New York Jets vs Detroit Lions Prediction, Preview and Odds - 09/27/2026

by Rod Pearson

Tuesday, Sep 22, 2026
Game Time: 1:00 pm ET, Sunday, September 27, 2026
Venue:  Ford Field, Detroit, MI
Where to Watch:  FOX


Opening Odds at USA Sportsbooks

DraftKings:  Point Spread:  Jets +6.5, Lions -6.5; Over/Under:  48.5 points
Bet365:  Point Spread:  Jets +6.5, Lions -6.5; Over/Under:  48 points
BetMGM:  Point Spread:  Jets +6.5, Lions -6.5; Over/Under:  48 points

Season Record

New York Jets:  1-1 (2nd place, AFC East)
Detroit Lions:  1-1 (2nd place, NFC North)

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New York Jets:  lost their last game at home against the Green Bay Packers 20-17 in overtime. 
Detroit Lions:  lost their last game on the road against the Buffalo Bills 41-31.


New York Jets vs Detroit Lions Preview and Analysis


The Jets are entering this game with a 1-1 record overall and they have a 0-0 record in their divisional games too. They are 0-1 in their home games, 1-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against the Green Bay Packers 20-17 in OT. Geno Smith was the starting QB and he completed 27/41 passes for 247 passing yards, 1 touchdown, and 0 interceptions. Breece Hall led the team in rushing yards with 29. Breece Hall led the receivers with 63 receiving yards on 5 receptions. Jamien Sherwood and Dane Belton each led the defense in that game with 6 solo tackles while Jowon Briggs, David Bailey, and Kingsley Enagbare each led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.
 
 
 
The Lions are entering this game with a 1-1 record overall and they have a 0-0 record in their divisional games too. They are 1-0 in their home games, 0-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against the Buffalo Bills 41-31. Jared Goff was the starting QB and he completed 26/38 passes for 327 passing yards, 4 touchdowns, and 0 interceptions. Jahmyr Gibbs led the team in rushing yards with 52. Amon-Ra St. Brown led the receivers with 142 receiving yards on 9 receptions and 2 TDs. Chuck Clark led the defense in that game with 11 solo tackles while Derrick Barnes and Aidan Hutchinson each led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.


Jets vs Lions Prediction

The current betting odds have the Lions listed as a 6.5 point favorite in this game according to Draftkings Sportsbook. The Lions haven't looked great in their games this season with their 1-1 record overall so far. They have looked a lot better on their home field though with their 1-0 home record this season. Meanwhile, the Jets haven't looked great in their games this season with their 1-1 record overall so far. They have been a good road team though with their 1-0 road record this year. The Jets are coming off a 20-17 loss to the Packers in OT in their last one and that was a bad collapse on their part. They were in control of that game for 3 quarters as the Packers couldn't do anything, but they fell apart late in the game, letting the Packers come back and go on to win it in OT. They did pick up a road win in week 1, but that was against the Titans who look like one of the worst teams in the NFL again, and that loss to the Packers wasn't great either with the Packers having a lot of trouble in their first 2 games. The Lions haven't looked any better this season as they needed OT just to beat the Saints by 1 point in week 1 and then went on the road and got destroyed by the Bills 41-31. Their defense couldn't stop a thing and put up no resistance to the Bills offense early on which put them in a big hole. They had chances to come back though and the offense has still looked really good in both games this year. They also played that game on the road on a short week, but now they have some extra days to figure out their issues on defense and they will come out with a better performance here. The Jets have looked a lot better in their first 2 games this season, but that offense has still had trouble putting up points and they won't be able to keep up with an angry Lions team looking to bounce back at home. The best way to place a bet here is on the Lions to cover the spread in this game. 

Jets Lions Prediction:  Our NFL Pick for Sunday, September 27, 2026 (1:00 pm ET start time) is Lions 35 Jets 24.
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NFL Betting Trends


New York Jets: 14-20 ATS in all games. 2-8 ATS in non-conference games. 3-8 ATS after a loss by 6 or less points. 4-10 ATS after playing a game at home. 8-4 OVER as a road underdog. 6-3 OVER in a road game where the total is between 42.5 and 49 points. 

Detroit Lions: 17-12 ATS as a favorite. 7-3 ATS after 1 or more consecutive losses. 10-6 ATS after playing their last game on the road. 12-6 ATS in the first half of the regular season. 13-6 OVER as a home favorite. 13-5 OVER in a home game where the total is greater than or equal to 45.5.

Key Injuries


New York Jets:  W. McDonald IV (DL) Questionable - Ankle. J. Sherwood (LB) Injured - Knee. J. Brownlee Jr. (CB) Injured - Shoulder. O. Cooper Jr. (WR) Out - Ankle. M. Fitzpatrick (S) Out - Groin. K. Nwangwu (RB) Out - Back. D. Onyemata (DL) Injured - Rest. J. Ossai (DL) Out - Foot. D. Ponds (CB) Injured - Calf.

Detroit Lions:  D. Reed (CB) Questionable - Foot. B. Miller (OT) Out - Knee. J. Scruggs (OG) Injured - Knee. C. Mahogany (OG) Out - Hip. C. Izien (CB) Injured - Groin.

Notable Quotes


“I'll be honest, I'm highly upset. Tough way to lose a game. There's a number of things that go through my head that, man, we have to fix. This loss is not going to define who we are and what we’re about, I will say that. It’s not OK and our guys are going to take it like that.” - Aaron Glenn after his team’s loss against the Packers in their last game. 


“You play an opponent as potent as this, you don’t have the luxury of spitting and sputtering early. We needed to play. It didn’t have to be spotless, but it certainly needed to be a lot cleaner than that.” - Dan Campbell after his team’s loss against the Bills in their last game. 


Starting Lineups


New York Jets
WR Mitchell, Adonai
WR Wilson, Garrett
WR Williams, Isaiah
TE Taylor, Mason
QB Smith, Geno
RB Hall, Breece
FB Beck, Andrew

Detroit Lions
WR TeSlaa, Isaac
WR Williams, Jameson
WR St. Brown, Amon-Ra
TE LaPorta, Sam
QB Goff, Jared
RB Gibbs, Jahmyr

Statistical Leaders


New York Jets
Passing: Geno Smith (462)
Rushing: Breece Hall (131)
Receiving: Garrett Wilson (136)
Touchdowns: Breece Hall (1)

Detroit Lions
Passing: Jared Goff (533)
Rushing: Jahmyr Gibbs (208)
Receiving: Amon-Ra St. Brown (209)
Touchdowns: Amon-Ra St. Brown (4)

Coaches:
New York Jets: Aaron Glenn (2nd season)
Detroit Lions: Dan Campbell (6th season)


Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

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