New York Giants vs Philadelphia Eagles Prediction, Preview and Odds - 10/26/2025

by Rod Pearson

Tuesday, Oct 21, 2025
Game Time: 1:00 pm ET, Sunday, October 26, 2025
Venue:  Lincoln Financial Field, Philadelphia, PA
Where to Watch:  FOX


Opening Odds at USA Sportsbooks

DraftKings:  Point Spread:  Giants +7, Eagles -7; Over/Under:  43.5 points
Bet365:  Point Spread:  Giants +7, Eagles -7; Over/Under:  43.5 points
BetMGM:  Point Spread:  Giants +7, Eagles -7; Over/Under:  43.5 points

Season Record

New York Giants:  2-5 (4th place, NFC East)
Philadelphia Eagles:  5-2 (1st place, NFC East)

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Recent Form
New York Giants:  lost their last game on the road against the Denver Broncos 33-32.
Philadelphia Eagles:  won their last game on the road against the Minnesota Vikings 28-22.


New York Giants vs Philadelphia Eagles Preview and Analysis


The Giants are entering this game with a 2-5 record overall and they have a 1-2 record in their divisional games too. They are 2-1 in their home games, 0-4 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against the Denver Broncos 33-32. Jaxson Dart was the starting QB and he completed 15/33 passes for 283 passing yards, 3 touchdowns, and 1 interception. Cameron Skattebo led the team in rushing yards with 60. Wan'Dale Robinson led the receivers with 95 receiving yards on 6 receptions. Andru Phillips led the defense in that game with 9 solo tackles and 0 assisted tackles while Brian Burns led the defense in sacks with 2. No one on the defense came away with an interception for them in that one.
 
 
 
The Eagles are entering this game with a 5-2 record overall and they have a 1-1 record in their divisional games too. They are 2-1 in their home games, 3-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the Minnesota Vikings 28-22. Jalen Hurts was the starting QB and he completed 19/23 passes for 326 passing yards, 3 touchdowns, and 0 interceptions. Saquon Barkley led the team in rushing yards with 44. DeVonta Smith led the receivers with 183 receiving yards on 9 receptions and 1 TD. Zack Baun led the defense in that game with 6 solo tackles and 4 assisted tackles while Joshua Uche and Moro Ojomo each led the defense in sacks with 1. Andrew Mukuba and Jalyx Hunt each came away with 1 interception for them in that one.


Giants vs Eagles Prediction

The current betting odds have the Giants listed as a 7 point underdog in this game according to Draftkings Sportsbook. The Giants haven't looked good in their games this season with their 2-5 record overall which has them right near the bottom of the NFC East. They had a terrible start to the season too, but they have looked a lot better since starting Jaxson Dart at QB. They have pulled off some nice upset wins as of late and they are off a 33-32 loss on the road to the Broncos in their last one, a game which they should have won with the lead they had going into the 4th quarter. They will be looking to bounce back after blowing that lead and this is a division rival that they just beat a few weeks ago. Meanwhile, the Eagles have looked great in their games this season with their 5-2 record overall which has them right at the top of the NFC East. They had a great start to the season as they were 4-0 before hitting a snag and losing 2 games in a row, but they bounced back in their last one with a 28-22 win over the Vikings. They looked a lot better in that win and their offense was rolling, but their defense did give the Vikings a way back in that game. This Eagles defense isn't nearly as good as it was last season and the Giants just lit them up a few weeks ago. The Eagles will be looking for some revenge here, but they haven't been blowing any teams out lately and this Giants offense has the talent to keep them in this game. The best way to place a bet here is on the Giants to cover the spread in this game. 

Giants Eagles Prediction:  Our NFL Pick for Sunday, October 26, 2025 (1:00 pm ET start time) is Eagles 27 Giants 24.
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NFL Betting Trends


New York Giants: 3-8 ATS as a road underdog of 7 points or less. 10-17 ATS against conference opponents. 3-7 ATS vs. good passing teams averaging 7 or more passing yards/att. 26-15 UNDER in all games. 13-5 UNDER in all games where the total is between 42.5 and 49 points. 7-2 UNDER after a loss by 6 or less points.

Philadelphia Eagles: 9-3 ATS as a home favorite of 7 points or less. 5-1 ATS revenging a road loss against an opponent. 10-5 ATS after a win by 6 or less points. 5-2 UNDER when playing against a bad team (Win Pct. 25% to 40%). 10-6 UNDER after a win by 6 or less points.

Key Injuries


New York Giants:  P. Adebo (CB) Injured - Knee. B. Burns (LB) Injured - Hip. C. Golston (DL) Injured - Neck. J. Holland (S) Injured - Neck. D. Bellinger (TE) Injured - Neck. S. Bozeman (LB) Injured - Ankle. D. Davidson (DL) Injured - Ankle. J. Eluemunor (OG) Injured - Knee. D. Flannigan-Fowles (LB) Injured - Hamstring. J. Schmitz Jr. (C) Injured - Concussion. D. Slayton (WR) Injured - Hamstring. J. Dart (QB) Injured - Ankle. G. Gano (K) Injured - Groin.

Philadelphia Eagles:  J. Trotter Jr. (LB) Injured - Ankle. J. Bennett (CB) Injured - Pectoral. G. Calcaterra (TE) Injured - Oblique. L. Dickerson (OG) Injured - Ankle. D. Goedert (TE) Injured - Calf. M. Ojomo (DL) Injured - Shoulder. B. Graham (DL) Injured - Not Injury Related. A. Brown (WR) Injured - Hamstring. A. Jackson (CB) Injured - Concussion. C. Jurgens (OG) Injured - Knee. A. Ojulari (LB) Injured - Hamstring.

Notable Quotes


“Tough loss. Put their heart and soul into it. Not a lot of talking that needs to be done when you lose a game like that. Everybody gave everything they had.” - Brian Daboll after his team’s loss against the Broncos in their last game. 


“Every time we get a fourth down conversion, I look at him and I say, ‘Hey, I trust you in these scenarios. Thanks for making me right.’” - Nick Sirianni after his team’s win against the Vikings in their last game. 


Starting Lineups


New York Giants
WR Hyatt, Jalin
WR Humphrey, Lil'Jordan
WR Robinson, Wan'Dale
TE Johnson, Theo
QB Dart, Jaxson
RB Skattebo, Cam

Philadelphia Eagles
WR Brown, A.J. 
WR Dotson, Jahan
WR Smith, DeVonta
TE Goedert, Dallas
QB Hurts, Jalen
RB Barkley, Saquon

Statistical Leaders


New York Giants
Passing: Jaxson Dart (791)
Rushing: Cam Skattebo (398)
Receiving: Wan'Dale Robinson (446)
Touchdowns: Cam Skattebo (6)

Philadelphia Eagles
Passing: Jalen Hurts (1,498)
Rushing: Saquon Barkley (369)
Receiving: DeVonta Smith (504)
Touchdowns: Jalen Hurts (5)

Coaches:
New York Giants: Brian Daboll (4th season)
Philadelphia Eagles: Nick Sirianni (5th season)


Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

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