New York Jets vs Tampa Bay Buccaneers Prediction, Preview and Odds - 09/21/2025

Game Time: 1:00 pm ET, Sunday, September 21, 2025

Venue:  Raymond James Stadium, Tampa, FL

Where to Watch:  FOX

DraftKings:  Point Spread:  Jets +7, Buccaneers -7; Over/Under:  45.5 points

Bet365:  Point Spread:  Jets +7, Buccaneers -7; Over/Under:  45.5 points

BetMGM:  Point Spread:  Jets +7, Buccaneers -7; Over/Under:  45.5 points

New York Jets:  0-2 (3rd place, AFC East)

Tampa Bay Buccaneers:  2-0 (1st place, NFC South)

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New York Jets:  lost their last game at home against the Buffalo Bills 30-10.

Tampa Bay Buccaneers:  won their last game on the road against the Houston Texans 20-19.

The Jets are entering this game with a 0-2 record overall and they have a 0-1 record in their divisional games too. They are 0-2 in their home games, 0-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against the Buffalo Bills 30-10. Justin Fields was the starting QB and he completed 3/11 passes for 27 passing yards, 0 touchdowns, and 0 interceptions before getting replaced by Tyrod Taylor who completed 7/11 passes for 56 yards and 1 TD. Justin Fields led the team in rushing yards with 49. Garrett Wilson led the receivers with 50 receiving yards on 4 receptions. Jamien Sherwood led the defense in that game with 6 solo tackles and 7 assisted tackles while Jowon Briggs led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.

 

 

 

The Buccaneers are entering this game with a 2-0 record overall and they have a 1-0 record in their divisional games too. They are 0-0 in their home games, 2-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the Houston Texans 20-19. Baker Mayfield was the starting QB and he completed 25/38 passes for 215 passing yards, 2 touchdowns, and 0 interceptions. Bucky Irving led the team in rushing yards with 71. Mike Evans led the receivers with 56 receiving yards on 5 receptions. Tykee Smith led the defense in that game with 4 solo tackles and 2 assisted tackles while Tykee Smith and Greg Gaines III each led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.

The current betting odds have the Buccaneers listed as a 7 point favorite in this game according to Draftkings Sportsbook. The Buccaneers have looked great in their games this season with their 2-0 record overall which has them right at the top of the NFC South. They have been the team to beat in the NFC South the last few years, and they have already pulled off 2 tough road wins to start the season. They got out of Atlanta with a late win in week 1 and they are off another late comeback win against the Texans in their last one. They needed a last second TD to win that one against the Texans, but they were leading for most of that game and were the team in control. The defense looks a lot better than it did last season and even though the offense hasn't looked great yet, they have played 2 really tough defenses and will look better in this home opener. Meanwhile, the Jets haven't looked good in their games this season with their 0-2 record overall. They looked really good in week 1 even though they lost a close game to the Steelers 34-32, but they left everything they had in that game as they are off a 30-10 loss to the Bills at home in their last one and were never even in that game. The offense was terrible as Field couldn't do anything at all, and now they could be without him here, but Taylor didn't look that great when he came in either. The Jets are also supposed to have a much better defense, but they have been getting steamrolled in the first 2 games and this is a good opportunity for the Bucs to have a much needed offensive explosion at home. The best way to place a bet here is on the Buccaneers to cover the spread in this game. 

Jets Buccaneers Prediction:  Our NFL Pick for Sunday, September 21, 2025 (1:00 pm ET start time) is Buccaneers 37 Jets 13.

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New York Jets: 13-22 ATS in all games. 5-10 ATS in road games. 3-8 ATS as an underdog of 3.5 to 9.5 points. 1-8 ATS in non-conference games. 8-3 1H UNDER after allowing 30 points or more last game.

Tampa Bay Buccaneers: 24-15 ATS in all games. 8-3 ATS in non-conference games. 5-1 ATS after a win by 6 or less points. 6-3 UNDER as a home favorite of 7 points or less. 8-3 UNDER at home after 1 or more consecutive wins. 

New York Jets:  T. Adams (S) Injured - Hip. M. Carter II (CB) Injured - Shoulder. J. Fields (QB) Injured - Concussion. J. Johnson (LB) Injured - Ankle. K. Nwangwu (RB) Injured - Hamstring. J. Reynolds (WR) Injured - Hamstring. J. Tufele (DL) Injured - Illness. M. McCrary-Ball (LB) Injured - Hamstring. A. Cisco (S) Injured - Shoulder. S. Gardner (CB) Injured - Groin. K. Mauigoa (LB) Injured - Elbow.

Tampa Bay Buccaneers:  E. Egbuka (WR) Injured - Hip. L. Goedeke (OT) Injured - Foot. C. Kancey (DL) Injured - Pectoral. C. Mauch (OG) Injured - Knee. H. Reddick (LB) Injured - Shoulder. C. Godwin Jr. (WR) Injured - Ankle. T. Wirfs (OT) Injured - Knee. B. Mayfield (QB) Injured - Foot. S. Dennis (LB) Injured - Ankle.

“When it comes to this game, very disappointed. Like, very disappointed. All three phases, to be honest with you.” - Aaron Glenn after his team’s loss against the Bills in their last game. 

“That was a heck of a job of situational football. Baker on the fourth-and-10, using his legs to get the first down. That kind of catapulted everything from there. They did a heck of a job finishing.” - Todd Bowles after his team’s win against the Texans in their last game. 

WR Wilson, Garrett

WR Lazard, Allen

WR Johnson, Tyler

TE Taylor, Mason

QB Taylor, Tyrod

RB Hall, Breece

FB Beck, Andrew

WR Evans, Mike

WR Egbuka, Emeka

WR Shepard, Sterling

TE Otton, Cade

QB Mayfield, Baker

RB Irving, Bucky 

Passing: J. Fields (245)

Rushing: B. Hall (136)

Receiving: G. Wilson (145)

Touchdowns: J. Fields (2)

Passing: B. Mayfield (382)

Rushing: B. Irving (108)

Receiving: M. Evans (107)

Touchdowns: E. Egbuka (3)

Coaches:

New York Jets: Aaron Glenn (1st season)

Tampa Bay Buccaneers: Todd Bowles (4th season)