Ohio Bobcats vs Ohio State Buckeyes Prediction, Picks and Game Preview - 09/13/2025

Game Time: 7:00 pm ET, Saturday, September 13, 2025

Venue:  Ohio Stadium, Columbus, OH

Where to Watch:  Peacock

DraftKings:  Point Spread:  Ohio +31.5, OSU -31.5; Over/Under:  51.5 points

Bet365:  Point Spread:  Ohio +31, OSU -31; Over/Under:  52 points

BetMGM:  Point Spread:  Ohio +31.5, OSU -31.5; Over/Under:  52.5 points

Ohio Bobcats:  1-1 (0-0) (3rd place, MAC)

Ohio State Buckeyes:  2-0 (0-0) (7th place, Big Ten)

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Ohio Bobcats:  won their last game at home against the West Virginia Mountaineers 17-10.

Ohio State Buckeyes:  won their last game at home against the Grambling State Tigers 70-0.

Ohio is entering this game with a 1-1 record overall and they have a 0-0 record in their conference games too. They are 1-0 in their home games, 0-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against West Virginia 17-10. Parker Navarro was the starting QB and he completed 22/31 passes for 247 passing yards, 1 touchdown, and 3 interceptions. Parker Navarro led the team in rushing yards with 87. Chase Hendricks led the receivers with 121 receiving yards on 8 receptions and 1 TD. DJ Walker led the defense in that game with 5 solo tackles and 2 assisted tackles while Michael Molnar led the defense in sacks with 1.5. Cameron Hollobaugh came away with the only interception for them in that one.

 

 

 

Ohio State is entering this game with a 2-0 record overall and they have a 0-0 record in their conference games too. They are 2-0 in their home games, 0-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against Grambling State 70-0. Julian Sayin was the starting QB and he completed 18/19 passes for 306 passing yards, 4 touchdowns, and 1 interception. Bo Jackson led the team in rushing yards with 108 and 1 TD. Jeremiah Smith led the receivers with 119 receiving yards on 5 receptions and 2 TDs. Caden Curry and Jaylen McClain each led the defense in that game with 4 solo tackles and 0 assisted tackles while Caden Curry and Zion Grady each led the defense in sacks with 1. Caleb Downs came away with the only interception for them in that one.

The current betting odds have Ohio State listed as a 31.5 point favorite in this game according to Draftkings Sportsbook. Ohio State has a 2-0 record overall this season and they have looked great in their 2 games so far. They just beat up on a team from the FCS, beating Grambling State 70-0, and they have a really good win at home over Texas in their season opener. They are ranked 1st overall in the nation and even though their offense didn't look great against Texas, it looked a lot better last week and Ohio doesn't have the talent on defense that Texas has. Meanwhile, Ohio has a 1-1 record overall this season and they have looked good in their 2 games. They lost their season opener to Rutgers by 3 points, but they almost pulled off a comeback win in that one. Now they are off a 17-10 win at home over West Virginia in their last one. As good as Ohio has looked in 2 games against power 4 schools, they still haven't seen the talent that this Ohio State team has and they still have a head coach in his 1st year there. Ohio's defense will only be able to hold off this Ohio State offense for so long before the flood gates open to the talent they have on that team. Ohio State also has one of the best defenses in the nation again so it isn't going to be nearly as easy for this Ohio offense to move the ball in this road game, especially when they could only put up 17 points at home in their win against WVU last week. The best way to place a bet here is on Ohio State to cover the spread in this game. 

Ohio Ohio State Prediction:  Our NCAAF Pick for Saturday, September 13, 2025 (7:00 pm ET start time) is Ohio State 49 Ohio 13.

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Ohio Bobcats: 18-24 ATS on the road after allowing 14 points or less last game. 6-10 1H ATS against Big 10 conference opponents. 17-25 1H ATS in a road game where the total is between 49.5 and 56. 7-3 UNDER in non-conference games. 

Ohio State Buckeyes: 19-10 ATS as a favorite. 12-5 ATS in home lined games. 8-4 ATS after scoring 37 points or more last game. 13-6 ATS after allowing 14 points or less last game. 19-11 UNDER as a favorite. 9-4 UNDER after scoring 37 points or more last game.

Ohio Bobcats:  T. Mathis (CB) Questionable - Undisclosed. R. Keuchler (DL) Questionable - Undisclosed. K. Hurst (WR) Questionable - Undisclosed. K. Seegars (DL) Questionable - Undisclosed. J. Winters (QB) Questionable - Undisclosed. A. Kasee (K) Questionable - Undisclosed. B. Miller (CB) Questionable - Undisclosed.

Ohio State Buckeyes:  M. LeBlanc (TE) Questionable - Undisclosed. A. Rogers (RB) Questionable - Undisclosed. M. Maggs (QB) Questionable - Undisclosed. J. Moore (DL) Questionable - Undisclosed. M. Roy (DL) Questionable - Undisclosed. A. Tounkara (DL) Questionable - Undisclosed. D. Stewart (S) Questionable - Undisclosed. I. Jones (S) Questionable - Undisclosed.

“Our kids are extremely competitive. They're very confident. They obviously know that this is a big challenge, and we're playing a really strong program that has obviously earned that right to be one of the top programs in the country, and they're excited for the challenge. I think having confidence going into a situation like that is very important. It's important that your players and your staff believe in each other, trust each other, and believe and trust in their abilities as kids and as a staff.” - Brian Smith on his team’s upcoming game against Ohio State this week.

“We talked about being more explosive and playing with tempo. That was good. I thought Julian really had some accurate throws, the ball came out on time and the spacing, timing and protection was good. You know they (Grambling) were outmatched talent-wise for sure, and I think (coach Mickey Joseph) expressed that. But I give them a lot of respect for playing hard and playing for four quarters all the way to the end.” - Ryan Day after his team’s win against Grambling State in their last game. 

WR Harris II, Rodney

WR Hendricks, Chase

WR Rodarte, Max

TE Williams, Mason

QB Navarro, Parker

RB Bangura, Sieh

WR Tate, Carnell

WR Smith, Jeremiah

WR Inniss, Brandon

TE Kacmarek, Will

QB Sayin, Julian

RB Donaldson, CJ

Passing: P. Navarro (486)

Rushing: P. Navarro (180)

Receiving: C. Hendricks (236)

Touchdowns: J. Bruno (2)

Passing: J. Sayin (432)

Rushing: C. Donaldson (112)

Receiving: J. Smith (162)

Touchdowns: J. Smith (2)

Coaches:

Ohio Bobcats: Brian Smith (1st season)

Ohio State Buckeyes: Ryan Day (8th season)