Game Time: 3:30 pm ET, Saturday, September 27, 2025
Venue: Husky Stadium, Seattle, WA
Where to Watch: CBS, Paramount+
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Ohio State -7.5, Washington +7.5; Over/Under: 51.5 points
Bet365: Point Spread: Ohio State -8.5, Washington +8.5; Over/Under: 52 points
BetMGM: Point Spread: Ohio State -8.5, Washington +8.5; Over/Under: 51.5 points
Season Record
Ohio State Buckeyes: 3-0 (0-0) (9th place, Big Ten)
Washington Huskies: 3-0 (0-0) (7th place, Big Ten)
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Ohio State Buckeyes: won their last game at home against the Ohio Bobcats 37-9.
Washington Huskies: won their last game on the road against the Washington State Cougars 59-24.
Ohio State Buckeyes vs Washington Huskies Preview and Analysis
Ohio State is entering this game with a 3-0 record overall and they have a 0-0 record in their conference games too. They are 3-0 in their home games, 0-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against Ohio 37-9. Julian Sayin was the starting QB and he completed 25/32 passes for 347 passing yards, 3 touchdowns, and 2 interceptions. Bo Jackson led the team in rushing yards with 109. Jeremiah Smith led the receivers with 153 receiving yards on 9 receptions and 1 TD. Jaylen McClain led the defense in that game with 4 solo tackles and 1 assisted tackle while Kayden McDonald, Beau Atkinson, Caden Curry, and Arvell Reese each led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.
Washington is entering this game with a 3-0 record overall and they have a 0-0 record in their conference games too. They are 2-0 in their home games, 1-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against Washington State 59-24. Demond Williams Jr. was the starting QB and he completed 16/19 passes for 298 passing yards, 4 touchdowns, and 0 interceptions. Demond Williams Jr. led the team in rushing yards with 88 and 1 TD. Denzel Boston led the receivers with 107 receiving yards on 6 receptions and 2 TDs. Leroy Bryant led the defense in that game with 4 solo tackles and 1 assisted tackle while Armon Parker led the defense in sacks with 1. Alex McLaughlin came away with the only 2 interceptions for them in that one.
Ohio State vs Washington Prediction
The current betting odds have Ohio State listed as a 7.5 point favorite in this game according to Draftkings Sportsbook. Ohio State has looked great in their games this season with their 3-0 record overall. They opened the season with a big home win over Texas and haven't really played anyone of note since that game. This is going to be their first road game and their first conference game of the season now, but they are also off a bye week so they are going to be prepared for this game, and they are still the defending National champions. Their offense has looked a lot better since that first game against Texas and their defense has shown that they could be just as good as last season, if not better. Meanwhile, Washington has looked great in their games this season with their 3-0 record overall. They are off a 59-24 win over Wazzu in their last one and their offense has been rolling in their games this season. Their defense has been giving up some points to much weaker teams though and that could be a big issue in this game. Washington does have the luxury of being at home here, but this is still their first conference game of the year against what might be the best team in the Big Ten and they haven't really been tested in their 3 games so far. Their defense is going to struggle a lot more here against the best offense they will see up to this point, and they definitely haven't seen a defense like this either. The best way to place a bet here is on Ohio State to cover the spread in this game.
Ohio State Washington Prediction: Our NCAAF Pick for Saturday, September 27, 2025 (3:30 pm ET start time) is Ohio State 34 Washington 20.
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NCAAF Betting Trends
Ohio State Buckeyes: 19-10 ATS as a favorite. 13-6 ATS after allowing 14 points or less last game. 8-4 ATS after scoring 37 points or more last game. 20-11 UNDER as a favorite. 14-5 UNDER against conference opponents.
Washington Huskies: 0-4 ATS after a game with a turnover margin of +2 or better. 4-8 ATS vs. good passing teams averaging 8 or more passing yards/att. 2-7 ATS vs. good defensive teams who give up 17 or less points/game. 7-3 UNDER as an underdog. 6-3 UNDER after a win by 17 or more points.
Key Injuries
Ohio State Buckeyes: A. Rogers (RB) Questionable - Undisclosed. M. Roy (DL) Questionable - Undisclosed. D. Stewart (S) Questionable - Undisclosed. A. Tounkara (DL) Questionable - Undisclosed. M. LeBlanc (TE) Questionable - Undisclosed. J. Moore (DL) Questionable - Undisclosed. M. Maggs (QB) Questionable - Undisclosed. I. Jones (S) Questionable - Undisclosed. B. Christian (TE) Questionable - Undisclosed.
Washington Huskies: R. Wright II (S) Questionable - Undisclosed. R. Williams (WR) Questionable - Collarbone. Z. Rainey-Sale (LB) Questionable - Undisclosed. J. Parker (DL) Questionable - Undisclosed. D. McCutcheon (S) Questionable - Undisclosed. J. Manu (LB) Questionable - Undisclosed. R. Davis II (DL) Questionable - Undisclosed. T. Davis (CB) Questionable - Undisclosed. C. Crowell (TE) Questionable - Undisclosed. C. Christian (S) Questionable - Undisclosed.
Notable Quotes
“Demond is sensational. I think a lot of the country saw what Demond can do today, being a national game… and we’ll see what it looks like in the future. But he’s super special, and I can’t wait to see him keep getting better.” - Jedd Fisch after his team’s win against WSU in their last game.
“We know this is gonna be a great challenge, being on the road, a very good team. For these guys, this group, it will be our first time on the road. Whatever we’ve done in the first three games means absolutely nothing going into this game. We’ve got to go on the road and get this win.” - Ryan Day on his team’s upcoming game against Washington this week.
Starting Lineups
Ohio State Buckeyes
WR Tate, Carnell
WR Smith, Jeremiah
WR Inniss, Brandon
TE Kacmarek, Will
QB Sayin, Julian
RB Donaldson, CJ
Washington Huskies
WR Boston, Denzel
WR Evans, Omari
WR Williams, Rashid
TE Moore, Quentin
QB Williams Jr., Demond
RB Coleman, Jonah
Statistical Leaders
Ohio State Buckeyes
Passing: Julian Sayin (779)
Rushing: Bo Jackson (217)
Receiving: Jeremiah Smith (315)
Touchdowns: Jeremiah Smith (4)
Washington Huskies
Passing: Demond Williams Jr. (778)
Rushing: Jonah Coleman (347)
Receiving: Denzel Boston (249)
Touchdowns: Jonah Coleman (10)
Coaches:
Ohio State Buckeyes: Ryan Day (8th season)
Washington Huskies: Jedd Fisch (2nd season)