New York Yankees vs Philadelphia Phillies Prediction, Preview and Odds - 07/25/2026

Game Time: 6:05 pm ET, Saturday, July 25, 2026

Venue:  Citizens Bank Park, Philadelphia, PA 

Where to Watch:  MLB TV

DraftKings:  Moneyline odds:  Yankees -118, Phillies -102; Over/Under:  8.5 runs

Bet365:  Moneyline odds:  Yankees -115, Phillies -105; Over/Under:  8.5 runs

BetMGM:  Moneyline odds:  Yankees -115, Phillies +100; Over/Under:  8.5 runs

New York Yankees:  57-45 (2nd place, AL East)

Philadelphia Phillies:  56-47 (2nd place, NL East)

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New York Yankees:  7-3 last 10

Philadelphia Phillies:  5-5 last 10

The Yankees are entering this series off a win and won their 3-game series against the Pittsburgh Pirates 2-1 in their last series. They enter this game with a 57-45 record overall and have a road record of 31-22. This is the 2nd game of a 3-game series with the Phillies on Saturday with the series opener still to be played on Friday. Their offense ranks 7th in the MLB with a .735 OPS. Cam Schlittler is their starting pitcher on Friday while Ryan Weathers is making his start in this game on Saturday. He is 3-7 with a 4.40 ERA this season. His team won their last 2 straight games this season with him making an appearance. In his last MLB regular season appearance, he allowed 5 ER, 1 HR, and 2 BB with 5 SO on 7 hits through 4.2 IP against the Pittsburgh Pirates.

The Phillies are entering this series off a loss and lost their 3-game series against the Los Angeles Dodgers 2-1 in their last series. They enter this game with a 56-47 record overall and have a home record of 27-25. This is the 2nd game of a 3-game series with the Yankees on Saturday with the 1st game of this series still to be played on Friday. Their offense ranks 23rd in the MLB with a .705 OPS. Jesús Luzardo is their starting pitcher on Friday while Brad Keller is making his start in this game on Saturday. He is 2-1 with a 4.02 ERA this season. His team won 11 of their last 12 games this season with him making an appearance. In his last MLB regular season appearance, he allowed 0 earned runs, 0 homers, and 1 walk with 1 strikeout on 0 hits through 1 inning pitched against the Cincinnati Reds.

The current betting odds have the Yankees listed as a slight favorite in this game according to Draftkings Sportsbook. The Phillies have looked good in their games this season with their 56-47 record overall which has them right near the top of the NL East. They have looked good in their own ballpark too with their 27-25 home record this season. Meanwhile, the Yankees have looked good in their games this season with their 57-45 record overall which has them right near the top of the AL East. They have been a good road team too with their 31-22 road record this year. The Phillies are 5-5 in their last 10 games and they haven't looked great lately. Their pitching has been really good over the last few weeks, but lately they have been slipping up with their bullpen underperforming and they aren't going to have a solid option starting in this one either. The Yankees also have a really good pitching staff that has been good lately and they have been rolling, now 7-3 in their last 10 games. The Yankees are going with Weathers in this one and he hasn't looked great this season. He is 3-7 with a 4.40 ERA, but lately the team has been having more success with him. They have won 2 games in a row now with him starting and even though he gave up 5 earned runs in his last start, he will be looking to bounce back with a better performance. The Yankees don't have the best option starting in this game either, but their bullpen has been great all year and they still have the stronger offense to bail Weathers out too. The best way to place a bet here is on the Yankees to win this game. 

Yankees Phillies Prediction:  Our MLB Pick for Saturday, July 25, 2026 (6:05 pm ET start time) is Yankees 7 Phillies 4.

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New York Yankees: 22-21 (-7.2 units) on the moneyline against NL East opponents. 255-191 (-19.2 units) on the moneyline in all games. 62-60 (-22.8 units) on the moneyline in an inter-league game. 31-20 UNDER in road games. 24-10 UNDER on the road when the money line is +125 to -125.

Philadelphia Phillies: 25-15 (+7.4 units) on the moneyline against AL East opponents. 250-186 (+9.5 units) on the moneyline in all games. 138-81 (+19.7 units) on the moneyline in home games. 27-11 UNDER when the money line is +125 to -125. 19-6 UNDER vs. a team with a good bullpen whose ERA is 3.45 or better.

New York Yankees:  A. Judge (RF) Sixty Day IL - Rib. C. Rodon (SP) Fifteen Day IL - Elbow. G. Stanton (DH) Ten Day IL - Leg. C. Schmidt (SP) Sixty Day IL - Elbow.

Philadelphia Phillies:  R. Marchan (C) Day To Day - Knee. G. Stubbs (C) Ten Day IL - Wrist. B. Keller (RP) Fifteen Day IL - Elbow. T. Banks (RP) Fifteen Day IL - Forearm. L. Trivino III (RP) Fifteen Day IL - Back. J. Rojas (CF) Sixty Day IL - Elbow. A. Garcia (RF) Sixty Day IL - Lat.

“He looked great, obviously. Frankly, as good as he’s looked all year, in any of his other starts. You’re kind of hoping he can get you three innings, maybe 10 outs. And to be that efficient to throw five innings shutout, I thought [he] was really sharp from the jump.” - Aaron Boone on Max Fried after his team’s win against the Pirates in game 2 of their double-header on Wednesday.

“It is something that I'm thinking about and looking at because, obviously, the numbers haven't been great against the lefties. I've liked some of the at-bats early, but that seems to have been a battle as we went on.” - Don Mattingly on Brandon Marsh against lefties after his team’s loss against the LA Dodgers on Wednesday. 

Trent Grisham (L) CF

Ben Rice (L) DH

Paul Goldschmidt (R) 1B

Cody Bellinger (L) LF

Jazz Chisholm Jr. (L) 2B

Jasson Domínguez (S) RF

Anthony Volpe (R) SS

Ryan McMahon (L) 3B

Ali Sánchez (R) C

Trea Turner (R) SS

Kyle Schwarber (L) DH

Bryce Harper (L) 1B

Alec Bohm (R) 3B

Edmundo Sosa (R) LF

Derek Hill (R) CF

Bryan De La Cruz (R) RF

Bryson Stott (L) 2B

Rafael Marchán (S) C

Batting Average:  Ben Rice (.277)

Hits:  Ben Rice (100)

Home Runs:  Ben Rice (30)

RBI:  Ben Rice (71)

Stolen Bases:  Jazz Chisholm (27)

Wins:  Cam Schlittler (9)

Saves:  David Bednar (18)

ERA:  Yovanny Cruz (0.00)

Batting Average:  Bryan De La Cruz (.500)

Hits:  Brandon Marsh (105)

Home Runs:  Kyle Schwarber (33)

RBI:  Kyle Schwarber (61)

Stolen Bases:  Trea Turner (17)

Wins:  Cristopher Sánchez (12)

Saves:  Jhoan Duran (24)

ERA:  Bryse Wilson (0.00)

Managers:

New York Yankees: Aaron Boone (9th season)

Philadelphia Phillies: Don Mattingly (Interim)