Los Angeles Rams vs Seattle Seahawks Prediction, Preview and Odds - 12/18/2025

by Rod Pearson

Tuesday, Dec 16, 2025
Game Time: 8:15 pm ET, Thursday, December 18, 2025
Venue:  Lumen Field, Seattle, WA 
Where to Watch:  Prime Video


Opening Odds at USA Sportsbooks

DraftKings:  Point Spread:  Rams +1.5, Seahawks -1.5; Over/Under:  44.5 points
Bet365:  Point Spread:  Rams -1, Seahawks +1; Over/Under:  44 points
BetMGM:  Point Spread:  Rams -1, Seahawks +1; Over/Under:  44 points

Season Record

Los Angeles Rams:  11-3 (1st place, NFC West)
Seattle Seahawks:  11-3 (2nd place, NFC West)

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Recent Form
Los Angeles Rams:  won their last game at home against the Detroit Lions 41-34. 
Seattle Seahawks:  won their last game at home against the Indianapolis Colts 18-16.


Los Angeles Rams vs Seattle Seahawks Preview and Analysis


The Rams are entering this game with an 11-3 record overall and they have a 3-1 record in their divisional games too. They are 6-1 in their home games, 4-2 in their road games, and they are also 1-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against the Detroit Lions 41-34. Matthew Stafford was the starting QB and he completed 24/38 passes for 368 passing yards, 2 touchdowns, and 1 interception. Kyren Williams led the team in rushing yards with 78 and 2 TDs. Puka Nacua led the receivers with 181 receiving yards on 9 receptions. Nate Landman led the defense in that game with 6 solo tackles and 4 assisted tackles while Kobie Turner led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.
 
 
 
The Seahawks are entering this game with an 11-3 record overall and they have a 2-2 record in their divisional games too. They are 5-2 in their home games, 6-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the Indianapolis Colts 18-16. Sam Darnold was the starting QB and he completed 22/36 passes for 271 passing yards, 0 touchdowns, and 0 interceptions. Zach Charbonnet led the team in rushing yards with 31. Jaxon Smith-Njigba led the receivers with 113 receiving yards on 7 receptions. Nick Emmanwori led the defense in that game with 6 solo tackles and 1 assisted tackle while Nick Emmanwori led the defense in sacks with 1. Coby Bryant came away with the only interception for them in that one.


Rams vs Seahawks Prediction

The current betting odds have the Rams listed as a 1.5 point underdog in this game according to Draftkings Sportsbook. The Rams have looked great in their games this season with their 11-3 record overall which has them right at the top of the NFC West with one of the best records in the entire NFL. They have been a good road team too with their 4-2 road record this year. Meanwhile, the Seahawks have looked great in their games this season with their 11-3 record overall which has them right near the top of the NFC West with one of the best records in the entire NFL. They have looked great on their home field too with their 5-2 home record this year. The Seahawks have been rolling over teams all year with a lot of double digits wins under their belt and one of the best defenses in the NFL too. As good as they have been though, their offense has looked really up and down at times. They are off an 18-16 win over the Colts in their last one, needing 6 field goals to beat a Philip Rivers led Colts team, and Sam Darnold didn't look great. He has had games like this from time to time all season, and he has had a big issue against the Rams going back to last season too. The Rams are off a 41-34 win over the Lions in their last one and they have also been rolling over teams all year. They have one of the best offenses in the NFL and are starting to look like the best team this year. They already beat the Seahawks a few weeks ago and will be looking to do so again with division implications on the line. Darnold also can't be trusted against this Rams defense that he has had issues against over the last year. The best way to place a bet here is on the Rams to cover the spread in this game. 

Rams Seahawks Prediction:  Our NFL Pick for Thursday, December 18, 2025 (8:15 pm ET start time) is Rams 21 Seahawks 17.
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NFL Betting Trends


Los Angeles Rams: 31-18 ATS in all games. 16-8 ATS in road games. 7-1 ATS after allowing 30 points or more last game. 12-5 ATS vs. good offensive teams - scoring 24 or more points/game. 8-3 OVER vs. good teams - outscoring opponents by 6+ PPG on the season. 11-4 OVER off a home win.

Seattle Seahawks: 9-15 ATS in home games. 5-11 ATS in a home game where the total is between 42.5 and 49 points. 0-3 ATS revenging a road loss against an opponent. 10-2 OVER as a home favorite of 7 points or less. 

Key Injuries


Los Angeles Rams:  N. Vannett (TE) Injured - Oblique. J. Whittington (WR) Injured - Back. B. Fiske (DL) Injured - Ankle. J. McCollough (S) Injured - Illness. A. Jackson (OG) Injured - Ankle. D. Adams (WR) Injured - Knee.

Seattle Seahawks:  A. Lucas (OT) Injured - Neck. D. Hall (LB) Injured - Finger. C. Cross (OT) Injured - Hamstring. M. Morris (DL) Injured - Knee. D. Lawrence (LB) Injured - Quadricep. J. Reed (DL) Injured - Wrist. L. Williams (DL) Injured - Wrist. C. White (WR) Injured - Abdomen. D. Young (WR) Injured - Quadricep. T. Okada (S) Injured - Shoulder.

Notable Quotes


“When we're firing on all cylinders ... man. You put your foot on the gas, and you leave everybody behind.” - Kobie Turner after their win against the Lions in their last game. 


“It means a lot. Taking care of my body and making sure I’m here for my teammates, that’s what I want to do. Honestly, I could care less about any stat right now. I just want to win.” - Jaxon Smith-Njigba after their win against the Colts in their last game. 


Starting Lineups


Los Angeles Rams
WR Adams, Davante
WR Nacua, Puka
WR Atwell, Tutu
TE Parkinson, Colby
QB Stafford, Matthew
RB Williams, Kyren

Seattle Seahawks
WR Smith-Njigba, Jaxon
WR Shaheed, Rashid
WR Kupp, Cooper
TE Barner, AJ 
QB Darnold, Sam
RB Walker III, Kenneth
FB Russell, Brady

Statistical Leaders


Los Angeles Rams
Passing: Matthew Stafford (3,722)
Rushing: Kyren Williams (1,030)
Receiving: Puka Nacua (1,367)
Touchdowns: Davante Adams (14)

Seattle Seahawks
Passing: Sam Darnold (3,433)
Rushing: Kenneth Walker III (779)
Receiving: Jaxon Smith-Njigba (1,541)
Touchdowns: Jaxon Smith-Njigba (9)

Coaches:
Los Angeles Rams: Sean McVay (9th season)
Seattle Seahawks: Mike Macdonald (2nd season)


Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

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