Miami Dolphins vs Carolina Panthers Prediction, Preview and Odds - 10/05/2025

Game Time: 1:00 pm ET, Sunday, October 5, 2025

Venue:  Bank of America Stadium, Charlotte, NC

Where to Watch:  FOX

DraftKings:  Point Spread:  Dolphins +1.5, Panthers -1.5; Over/Under:  45.5 points

Bet365:  Point Spread:  Dolphins +1.5, Panthers -1.5; Over/Under:  45 points

BetMGM:  Point Spread:  Dolphins +1, Panthers -1; Over/Under:  44.5 points

Miami Dolphins:  1-3 (3rd place, AFC East)

Carolina Panthers:  1-3 (3rd place, NFC South)

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Miami Dolphins:  won their last game at home against the New York Jets 27-21.

Carolina Panthers:  lost their last game on the road against the New England Patriots 42-13.

The Dolphins are entering this game with a 1-3 record overall and they have a 1-2 record in their divisional games too. They are 1-1 in their home games, 0-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against the New York Jets 27-21. Tua Tagovailoa was the starting QB and he completed 17/25 passes for 177 passing yards, 2 touchdowns, and 0 interceptions. De’Von Achane led the team in rushing yards with 99 and 1 TD. Tyreek Hill led the receivers with 67 receiving yards on 6 receptions. Jordyn Brooks led the defense in that game with 15 solo tackles and 3 assisted tackles while Tyrel Dodson and Rasul Douglas each led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.

 

 

 

The Panthers are entering this game with a 1-3 record overall and they have a 1-0 record in their divisional games too. They are 1-0 in their home games, 0-3 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against the New England Patriots 42-13. Bryce Young was the starting QB and he completed 18/30 passes for 150 passing yards, 1 touchdown, and 0 interceptions. Chuba Hubbard led the team in rushing yards with 49. Tetairoa McMillan led the receivers with 62 receiving yards on 4 receptions. Nick Scott led the defense in that game with 4 solo tackles and 2 assisted tackles while Tershawn Wharton led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.

The current betting odds have the Dolphins listed as a 1.5 point underdog in this game according to Draftkings Sportsbook. The Dolphins have looked terrible in their games this season with their 1-3 record overall. They are finally off their first win of the season though and that should give them some momentum now. They started the season with some bad games, but they didn't look as bad in their loss to the Bills in week 3. They built on that performance and finally broke through with a win on Monday night. Meanwhile, the Panthers have looked terrible in their games this season with their 1-3 record overall. They also had a terrible start to the season and finally got their first win in week 3 with a 30-0 home win over the Falcons, but everything they did in that game went down the drain last week when they went to New England and lost 42-13. Their defense was terrible in that loss and their offense couldn't do anything either. They did look a lot better in their only home game this season, but this is one of the worst teams in the NFL with a lot of issues still. The Dolphins have looked terrible this year and are in a bad situation here, but they have looked better over the last 2 weeks and they still have a lot more talent than the Panthers. The best way to place a bet here is on the Dolphins to cover the spread in this game. 

Dolphins Panthers Prediction:  Our NFL Pick for Sunday, October 5, 2025 (1:00 pm ET start time) is Dolphins 31 Panthers 17.

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Miami Dolphins: 8-1 ATS vs. poor passing teams averaging 5.7 or less passing yards/att. 12-5 ATS when playing against a team with a losing record. 8-3 ATS versus poor defensive teams - allowing 5.65 yards/play or more. 13-4 OVER when playing against a team with a losing record. 

Carolina Panthers: 14-22 ATS in all games. 4-10 ATS after allowing 30 points or more last game. 2-8 ATS vs. poor passing defenses - allowing 7 or more passing yards/att. 13-7 OVER in all games where the total is between 42.5 and 49 points. 

Miami Dolphins:  S. Duck (CB) Injured - Ankle. D. Waller (TE) Injured - Hip. J. Brooks (LB) Injured - Elbow. J. Savaiinaea (OG) Injured - Knee. E. Bonner (CB) Injured - Hamstring.

Carolina Panthers:  D. Wonnum (LB) Injured - Hip. P. Jones II (LB) Injured - Hamstring. C. Jackson (DL) Injured - Knee. X. Legette (WR) Injured - Hamstring. C. Mays (C) Injured - Knee. T. McMillan (WR) Injured - Calf. L. Ray (DL) Injured - Ankle. C. Hubbard (RB) Injured - Calf. T. Moton (OT) Injured - NIR - Rest. J. Sanders (TE) Injured - Ankle. T. Wharton (DL) Injured - Toe. C. Smith-Wade (CB) Injured - Chest.

“He was probably in the best spirits of any player that I’ve ever seen (have) such a terrible experience. He immediately had wide eyes and was talking, ‘I’m good, just make sure the guys get this win.’ He was focused on the team.” - Mike McDaniel on the injury to Tyreek Hill after his team’s win against the Jets in their last game. 

“It’s on me. It’s on everybody in that locker room. We talked about that after. We all take accountability. We all have to look in the mirror. We all have to understand what we can do better.” - Bryce Young after their loss against the Patriots in their last game. 

WR Waddle, Jaylen

WR Westbrook-Ikhine, Nick

WR Washington, Malik

TE Waller, Darren

QB Tagovailoa, Tua

RB Achane, De'Von

FB Ingold, Alec

WR McMillan, Tetairoa

WR Renfrow, Hunter

WR Horn Jr., Jimmy

TE Tremble, Tommy

QB Young, Bryce

RB Hubbard, Chuba

Passing: Tua Tagovailoa (752)

Rushing: De'Von Achane (246)

Receiving: Tyreek Hill (265)

Touchdowns: De'Von Achane (3)

Passing: Bryce Young (753)

Rushing: Chuba Hubbard (217)

Receiving: Tetairoa McMillan (278)

Touchdowns: Chuba Hubbard (2)

Coaches:

Miami Dolphins: Mike McDaniel (4th season)

Carolina Panthers: Dave Canales (2nd season)