New York Mets vs Detroit Tigers Prediction, Preview and Odds - 09/03/2025

Game Time: 1:10 pm ET, Wednesday, September 3, 2025

Venue:  Comerica Park, Detroit, MI

Where to Watch:  MLBN

DraftKings:  Moneyline odds:  Mets -115, Tigers -105; Over/Under:  8.5 runs

Bet365:  Moneyline odds:  Mets -115, Tigers -105; Over/Under:  8.5 runs

BetMGM:  Moneyline odds:  Mets -115, Tigers -105; Over/Under:  8.5 runs

New York Mets:  74-64 (2nd place, NL East)

Detroit Tigers:  80-59 (1st place, AL Central)

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New York Mets:  6-4 last 10

Detroit Tigers:  4-6 last 10

The Mets are entering this series off a loss and lost their 4-game series against the Miami Marlins 3-1 in their last series. They enter this game with a 74-64 record overall and have a road record of 29-37. This is the series finale of a 3-game series with the Tigers on Wednesday with the 2nd game of this series still to be played on Tuesday. The Mets won the series opener on Monday. Their offense ranks 5th in the MLB with a .759 OPS. Rookie pitcher Nolan McLean is their starting pitcher on Tuesday while Clay Holmes is making his start in this game on Wednesday. He is 11-6 with a 3.60 ERA this season. His team won 3 of their last 4 games this season with him making an appearance. In his last MLB regular season appearance, he allowed 2 ER, 0 HR, and 1 BB with 2 SO on 5 hits through 5 IP against the Miami Marlins.

The Tigers are entering this series off a win and won their 3-game series against the Kansas City Royals 2-1 in their last series. They enter this game with an 80-59 record overall and have a home record of 44-26. This is the 3rd game of a 3-game series with the Mets on Wednesday with the 2nd game of this series still to be played on Tuesday. The Tigers lost the 1st game of this series on Monday. Their offense ranks 10th in the MLB with a .742 OPS. Sawyer Gipson-Long is their starting pitcher on Tuesday while Casey Mize is making his start in this game on Wednesday. He is 12-5 with a 3.95 ERA this season. His team won 5 of their last 6 games this season with him making an appearance. In his last MLB regular season start, he allowed 5 earned runs, 1 homer, and 2 walks with 4 strikeouts on 7 hits through 3.1 innings pitched against the Athletics.

The current betting odds have the Mets listed as a slight favorite in this game according to Draftkings Sportsbook. The Mets have looked really good in their games this season with their 74-64 record overall which has them right near the top of the NL East. They haven't been a great road team though with their 29-37 road record this year. Meanwhile, the Tigers have looked great in their games this season with their 80-59 record overall which has them right at the top of the AL Central with one of the best records in the entire MLB. They have also looked great in their own ballpark this year with their 44-26 home record. As good as they have looked all season, the Tigers haven't looked great lately as they are only 4-6 in their last 10 games while the Mets are 6-4 and have been getting hot. The Tigers are going with Mize in this one and he has looked good this season. He is 12-5 with a 3.95 ERA, but lately he has been giving up a lot more runs. His team has still had a lot of success with him, winning 5 of their last 6 games with him starting, but he did give up 5 earned runs in his last start and that has been a bit of a common theme over the last month. The Mets are going with Holmes in this one and he has been a solid starter all year. He is 11-6 with a 3.60 ERA and hasn't been giving up many runs lately. He is coming off another good start in which he gave up 2 earned runs and the team has won 3 of their last 4 games with him starting too. The Mets can take advantage of this pitching matchup as they are the hotter team right now and still fighting for a playoff spot. The best way to place a bet here is on the Mets to win this game. 

Mets Tigers Prediction:  Our MLB Pick for Wednesday, September 3, 2025 (1:10 pm ET start time) is Mets 5 Tigers 3.

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New York Mets: 20-23 (-11.1 units) on the moneyline against AL Central opponents. 245-230 (-24 units) on the moneyline in all games. 108-128 (-24.3 units) on the moneyline in road games. 23-10 OVER vs. teams outscoring opp by 0.5 or more runs/game on the season.

Detroit Tigers: 248-223 (+30.1 units) on the moneyline in all games. 188-173 (+17.5 units) on the moneyline against right-handed starters. 105-108 (+14.3 units) on the moneyline when playing against a team with a winning record. 23-16 OVER against NL East opponents.

New York Mets:  F. Alvarez (C) Ten Day IL - Thumb. R. Garrett (RP) Fifteen Day IL - Elbow. F. Montas Jr. (SP) Sixty Day IL - Elbow. J. Winker (LF) Sixty Day IL - Back. M. Kranick (RP) Sixty Day IL - Elbow. D. Nunez (RP) Sixty Day IL - Elbow. T. Megill (SP) Sixty Day IL - Elbow. G. Canning (SP) Sixty Day IL - Achilles. J. Siri (CF) Sixty Day IL - Shin. D. Young (RP) Sixty Day IL - Elbow. A. Minter (RP) Sixty Day IL - Lat. C. Scott (SP) Sixty Day IL - Elbow. N. Madrigal (3B) Sixty Day IL - Shoulder. D. Smith (RP) Sixty Day IL - Elbow.

Detroit Tigers:  M. Vierling (CF) Ten Day IL - Oblique. P. Sewald (RP) Sixty Day IL - Shoulder. P. Meadows (CF) Ten Day IL - Quad. R. Olson (SP) Sixty Day IL - Shoulder. S. Guenther (RP) Sixty Day IL - Hip. J. Jobe (SP) Sixty Day IL - Flexor. J. Foley (RP) Sixty Day IL - Shoulder. A. Cobb (SP) Sixty Day IL - Hip. T. Madden (SP) Sixty Day IL - Shoulder. J. Urquidy (SP) Sixty Day IL - Elbow.

“Man, that’s pretty impressive. I don’t think anyone is surprised by it. But when you see it day in and day out for a long period of time, it’s like, ‘Man, this guy can put a team [on his back] and carry it.’ And that’s what he’s doing.” - Carlos Mendoza after his team’s win against the Tigers in their game on Monday.

“The fifth position player does bring up more opportunity to be more aggressive earlier in the game. And one of the things that I’ve seen on our team when we go heavy right-handed or heavy left-handed on the bench, do you have a second move later? If I want to go aggressive earlier in the game with a left-handed hitter, I still have a counter later in the game with all these teams that are coming at us with two and three left-handed relievers. Having that bat at the middle to latter part of the game on a day like today is very useful. We’re going to use our whole roster most days, and adding another bench bat probably only magnifies that.” - A.J. Hinch after his team’s loss against the Mets in their game on Monday.

Francisco Lindor (S) SS

Juan Soto (L) RF

Pete Alonso (R) 1B

Brandon Nimmo (L) LF

Mark Vientos (R) 3B

Jeff McNeil (L) DH

Cedric Mullins (L) CF

Luis Torrens (R) C

Brett Baty (L) 2B

Colt Keith (L) DH

Gleyber Torres (R) 2B

Kerry Carpenter (L) RF

Riley Greene (L) LF

Spencer Torkelson (R) 1B

Wenceel Pérez (S) CF

Zach McKinstry (L) 3B

Dillon Dingler (R) C

Trey Sweeney (L) SS

Batting Average:  Starling Marte (.280)

Hits:  Francisco Lindor (148)

Home Runs:  Juan Soto (36)

RBI:  Pete Alonso (110)

Stolen Bases:  Francisco Lindor (27)

Wins:  Clay Holmes (11)

Saves:  Edwin Díaz (25)

ERA:  Nolan McLean (0.89)

Batting Average:  Brewer Hicklen (.667)

Hits:  Riley Greene (140)

Home Runs:  Riley Greene (32)

RBI:  Riley Greene (101)

Stolen Bases:  Zach McKinstry (19)

Wins:  Casey Mize (12)

Saves:  Will Vest (20)

ERA:  Kyle Finnegan (0.00)

Managers:

New York Mets: Carlos Mendoza (2nd season)

Detroit Tigers: A.J. Hinch (5th season)