by Rod Pearson
Wednesday, Oct 15, 2025
Game Time: 3:30 pm ET, Saturday, October 18, 2025
Venue: Camp Randall Stadium, Madison, WI
Where to Watch: CBS
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Ohio State -25.5, Wisconsin +25.5; Over/Under: 40.5 points
Bet365: Point Spread: Ohio State -26, Wisconsin +26; Over/Under: 41 points
BetMGM: Point Spread: Ohio State -25.5, Wisconsin +25.5; Over/Under: 41.5 points
Season Record
Ohio State Buckeyes: 6-0 (3-0) (2nd place, Big Ten)
Wisconsin Badgers: 2-4 (0-3) (18th place, Big Ten)
Do not miss out on our expert handicapper analysis! Brian Bitler is on a HOT STREAK in college football on a 22-11-2 CFB RUN for +$10,000 PROFIT! Make sure you check out his picks and many more from the expert handicappers featured in the Shop Picks section.
Recent Form
Ohio State Buckeyes: won their last game on the road against the Illinois Fighting Illini 34-16.
Wisconsin Badgers: lost their last game at home against the Iowa Hawkeyes 37-0.
Ohio State Buckeyes vs Wisconsin Badgers Preview and Analysis
Ohio State is entering this game with a 6-0 record overall and they have a 3-0 record in their conference games too. They are 4-0 in their home games, 2-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against Illinois 34-16. Julian Sayin was the starting QB and he completed 19/27 passes for 166 passing yards, 2 touchdowns, and 0 interceptions. Bo Jackson led the team in rushing yards with 47. Jeremiah Smith led the receivers with 42 receiving yards on 5 receptions and 1 TD. Sonny Styles led the defense in that game with 8 solo tackles and 2 assisted tackles while Arvell Reese led the defense in sacks with 1.5. Payton Pierce came away with the only interception for them in that one.
Wisconsin is entering this game with a 2-4 record overall and they have a 0-3 record in their conference games too. They are 2-2 in their home games, 0-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against Iowa 37-0. Hunter Simmons was the starting QB and he completed 8/21 passes for 82 passing yards, 0 touchdowns, and 2 interceptions. Dilin Jones led the team in rushing yards with 69. Lance Mason led the receivers with 29 receiving yards on 1 reception. Christian Alliegro led the defense in that game with 8 solo tackles and 2 assisted tackles while no one on the defense recorded a sack for them. Ricardo Hallman came away with the only interception for them in that one.
Ohio State vs Wisconsin Prediction
The current betting odds have Ohio State listed as a 25.5 point favorite in this game according to Draftkings Sportsbook. Ohio State has looked great in their games this season with their 6-0 record overall and their 3-0 conference record which has them right near the top of the Big Ten. They are off a 34-16 road win over Illinois in their last one and they are ranked number 1 in the nation. They have one of the best defenses in the nation that has been crippling opposing offenses all season, and their offense has also looked great even though they look like they have been holding back. Meanwhile, Wisconsin has looked terrible in their games this season with their 2-4 record overall and their 0-3 conference record which has them right near the bottom of the Big Ten. They are off a 37-0 home loss to Iowa in their last one and they are starting to look like one of the worst teams in the conference. Wisconsin is a disaster this season as the Luke Fickell hire just hasn't worked out for them. Their offense has looked terrible as they have no identity under Fickell, and they don't even have a good defense to keep them in games either. Ohio State has been rolling over teams all season and there is no reason to believe that Wisconsin can put up a good fight in this game against the best team in the country. The best way to place a bet here is on Ohio State to cover the spread in this game.
Ohio State Wisconsin Prediction: Our NCAAF Pick for Saturday, October 18, 2025 (3:30 pm ET start time) is Ohio State 42 Wisconsin 3.
Don't miss our champion handicappers free picks and expert football picks today. And if you enjoyed this Ohio State Buckeyes Wisconsin Badgers prediction, be sure to drop by every day for our weekly NCAAF predictions and previews.
NCAAF Betting Trends
Ohio State Buckeyes: 22-11 ATS in all lined games. 22-10 ATS as a favorite. 12-6 ATS off a win against a conference rival. 22-13 UNDER in all lined games. 8-2 UNDER as a road favorite. 13-5 UNDER off a win against a conference rival.
Wisconsin Badgers: 5-12 ATS in home lined games. 3-7 ATS after scoring 14 points or less last game. 3-6 ATS vs. good defensive teams who give up 17 or less points/game. 13-5 UNDER in home lined games. 7-2 UNDER vs. good defensive teams who give up 17 or less points/game.
Key Injuries
Ohio State Buckeyes: M. Roy (DL) Questionable - Undisclosed. T. Rogers (RB) Questionable - Undisclosed. D. Stewart (S) Questionable - Undisclosed. A. Tounkara (DL) Questionable - Undisclosed. M. LeBlanc (TE) Questionable - Undisclosed. E. Mensah (DL) Questionable - Undisclosed. E. Houston (DL) Questionable - Undisclosed. B. Rodgers (WR) Questionable - Undisclosed. M. Maggs (QB) Questionable - Undisclosed. L. Styles Jr. (CB) Questionable - Undisclosed.
Wisconsin Badgers: J. Griffin Jr. (WR) Questionable - Undisclosed. D. Hill (CB) Questionable - Undisclosed. P. Zachman (S) Questionable - Undisclosed. L. Nelson (OG) Questionable - Undisclosed. T. Pettaway (DL) Questionable - Undisclosed. B. Edwards Jr. (QB) Questionable - Knee. K. Heywood (OG) Questionable - Undisclosed. E. Van Dyn Hoven (LB) Questionable - Undisclosed. E. Bork (TE) Questionable - Undisclosed. B. Nelson (OG) Questionable - Undisclosed. D. Crowdus (WR) Questionable - Undisclosed. B. Lemirand (WR) Out - Undisclosed.
Notable Quotes
“They're competitive. They're edgy. They like these types of environments. They want to be great and expect to be great. They expect to win all the time.” - Ryan Day after his team’s win against Illinois in their last game.
“Well, that’s as low as it can be. I apologize. I apologize to our guys to not be ready, to not have them ready. I’m dumbfounded in a lot of ways. But, that’s my job.” - Luke Fickell after his team’s loss against Iowa in their last game.
Starting Lineups
Ohio State Buckeyes
WR Tate, Carnell
WR Smith, Jeremiah
WR Inniss, Brandon
TE Kacmarek, Will
QB Sayin, Julian
RB Donaldson, CJ
Wisconsin Badgers
WR Anthony II, Vinny
WR Brooks Jr., Chris
WR Kekahuna, Trech
TE Mason, Lance
QB Simmons, Hunter
RB Jones, Dilin
Statistical Leaders
Ohio State Buckeyes
Passing: Julian Sayin (1,479)
Rushing: Bo Jackson (407)
Receiving: Jeremiah Smith (505)
Touchdowns: Jeremiah Smith (8)
Wisconsin Badgers
Passing: Danny O'Neil (640)
Rushing: Dilin Jones (286)
Receiving: Vinny Anthony II (274)
Touchdowns: Lance Mason (2)
Coaches:
Ohio State Buckeyes: Ryan Day (8th season)
Wisconsin Badgers: Luke Fickell (4th season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
