026

by Rod Pearson

Thursday, May 21, 2026
Game Time: 8:30 pm ET, Friday, May 22, 2026
Venue:  Paycom Center, Oklahoma City, OK 
Where to Watch:  NBC, Peacock


Opening Odds at USA Sportsbooks

DraftKings:  Point Spread:  Thunder +2.5, Spurs -2.5; Over/Under:  216.5 points
Bet365:  Point Spread:  Thunder +2.5, Spurs -2.5; Over/Under:  216.5 points
BetMGM:  Point Spread:  Thunder +2.5, Spurs -2.5; Over/Under:  216.5 points

Season Record

Oklahoma City Thunder:  64-18 (1st place, Northwest Division)
San Antonio Spurs:  62-20 (1st place, Southwest Division)

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Recent Form
Oklahoma City Thunder:  9-1 last 10
San Antonio Spurs:  7-3 last 10


Oklahoma City Thunder vs San Antonio Spurs Preview and Analysis


The Thunder are entering the playoffs with a 64-18 record overall this season and they were 30-10 in their road games where they will be in this game. They are entering this game off a win against the San Antonio Spurs. Shai Gilgeous-Alexander led the team in points in that game with 30 while Alex Caruso was next on the team with 17 points. Shai Gilgeous-Alexander led the team in assists in that game with 9 while Isaiah Hartenstein led the team in rebounds with 13. They were 47.9% from the field, 36.1% from 3-point range, and 79.2% from the free throw line with their shots in that game. Their offense is averaging 119 PPG and their defense is allowing their opponents to average 107.9 PPG against them. The Thunder have an ATS record of 45-47 this season and their O/U record is 51-41.



The Spurs are entering the playoffs with a 62-20 record overall this season and they were 32-8 in their home games where they will be in this game. They are entering this game off a loss against the Oklahoma City Thunder. Stephon Castle led the team in points in that game with 25 while Devin Vassell was next on the team with 22 points. Stephon Castle led the team in assists in that game with 8 while Victor Wembanyama led the team in rebounds with 17. They were 48.8% from the field, 40% from 3-point range, and 88.2% from the free throw line with their shots in that game. Their offense is averaging 119.8 PPG and their defense is allowing their opponents to average 111.5 PPG against them. The Spurs have an ATS record of 55-39-2 this season and their O/U record is 45-51.


Thunder vs Spurs Prediction

The current betting odds have the Spurs listed as a 2.5 point favorite in this game according to Draftkings Sportsbook. The Spurs have looked great in their games this season with their 60-22 record overall which had them right near the top of the West with one of the best records in the entire NBA. They have looked great on their home court too with their 32-8 home record this season. Meanwhile, the Thunder have looked great in their games this season with their 64-18 record overall which had them right at the top of the West with the best record in the entire NBA. They have been a great road team too with their 30-10 road record this year. This is game 3 of a 7-game series between the 1st seeded Thunder and the 2nd seeded Spurs for the Western Conference Finals of the NBA playoffs. This series is all evened up 1-1 after the Thunder won game 2 by a score of 122-113. The Thunder lost the 1st game of this series at home and it was a game that they were trailing in for most of the time. They have had a lot of trouble with the Spurs this season, but they answered back with a much better effort in game 2 and pretty much led the entire way. Now they are going on the road for game 3 with the series tied, but they have the pressure on themselves to flip the home advantage in this series back in their favor. The Thunder were undefeated in the playoffs entering this series, but they haven't really been challenged by a team like the Spurs who were consistently one of the best teams in the NBA all year. Fox has also been missing from the lineup for the Spurs, but they should be getting him back soon and that will be a big boost to the lineup. The Thunder had a good answer in game 2, but they still had a lot of trouble keeping their lead when they would go on runs to get ahead by double digits and the Spurs have had their number all season. Look for the Spurs to answer back at home after that loss as this is not going to be a one-sided series. The best way to place a bet here is on the Spurs to cover the spread in this game. 

Thunder Spurs Prediction:  Our NBA Pick for Friday, May 22, 2026 (8:30 pm ET start time) is Spurs 121 Thunder 115.
Don't miss our champion handicappers free picks and expert basketball picks today.  And if you enjoyed this Oklahoma City Thunder San Antonio Spurs prediction, be sure to drop by every day for our weekly NBA predictions and previews.

NBA Betting Trends


Oklahoma City Thunder: 19-29 ATS versus good 3 point shooting teams - making 36% of their attempts or more. 6-11 ATS versus good rebounding teams - outrebounding opponents by 3+ per game. 8-16 ATS versus good teams - outscoring their opponents by 3+ points/game. 7-1 OVER in a road game where the total is 210 to 219.5. 27-16 OVER versus good offensive teams - scoring 116+ points/game.

San Antonio Spurs: 11-6 ATS as a home favorite of 6 points or less. 10-5 ATS when playing against a top-level team (Win Pct. > 70%). 9-4 ATS in all playoff games. 10-5 OVER after 3 or more consecutive overs. 7-3 OVER when the total is 210 to 219.5.

Key Injuries


Oklahoma City Thunder:  J. Williams (SF) Day To Day - Hamstring. T. Sorber (C) Out For Season - Knee.

San Antonio Spurs:  D. Harper (SG) Day To Day - Leg. D. Fox (PG) Day To Day - Ankle. D. Jones Garcia (SF) Out For Season - Ankle.


Notable Quotes


“I thought we all played better. I had a quiet confidence about that. I didn't know if we'd win or lose the game, but I was pretty sure after watching Game 1 and knowing our team that we were going to come out and play better tonight.” - Mark Daigneault after his team’s win against the Spurs in the 2nd game of this series on Wednesday. 


“Obviously this team is as good as anybody at turning you over, so when you’re down some of your primary creators and initiators it causes a little bit of an extra strain, whether that’s who to play, what to play, what to run, etc., etc. We’ll just have to be sharper in that area because it’s tough fully loaded against these guys.” - Mitch Johnson after his team’s loss against the OKC Thunder in game 2 of this series on Wednesday. 


Starting Lineups


Oklahoma City Thunder
PG Shai Gilgeous-Alexander
SG Luguentz Dort
SF Jalen Williams
PF Chet Holmgren
C Isaiah Hartenstein

San Antonio Spurs
PG De'Aaron Fox
SG Stephon Castle
SF Devin Vassell
PF Julian Champagnie
C Victor Wembanyama

Statistical Leaders


Oklahoma City Thunder
PPG: Shai Gilgeous-Alexander (31.1)
APG: Shai Gilgeous-Alexander (6.6)
Reb/G: Isaiah Hartenstein (9.4)

San Antonio Spurs
PPG: Victor Wembanyama (25)
APG: Stephon Castle (7.4)
Reb/G: Victor Wembanyama (11.5)

Coaches:
Oklahoma City Thunder: Mark Daigneault (6th season)
San Antonio Spurs: Mitch Johnson (2nd season)



Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

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