Memphis Tigers vs UAB Blazers Prediction, Picks and Game Preview - 10/18/2025

Game Time: 4:00 pm ET, Saturday, October 18, 2025

Venue:  Protective Stadium, Birmingham, AL

Where to Watch:  ESPN2

DraftKings:  Point Spread:  Memphis -21.5, UAB +21.5; Over/Under:  63.5 points

Bet365:  Point Spread:  Memphis -21.5, UAB +21.5; Over/Under:  63.5 points

BetMGM:  Point Spread:  Memphis -21.5, UAB +21.5; Over/Under:  63.5 points

Memphis Tigers:  6-0 (2-0) (2nd place, American)

UAB Blazers:  2-4 (0-3) (12th place, American)

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Memphis Tigers:  won their last game at home against the Tulsa Golden Hurricane 45-7.

UAB Blazers:  lost their last game on the road against the Florida Atlantic Owls 53-33.

Memphis is entering this game with a 6-0 record overall and they have a 2-0 record in their conference games too. They are 3-0 in their home games, 3-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against Tulsa 45-7. Brendon Lewis was the starting QB and he completed 22/30 passes for 266 passing yards, 3 touchdowns, and 2 interceptions. Brendon Lewis led the team in rushing yards with 67 and 1 TD. Jamari Hawkins led the receivers with 110 receiving yards on 7 receptions. Kamari Wilson led the defense in that game with 5 solo tackles and 3 assisted tackles while no one on the defense recorded a sack for them. Kamari Wilson, Samson Israel, and Chris Bracy each came away with 1 interception for them in that one.

 

 

 

UAB is entering this game with a 2-4 record overall and they have a 0-3 record in their conference games too. They are 2-1 in their home games, 0-3 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against FAU 53-33. Jalen Kitna was the starting QB and he completed 29/41 passes for 261 passing yards, 1 touchdown, and 0 interceptions. Solomon Beebe led the team in rushing yards with 34 and 2 TDs. Solomon Beebe led the receivers with 63 receiving yards on 6 receptions. Pierre Royster led the defense in that game with 5 solo tackles and 1 assisted tackle while no one on the defense recorded a sack for them. Devin Hightower came away with the only interception for them in that one.

The current betting odds have Memphis listed as a 21.5 point favorite in this game according to Draftkings Sportsbook. Memphis has looked great in their games this season with their 6-0 record overall and their 2-0 conference record which has them right near the top of the American Conference. They are off a 45-7 win over Tulsa in their last one and not only have they emerged as a threat to win the conference this season, they have also emerged as a threat to earn that group of 5 playoff spot. Their offense has been rolling over teams this season too and this is another game where they will be able to put up a ton of points. Meanwhile, UAB hasn't looked good in their games this season with their 2-4 record overall and their 0-3 conference record which has them right near the bottom of the American Conference. They have one of the worst defenses in the conference with the points they have been giving up this season, and they just fired their head coach with the disaster that they have been this year. Their offense has looked good as they have been putting up points in their games, but they are off a 53-33 loss to FAU in their last one as their defense just can't keep games close. This is also a much better Memphis defense they will be facing so this offense isn't going to look nearly as good in this 1st game with their head coach now gone. The best way to place a bet here is on Memphis to cover the spread in this game. 

Memphis UAB Prediction:  Our NCAAF Pick for Saturday, October 18, 2025 (4:00 pm ET start time) is Memphis 56 UAB 13.

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Memphis Tigers: 8-4 ATS in road lined games. 6-0 ATS off a home win by 17 points or more. 10-5 ATS after playing a game at home. 20-11 OVER in all lined games. 5-0 OVER when the total is between 63.5 and 70. 12-1 OVER off a win against a conference rival. 

UAB Blazers: 5-10 ATS against conference opponents. 2-6 ATS vs. good offensive  teams - scoring 31 or more points/game. 3-7 ATS versus good offensive teams - averaging 425 yards/game or more. 16-8 OVER in all lined games. 14-5 OVER as an underdog. 8-4 OVER after a loss by 17 or more points.

Memphis Tigers:  C. Law (LB) Out - Undisclosed. K. Marsh (CB) Out - Undisclosed.

UAB Blazers:  P. Kirkland (OG) Questionable - Undisclosed. D. Smith (DL) Questionable - Undisclosed. N. Ramirez (OG) Questionable - Undisclosed. C. Milliner (WR) Questionable - Personal. L. Brayton (WR) Questionable - Undisclosed. M. Chorak (OG) Questionable - Undisclosed. P. Simmons (DL) Questionable - Undisclosed. J. Judson (CB) Questionable - Undisclosed. T. Crumpley (CB) Questionable - Undisclosed. L. Kirby (S) Questionable - Undisclosed. D. Patterson (RB) Questionable - Undisclosed. N. Tate (DL) Questionable - Undisclosed. E. Lagg (TE) Questionable - Undisclosed. D. Warren (DL) Questionable - Undisclosed.

"We've got to continue to do a better job taking care of the football. Even this past game, a couple interceptions. They could've been the fault of the quarterback, the fault of the offensive line, receivers got to make plays on the ball. We've seen some fumbles come out. Even Greg (Desrosiers), the ball hit the ground, can't have that. Happened to Sutton (Smith) the week before.” - Ryan Silverfield on his team this season. 

“I certainly want to thank (Athletic Director) Mark Ingram for expressing the confidence in me and our administration to do this for the remainder of the season. It’s obviously not the circumstances with which I would want this to happen, but I’m certainly grateful.” - Alex Mortensen on being named the interim head coach after Trent Dilfer was fired.

WR Braham Jr., Cortez

WR Bussey, Marcello

WR Hawkins, Jamari

TE Ross, Christian

QB Lewis, Brendon

RB Desrosiers Jr., Greg

WR Milliner, Corri

WR Hooks, Iverson

WR Hawkins Jr., Brandon

TE Sivley, J.C.

QB Kitna, Jalen

RB Jackson, Jevon

Passing: Brendon Lewis (1,269)

Rushing: Sutton Smith (454)

Receiving: Cortez Braham Jr. (408)

Touchdowns: Brendon Lewis (7)

Passing: Jalen Kitna (1,776)

Rushing: Jevon Jackson (388)

Receiving: Iverson Hooks (388)

Touchdowns: Solomon Beebe (4)

Coaches:

Memphis Tigers: Ryan Silverfield (6th season)

UAB Blazers: Alex Mortensen (Interim)