by Rod Pearson
Friday, Oct 17, 2025
Game Time: 4:05 pm ET, Sunday, October 19, 2025
Venue: Empower Field at Mile High, Denver, CO
Where to Watch: CBS
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Giants +7, Broncos -7; Over/Under: 39.5 points
Bet365: Point Spread: Giants +7, Broncos -7; Over/Under: 40.5 points
BetMGM: Point Spread: Giants +7, Broncos -7; Over/Under: 40.5 points
Season Record
New York Giants: 2-4 (4th place, NFC East)
Denver Broncos: 4-2 (2nd place, AFC West)
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Recent Form
New York Giants: won their last game at home against the Philadelphia Eagles 34-17.
Denver Broncos: won their last game at a neutral site against the New York Jets 13-11.
New York Giants vs Denver Broncos Preview and Analysis
The Giants are entering this game with a 2-4 record overall and they have a 1-2 record in their divisional games too. They are 2-1 in their home games, 0-3 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against the Philadelphia Eagles 34-17. Jaxson Dart was the starting QB and he completed 17/25 passes for 195 passing yards, 1 touchdown, and 0 interceptions. Cameron Skattebo led the team in rushing yards with 98 and 3 TDs. Wan'Dale Robinson led the receivers with 84 receiving yards on 6 receptions and 1 TD. Tyler Nubin led the defense in that game with 6 solo tackles and 3 assisted tackles while Brian Burns led the defense in sacks with 2. Cor'Dale Flott came away with the only interception for them in that one.
The Broncos are entering this game with a 4-2 record overall and they have a 0-1 record in their divisional games too. They are 2-0 in their home games, 2-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the New York Jets 13-11. Bo Nix was the starting QB and he completed 19/30 passes for 174 passing yards, 1 touchdown, and 0 interceptions. J.K. Dobbins led the team in rushing yards with 40. Evan Engram led the receivers with 42 receiving yards on 5 receptions. Alex Singleton led the defense in that game with 5 solo tackles and 2 assisted tackles while Jonathon Cooper led the defense in sacks with 2. No one on the defense came away with an interception for them in that one.
Giants vs Broncos Prediction
The current betting odds have the Giants listed as a 7 point underdog in this game according to Draftkings Sportsbook. The Giants haven't looked good in their games this season with their 2-4 record overall which has them right at the bottom of the NFC East. They had a terrible start to the season where their offense wasn't doing much with Russell Wilson, but they have had a resurgence with Dart as the starter and they have looked a lot better in their games lately. They are off a big win over the defending Super Bowl champions, winning 34-17 over the Eagles on Thursday night, and they have some extra time to rest for this game since they did play last Thursday. Meanwhile, the Broncos have looked good in their games this season with their 4-2 record overall, but they have struggled in quite a few of their games this year. They have been playing in some closer games and they just barely beat the worst team in the NFL in their last one, beating the Jets 13-11 in London. The Broncos are also coming back from London without taking their bye week so they aren't in a great situation here with the travel. The Giants have looked a lot better in their games lately and they are going to have lots of fight in this one, coming off a big win at home. They are catching the Broncos in a bad situation too. The best way to place a bet here is on the Giants to cover the spread in this game.
Giants Broncos Prediction: Our NFL Pick for Sunday, October 19, 2025 (4:05 pm ET start time) is Broncos 20 Giants 17.
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NFL Betting Trends
New York Giants: 3-8 ATS as a road underdog of 7 points or less. 4-13 ATS after playing a game at home. 2-6 ATS versus good rushing teams - averaging 130 rushing yards/game or more. 25-13 UNDER as an underdog. 7-1 UNDER after a game with a turnover margin of +2 or better.
Denver Broncos: 11-6 ATS in all games where the total is between 35.5 and 42 points. 5-0 ATS after scoring 14 points or less last game. 9-2 ATS versus poor rushing defenses - allowing 4.5 rushing yards/carry or more. 4-1 UNDER after scoring 14 points or less last game.
Key Injuries
New York Giants: P. Adebo (CB) Injured - Shoulder. D. Belton (S) Injured - Neck. D. Davidson (DL) Injured - Knee. D. Banks (CB) Injured - NIR - Personal. S. Bozeman (LB) Injured - Ankle. D. Flannigan-Fowles (LB) Injured - Hamstring. J. Schmitz Jr. (C) Injured - Concussion. D. Slayton (WR) Injured - Hamstring. J. Eluemunor (OG) Injured - Shoulder. V. Dimukeje (LB) Injured - Pectoral. C. Golston (DL) Injured - Neck. J. Hyatt (WR) Injured - Ankle. R. Robertson-Harris (DL) Injured - Knee.
Denver Broncos: A. Singleton (LB) Injured - Thumb. D. Greenlaw (LB) Injured - Quad. J. Cooper (LB) Injured - Quad. N. Bonitto (LB) Injured - Wrist. J. Elliss (LB) Injured - Shoulder.
Notable Quotes
“You go through some tough times. Sometimes you can get stronger from it, or sometimes you can fold. I like our guys. These young players, I have a lot of confidence in these young players. These rookies, they have the right mindset. They’re tough.” - Brian Daboll after his team’s win against the Eagles in their last game.
“We had a number of errors. There will be a lot of us that want to clean some stuff up.” - Sean Payton after his team’s win against the Jets in their last game.
Starting Lineups
New York Giants
WR Hyatt, Jalin
WR Collins, Beaux
WR Robinson, Wan'Dale
TE Johnson, Theo
QB Dart, Jaxson
RB Skattebo, Cam
Denver Broncos
WR Sutton, Courtland
WR Mims Jr., Marvin
WR Franklin, Troy
TE Engram, Evan
QB Nix, Bo
RB Dobbins, J.K.
FB Prentice, Adam
Statistical Leaders
New York Giants
Passing: Russell Wilson (786)
Rushing: Cam Skattebo (338)
Receiving: Wan'Dale Robinson (351)
Touchdowns: Cam Skattebo (5)
Denver Broncos
Passing: Bo Nix (1,277)
Rushing: J.K. Dobbins (442)
Receiving: Courtland Sutton (382)
Touchdowns: J.K. Dobbins (4)
Coaches:
New York Giants: Brian Daboll (4th season)
Denver Broncos: Sean Payton (3rd season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
