by Rod Pearson
Thursday, Oct 01, 2026
Game Time: 4:25 pm ET, Sunday, October 4, 2026
Venue: Lumen Field, Seattle, WA
Where to Watch: CBS
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Chargers +7, Seahawks -7; Over/Under: 42.5 points
Bet365: Point Spread: Chargers +7, Seahawks -7; Over/Under: 42.5 points
BetMGM: Point Spread: Chargers +7, Seahawks -7; Over/Under: 42.5 points
Season Record
Los Angeles Chargers: 0-3 (4th place, AFC West)
Seattle Seahawks: 2-1 (2nd place, NFC West)
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Los Angeles Chargers: lost their last game on the road against the Buffalo Bills 24-16.
Seattle Seahawks: lost their last game on the road against the Washington Commanders 33-31.
Los Angeles Chargers vs Seattle Seahawks Preview and Analysis
The Chargers are entering this game with a 0-3 record overall and they have a 0-1 record in their divisional games too. They are 0-2 in their home games, 0-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against the Buffalo Bills 24-16. Justin Herbert was the starting QB and he completed 20/34 passes for 226 passing yards, 1 touchdown, and 1 interception. Omarion Hampton led the team in rushing yards with 56. Tre Harris led the receivers with 76 receiving yards on 6 receptions. Daiyan Henley led the defense in that game with 9 solo tackles while Tuli Tuipulotu led the defense in sacks with 1.5. Genesis Smith came away with 2 interceptions for them in that one.
The Seahawks are entering this game with a 2-1 record overall and they have a 1-0 record in their divisional games too. They are 1-0 in their home games, 1-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against the Washington Commanders 33-31. Sam Darnold was the starting QB and he completed 31/45 passes for 379 passing yards, 4 touchdowns, and 2 interceptions. Jadarian Price led the team in rushing yards with 15. Jaxon Smith-Njigba led the receivers with 128 receiving yards on 10 receptions and 2 TDs. Drake Thomas led the defense in that game with 9 solo tackles while Derick Hall and Leonard Williams each led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.
Chargers vs Seahawks Prediction
The current betting odds have the Chargers listed as a 7 point underdog in this game according to Draftkings Sportsbook. The Chargers have looked terrible in their games this season with their 0-3 record overall which has them right at the bottom of the AFC West. They haven't been a good road team either with their 0-1 road record this year. Meanwhile, the Seahawks have looked good in their games this season with their 2-1 record overall which has them right near the top of the NFC West. They have looked great on their home field too with their 1-0 home record this season. The Seahawks are the defending Super Bowl champions and still have one of the best defenses in the NFL, but the offense has definitely been an issue for them. It hasn't helped that they lost Sam Darnold in their season opener, but the offense has been having trouble with a new OC this season and Kenneth Walker no longer being with the team. Darnold came back last week and the offense looked a lot better, but they had no rushing attack and ended up losing to the Commanders 33-31. The defense didn't look great in that one either and they will be looking to bounce back here, but they also have one of the most desperate teams in the NFL coming into town. The Chargers are coming off a 24-16 loss to the Bills in their last one, but they actually played their best game of the season. They were leading the Bills for a lot of that game and even caused 5 turnovers, but it wasn't enough to get them the win. They still have a ton of talent on their roster though and have been a playoff team the last few years, so they are going to bring their best effort in this game and throw everything they have at the Seahawks to get a win. This is a dangerous situation for the Seahawks against a really desperate team, especially since the Seahawks haven't looked like that team from last year. The best way to place a bet here is on the Chargers to cover the spread in this game.
Chargers Seahawks Prediction: Our NFL Pick for Sunday, October 4, 2026 (4:25 pm ET start time) is Seahawks 24 Chargers 20.
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NFL Betting Trends
Los Angeles Chargers: 24-37 ATS vs. good passing defenses - allowing 5.7 or less passing yards/att. 26-34 ATS versus good rushing defenses - allowing 90 rushing yards/game or less. 23-16 UNDER in all games. 8-2 UNDER in a road game where the total is between 42.5 and 49 points. 6-3 UNDER after a game with a turnover margin of +2 or better.
Seattle Seahawks: 22-15 ATS in all games. 15-8 ATS as a favorite. 9-4 ATS after scoring 30 points or more last game. 9-4 UNDER after scoring 30 points or more last game.
Key Injuries
Los Angeles Chargers: K. Mack (LB) Injured - Rest. D. Tomlinson (DL) Injured - Hamstring. D. James Jr. (S) Injured - Hamstring. D. Jackson (CB) Injured - Concussion. K. Awosika (OG) Injured - Fibula. C. Kolar (TE) Injured - Forearm. E. Molden (CB) Injured - Hamstring. K. Mitchell (RB) Injured - Ankle. T. Lance (QB) Injured - Groin. J. Eboigbe (DL) Injured - Eye. L. McConkey (WR) Injured - Foot. B. Thompson (WR) Injured - Quadricep.
Seattle Seahawks: J. Reed (DL) Injured - Foot. L. Williams (DL) Injured - Rest. B. Pili (DL) Injured - Neck. R. Shaheed (WR) Injured - Hip. J. Love (S) Injured - Calf. T. Okada (S) Injured - Hamstring. G. Holani (RB) Injured - Rib. G. Zabel (OG) Injured - Groin. N. Emmanwori (S) Injured - Ankle. J. Price (RB) Injured - Chest.
Notable Quotes
“We did not win the game. That’s painful. That hurts. There was a lot of opportunity. And we’ve got to capitalize on that. We have to be better.” - Jim Harbaugh after his team’s loss against the Bills in their last game.
“They got to an audible against zero. They made a good check, and we didn't make the play.” - Mike Macdonald after his team’s loss against the Commanders in their last game.
Starting Lineups
Los Angeles Chargers
WR Johnston, Quentin
WR Harris, Tre'
WR McConkey, Ladd
TE Gadsden, Oronde
QB Herbert, Justin
RB Hampton, Omarion
FB Ingold, Alec
Seattle Seahawks
WR Smith-Njigba, Jaxon
WR Shaheed, Rashid
WR Kupp, Cooper
TE Barner, AJ
QB Darnold, Sam
RB Price, Jadarian
FB Russell, Brady
Statistical Leaders
Los Angeles Chargers
Passing: Justin Herbert (627)
Rushing: Omarion Hampton (193)
Receiving: Ladd McConkey (183)
Touchdowns: Omarion Hampton (2)
Seattle Seahawks
Passing: Drew Lock (422)
Rushing: Jadarian Price (119)
Receiving: Jaxon Smith-Njigba (405)
Touchdowns: Jaxon Smith-Njigba (6)
Coaches:
Los Angeles Chargers: Jim Harbaugh (3rd season)
Seattle Seahawks: Mike Macdonald (3rd season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
