New Orleans Saints vs Chicago Bears Prediction, Preview and Odds - 10/19/2025

Game Time: 1:00 pm ET, Sunday, October 19, 2025

Venue:  Soldier Field, Chicago, IL

Where to Watch:  FOX

DraftKings:  Point Spread:  Saints +4.5, Bears -4.5; Over/Under:  46.5 points

Bet365:  Point Spread:  Saints +5, Bears -5; Over/Under:  46.5 points

BetMGM:  Point Spread:  Saints +5, Bears -5; Over/Under:  47 points

New Orleans Saints:  1-5 (4th place, NFC South)

Chicago Bears:  3-2 (4th place, NFC North)

Do not miss out on our expert handicapper analysis! Nelly’s Sports is on a HOT STREAK in the NFL on a 15-8 NFL RUN for +$6,230 PROFIT! Make sure you check out his picks and many more from the expert handicappers featured in the Shop Picks section.

New Orleans Saints:  lost their last game at home against the New England Patriots 25-19.

Chicago Bears:  won their last game on the road against the Washington Commanders 25-24.

The Saints are entering this game with a 1-5 record overall and they have a 0-0 record in their divisional games too. They are 1-3 in their home games, 0-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against the New England Patriots 25-19. Spencer Rattler was the starting QB and he completed 20/26 passes for 227 passing yards, 0 touchdowns, and 0 interceptions. Alvin Kamara led the team in rushing yards with 31. Chris Olave led the receivers with 98 receiving yards on 6 receptions. Pete Werner and Alontae Taylor each led the defense in that game with 5 solo tackles and 0 assisted tackles while Pete Werner led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.

 

 

 

The Bears are entering this game with a 3-2 record overall and they have a 0-2 record in their divisional games too. They are 1-1 in their home games, 2-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the Washington Commanders 25-24. Caleb Williams was the starting QB and he completed 17/29 passes for 252 passing yards, 1 touchdown, and 0 interceptions. D'Andre Swift led the team in rushing yards with 108. D'Andre Swift led the receivers with 67 receiving yards on 2 receptions and 1 TD. Tremaine Edmunds led the defense in that game with 4 solo tackles and 9 assisted tackles while Gervon Dexter Sr. led the defense in sacks with 1.5. Jaquan Brisker came away with the only interception for them in that one.

The current betting odds have the Bears listed as a 4.5 point favorite in this game according to Draftkings Sportsbook. The Bears have looked good in their games this season with their 3-2 record overall, but that record still has them right near the bottom of the NFC North. They are in a really competitive division with every team above .500, but the Bears have started to turn things around after a rough start to the year. They started the season 0-2, but now they have won 3 games in a row and they are going to have some momentum on their side after a 25-24 win on the road over the Commanders, the game that essentially ended their season last year. The Bears can build on these wins and now they have a chance to go to 4-2 on the season with a game at home against one of the worst teams in the NFL. Meanwhile, the Saints have looked terrible in their games this season with their 1-5 record overall which has them right at the bottom of the NFC South. They picked up their first win of the season against the Giants the other week, but now they are coming off a 25-19 loss to the Patriots. They have also looked a lot better in their home games this season, but now they are on the road and that defense has looked a lot worse in road games. They aren't going to stop this Bears offense that is starting to click lately and the Bears have also shown some improvement on defense. The best way to place a bet here is on the Bears to cover the spread in this game. 

Saints Bears Prediction:  Our NFL Pick for Sunday, October 19, 2025 (1:00 pm ET start time) is Bears 31 Saints 17.

Don't miss our champion handicappers free picks and expert football picks today. And if you enjoyed this New Orleans Saints Chicago Bears prediction, be sure to drop by every day for our weekly NFL predictions and previews.

New Orleans Saints: 0-5 ATS against NFC North division opponents. 15-24 ATS in all games. 3-8 ATS as an underdog of 3.5 to 9.5 points. 8-2 UNDER vs. bad defensive teams who give up 24 or more points/game. 7-3 UNDER versus poor rushing defenses - allowing 4.5 rushing yards/carry or more.

Chicago Bears: 10-5 ATS in home games. 4-0 ATS after a win by 6 or less points. 6-1 ATS vs. poor teams - outscored by 6+ points per game on the season. 3-0 UNDER after 3 or more consecutive wins against the spread. 6-1 UNDER off an upset win as an underdog. 9-3 UNDER after a game with a turnover margin of +2 or better.

New Orleans Saints:  A. Kamara (RB) Injured - Ankle. I. Yiadom (CB) Injured - Hamstring. C. Olave (WR) Injured - Hip. A. Taylor (CB) Injured - Knee. J. Ridgeway III (DL) Injured - Shoulder.

Chicago Bears:  G. Jarrett (DL) Injured - Knee. C. Santos (K) Injured - Thigh. D. Moore (WR) Injured - Hip. T. Homer (RB) Injured - Calf. J. Jackson (OG) Injured - Ankle. N. Sewell (LB) Injured - Concussion. A. Booker (DL) Injured - Knee.

“We had opportunities — everyone can feel that. I've got to figure out a way to get us there. We’re close. We’re knocking on the door.” - Kellen Moore after his team’s loss against the Patriots in their last game. 

"Over the course there of that second half, there was a little bit of an up and down, with the way the game was going. We hit some adversity and yet that play by 'Swifty,' the 55-yard touchdown, that was really the spark that we needed to reignite us, really the whole team. You felt the defense come back to life again. We were able to come through at the end." - Ben Johnson after his team’s win against the Commanders in their last game. 

WR Olave, Chris

WR Cooks, Brandin

WR Shaheed, Rashid

TE Johnson, Juwan

QB Rattler, Spencer

RB Kamara, Alvin

WR Odunze, Rome

WR Burden III, Luther

WR Zaccheaus, Olamide

TE Kmet, Cole

QB Williams, Caleb

RB Swift, D'Andre

Passing: Spencer Rattler (1,217)

Rushing: Alvin Kamara (314)

Receiving: Chris Olave (342)

Touchdowns: Rashid Shaheed (2)

Passing: Caleb Williams (1,179)

Rushing: D'Andre Swift (295)

Receiving: Rome Odunze (328)

Touchdowns: Rome Odunze (5)

Coaches:

New Orleans Saints: Kellen Moore (1st season)

Chicago Bears: Ben Johnson (1st season)