Michigan Wolverines vs Nebraska Cornhuskers Prediction, Picks and Game Preview - 09/20/2025

Game Time: 3:30 pm ET, Saturday, September 20, 2025

Venue:  Memorial Stadium, Lincoln, NE

Where to Watch:  CBS, Paramount+

DraftKings:  Point Spread:  Michigan -2.5, Nebraska +2.5; Over/Under:  45.5 points

Bet365:  Point Spread:  Michigan -2.5, Nebraska +2.5; Over/Under:  45.5 points

BetMGM:  Point Spread:  Michigan -2.5, Nebraska +2.5; Over/Under:  45.5 points

Michigan Wolverines:  2-1 (0-0) (12th place, Big Ten)

Nebraska Cornhuskers:  3-0 (0-0) (4th place, Big Ten)

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Michigan Wolverines:  won their last game at home against the Central Michigan Chippewas 63-3.

Nebraska Cornhuskers:  won their last game at home against the Houston Christian Huskies 59-7.

Michigan is entering this game with a 2-1 record overall and they have a 0-0 record in their conference games too. They are 2-0 in their home games, 0-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against Central Michigan 63-3. Bryce Underwood was the starting QB and he completed 16/25 passes for 235 passing yards, 1 touchdown, and 1 interception. Bryce Underwood led the team in rushing yards with 114 and 2 TDs. Semaj Morgan led the receivers with 69 receiving yards on 4 receptions and 1 TD. Jaishawn Barham led the defense in that game with 6 solo tackles and 0 assisted tackles while Jaishawn Barham led the defense in sacks with 2. No one on the defense came away with an interception for them in that one.

 

 

 

Nebraska is entering this game with a 3-0 record overall and they have a 0-0 record in their conference games too. They are 2-0 in their home games, 0-0 in their road games, and they are also 1-0 in their neutral site games this season, but they will be at home for this game. They won their last game against Houston Christian 59-7. Dylan Raiola was the starting QB and he completed 15/21 passes for 222 passing yards, 2 touchdowns, and 0 interceptions. Kwinten Ives led the team in rushing yards with 85 and 1 TD. Dane Key led the receivers with 104 receiving yards on 4 receptions and 1 TD. Andrew Marshall led the defense in that game with 4 solo tackles and 1 assisted tackle while Marques Watson-Trent, Riley Van Poppel, and Dasan McCullough each led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.

The current betting odds have Michigan listed as a 2.5 point favorite in this game according to Draftkings Sportsbook. Michigan has looked good in their games this season with their 2-1 record overall. They lost their only road game of the season, but it was against an Oklahoma team that has looked really good to start the season. Now they are off a 63-3 win over Central Michigan and even though they beat up on a MAC opponent, their offense looked it's best all season and they can carry some of that into this game. Meanwhile, Nebraska has looked great in their games this season with their 3-0 record overall, but they also haven't played any good teams yet. They are off a 59-7 win over HCU in their last game and they beat Akron 68-0 the week before, but their only real test this season was a win over Cincinnati and they didn't look great in that one. They barely won that game at a neutral site 20-17 and Cincinnati isn't even a good team in the Big 12 this season. Now they have a ranked Michigan team coming into town who looked terrible in their only road game, but they didn't let Underwood show his true talent against that Oklahoma defense. They are going to unleash Underwood in this game like they did last week and that Nebraska offense is going to struggle a lot more against this Michigan defense like they did in week 1 against Cincinnati. The best way to place a bet here is on Michigan to cover the spread in this game. 

Michigan Nebraska Prediction:  Our NCAAF Pick for Saturday, September 20, 2025 (3:30 pm ET start time) is Michigan 27 Nebraska 17.

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Michigan Wolverines: 12-6 ATS against conference opponents. 8-4 ATS after allowing 14 points or less last game. 5-1 ATS after scoring 37 points or more last game. 6-2 UNDER off a home win by 17 points or more. 8-3 UNDER when playing against a top-level team (Win Pct. > 75%).

Nebraska Cornhuskers: 1-4 ATS vs. good offensive  teams - scoring 31 or more points/game. 1-4 ATS vs. good defensive teams who give up 17 or less points/game. 2-5 ATS when playing against a team with a winning record. 6-3 UNDER when playing against a team with a winning record. 6-2 UNDER versus good rushing teams - averaging 4.75 rushing yards/carry or more.

Michigan Wolverines:  D. Warren (QB) Questionable - Knee. J. Volker (RB) Questionable - Undisclosed. I. Stewart (WR) Questionable - Undisclosed. B. Norton (OG) Questionable - Undisclosed. T. Metcalf (CB) Questionable - Undisclosed. M. Ka'apana (RB) Questionable - Undisclosed. D. Johnson (RB) Questionable - Undisclosed. J. Hood (LB) Questionable - Undisclosed. G. El-Hadi (OG) Questionable - Undisclosed. C. Charleston (WR) Questionable - Undisclosed. D. Baxter (DL) Questionable - Undisclosed. C. Anderson (CB) Questionable - Undisclosed. Z. Berry (CB) Questionable - Undisclosed. I. Iwunnah (DL) Questionable - Undisclosed. R. Moore (CB) Questionable - Undisclosed. M. Keene (QB) Questionable - Undisclosed. A. Babalola (OG) Out - Knee.

Nebraska Cornhuskers:  M. Simpson (DL) Questionable - Undisclosed. T. Terry (DL) Questionable - Undisclosed. J. Parker (RB) Questionable - Undisclosed. J. Jones (WR) Questionable - Undisclosed. J. Marks (OG) Questionable - Undisclosed. T. Uhlir (RB) Questionable - Undisclosed. N. Fennessy (OG) Questionable - Undisclosed. C. Connealy (DL) Questionable - Undisclosed. D. Bell (WR) Questionable - Knee. J. Bonner (WR) Questionable - Undisclosed. G. Brix (OG) Questionable - Undisclosed. J. Rhett (CB) Questionable - Undisclosed. M. Hartzog Jr. (CB) Questionable - Undisclosed. J. Wright (LB) Questionable - Undisclosed. G. Pyle (OG) Out - Knee. B. Hill (CB) Out - Knee. G. Stenger (LB) Out - Undisclosed. M. Markway (TE) Out - Knee.

“I just realized how much of a difference I can make if I use my legs.” - Bryce Underwood after their win against CMU in their last game. 

“We're significantly better than we have been, but the road gets a lot harder. If we stay where we are right now, we won’t win a lot of games going forward. We have to improve.” - Matt Rhule after his team’s win against HCU in their last game. 

WR McCulley, Donaven

WR Goodwin, Channing

WR Morgan, Semaj

TE Klein, Marlin

QB Underwood, Bryce

RB Haynes, Justice

WR Hunter, Nyziah

WR Key, Dane

WR Barney Jr., Jacory

TE Lindenmeyer, Luke

QB Raiola, Dylan

RB Johnson, Emmett

Passing: B. Underwood (628)

Rushing: J. Haynes (388)

Receiving: D. McCulley (158)

Touchdowns: J. Haynes (5)

Passing: D. Raiola (829)

Rushing: E. Johnson (326)

Receiving: D. Key (190)

Touchdowns: E. Johnson (5)

Coaches:

Michigan Wolverines: Sherrone Moore (2nd season)

Nebraska Cornhuskers: Matt Rhule (3rd season)