Missouri Tigers vs Auburn Tigers Prediction, Picks and Game Preview - 10/18/2025

Game Time: 7:45 pm ET, Saturday, October 18, 2025

Venue:  Jordan-Hare Stadium, Auburn University, AL

Where to Watch:  SEC Network

DraftKings:  Point Spread:  Mizzou -1.5, Auburn +1.5; Over/Under:  43.5 points

Bet365:  Point Spread:  Mizzou -1.5, Auburn +1.5; Over/Under:  43.5 points

BetMGM:  Point Spread:  Mizzou -1.5, Auburn +1.5; Over/Under:  43.5 points

Missouri Tigers:  5-1 (1-1) (8th place, SEC)

Auburn Tigers:  3-3 (0-3) (14th place, SEC)

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Missouri Tigers:  lost their last game at home against the Alabama Crimson Tide 27-24.

Auburn Tigers:  lost their last game at home against the Georgia Bulldogs 20-10.

Missouri is entering this game with a 5-1 record overall and they have a 1-1 record in their conference games too. They are 5-1 in their home games, 0-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against Alabama 27-24. Beau Pribula was the starting QB and he completed 16/28 passes for 167 passing yards, 2 touchdowns, and 2 interceptions. Beau Pribula led the team in rushing yards with 61 and 1 TD. Donovan Olugbode led the receivers with 55 receiving yards on 3 receptions and 1 TD. Stephen Hall led the defense in that game with 6 solo tackles and 0 assisted tackles while Damon Wilson II led the defense in sacks with 2. No one on the defense came away with an interception for them in that one.

 

 

 

Auburn is entering this game with a 3-3 record overall and they have a 0-3 record in their conference games too. They are 2-1 in their home games, 1-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against Georgia 20-10. Jackson Arnold was the starting QB and he completed 19/31 passes for 137 passing yards, 0 touchdowns, and 0 interceptions. Jackson Arnold led the team in rushing yards with 55 and 1 TD. Cam Coleman led the receivers with 50 receiving yards on 7 receptions. Xavier Atkins led the defense in that game with 6 solo tackles and 2 assisted tackles while Elijah Melendez and Robert Woodyard Jr. each led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.

The current betting odds have Missouri listed as a 1.5 point favorite in this game according to Draftkings Sportsbook. Missouri has looked really good in their games this season with their 5-1 record overall, but their 1-1 conference record has them right in the middle of the SEC. They haven't really played any good opponents this season and this is going to be their first road game of the year, but they are coming off their first loss of the season and will be looking to bounce back against a weaker team. They are off a 27-24 loss at home to Alabama in their last one, but they played well against one of the better teams in the SEC. Meanwhile, Auburn hasn't looked good in their games this season with their 3-3 record overall and their 0-3 conference record which has them right near the bottom of the SEC. They are off a 20-10 loss at home to Georgia in their last one and their offense hasn't been able to do anything all year. They do have a really good defense that has been keeping them in a lot of their games, but that defense can only do so much if the offense isn't helping out. Auburn has one of the worst offenses in the SEC and even if their defense can slow down this Mizzou offense, Auburn isn't going to be able to put up enough points to keep this game close in the end. Auburn is a disaster at the moment and this is a great game for Missouri to bounce back in after a tight home loss to Alabama. The best way to place a bet here is on Missouri to cover the spread in this game. 

Missouri Auburn Prediction:  Our NCAAF Pick for Saturday, October 18, 2025 (7:45 pm ET start time) is Missouri 27 Auburn 10.

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Missouri Tigers: 22-10 ATS in all lined games. 5-1 ATS when the line is +3 to -3. 5-0 ATS off a loss against a conference rival. 12-6 ATS against conference opponents. 11-6 OVER against conference opponents. 

Auburn Tigers: 3-8 ATS vs. good passing teams averaging 8 or more passing yards/att. 6-12 ATS when playing against a team with a winning record. 4-9 ATS vs. good offensive  teams - scoring 31 or more points/game. 5-2 OVER off a home loss.

Missouri Tigers:  L. Reichert (OG) Questionable - Undisclosed. S. Horn (QB) Out - Leg. B. Craig (K) Out - Undisclosed.

Auburn Tigers:  D. Robinson (RB) Out - Undisclosed. B. Frazier (TE) Questionable - Undisclosed. H. Fields (WR) Out - Foot. B. Deas (LB) Doubtful - Undisclosed. C. Anthony (S) Questionable - Undisclosed.

"We had an opportunity. Proud of the way our defense fought. Proud of the way our offense fought. Ultimately we just had too many critical mistakes in critical situations.” - Eli Drinkwitz after his team’s loss against Alabama in their last game. 

“All you have to do is have the nose of the ball break the plane. It didn’t go our way.” - Hugh Freeze after his team’s loss against Georgia in their last game. 

WR Johnson, Marquis

WR Manning, Joshua

WR Coleman Jr., Kevin

TE Norfleet, Brett

QB Pribula, Beau

RB Hardy, Ahmad

WR Coleman, Cam

WR Singleton Jr., Eric

WR Simmons, Malcolm

TE Frazier, Brandon

QB Arnold, Jackson

RB Cobb, Jeremiah

Passing: Beau Pribula (1,365)

Rushing: Ahmad Hardy (782)

Receiving: Kevin Coleman Jr. (388)

Touchdowns: Ahmad Hardy (9)

Passing: Jackson Arnold (983)

Rushing: Jeremiah Cobb (453)

Receiving: Cam Coleman (305)

Touchdowns: Jackson Arnold (6)

Coaches:

Missouri Tigers: Eli Drinkwitz (6th season)

Auburn Tigers: Hugh Freeze (3rd season)