by Rod Pearson
Wednesday, Oct 22, 2025
Game Time: 3:30 pm ET, Saturday, October 25, 2025
Venue: Husky Stadium, Seattle, WA
Where to Watch: Big Ten Network
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Illinois +4.5, Washington -4.5; Over/Under: 53.5 points
Bet365: Point Spread: Illinois +4.5, Washington -4.5; Over/Under: 54 points
BetMGM: Point Spread: Illinois +4.5, Washington -4.5; Over/Under: 53.5 points
Season Record
Illinois Fighting Illini: 5-2 (2-2) (12th place, Big Ten)
Washington Huskies: 5-2 (2-2) (11th place, Big Ten)
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Recent Form
Illinois Fighting Illini: lost their last game at home against the Ohio State Buckeyes 34-16.
Washington Huskies: lost their last game on the road against the Michigan Wolverines 24-7.
Illinois Fighting Illini vs Washington Huskies Preview and Analysis
Illinois is entering this game with a 5-2 record overall and they have a 2-2 record in their conference games too. They are 3-1 in their home games, 2-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against Ohio State 34-16. Luke Altmyer was the starting QB and he completed 30/44 passes for 248 passing yards, 1 touchdown, and 1 interception. Aidan Laughery led the team in rushing yards with 50 and 1 TD. Cole Rusk led the receivers with 68 receiving yards on 5 receptions. Matthew Bailey led the defense in that game with 7 solo tackles and 1 assisted tackle while no one on the defense recorded a sack for them. No one on the defense came away with an interception for them in that one.
Washington is entering this game with a 5-2 record overall and they have a 2-2 record in their conference games too. They are 3-1 in their home games, 2-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against Michigan 24-7. Demond Williams Jr. was the starting QB and he completed 20/32 passes for 209 passing yards, 0 touchdowns, and 3 interceptions. Jonah Coleman led the team in rushing yards with 50 and 1 TD. Denzel Boston led the receivers with 71 receiving yards on 4 receptions. Makell Esteen led the defense in that game with 8 solo tackles and 0 assisted tackles while Ta'ita'i Uiagalelei led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.
Illinois vs Washington Prediction
The current betting odds have Washington listed as a 4.5 point favorite in this game according to Draftkings Sportsbook. Washington has looked good in their games this season with their 5-2 record overall and their 2-2 conference record which has them right in the middle of the Big Ten. They are off a bad loss to Michigan in their last one, losing 24-7 in a game where they couldn't do much on offense, but they have struggled a lot more in their road games this season. That is their only road loss this year, but they have played in some really tight road games already. They are going to be back at home for this game though and they have been crushing opponents at home all season. Meanwhile, Illinois has looked good in their games this season with their 5-2 record overall and their 2-2 conference record which has them right in the middle of the Big Ten. They are off a bad home loss to Ohio State in their last one and they are coming out of their bye week now so they have had extra time to rest, but this isn't an easy game for them. They are 2-1 in road games this season with wins over Duke and Purdue, but their 1 road loss was 63-10 to Indiana. This is also going to be their first game on the West coast this season so this isn't a great situation for them. Illinois has looked great on offense all season, but their defense has been giving up a ton of points and that will be an issue in this one. Washington has a really good offense that is going to put up points at home and their defense has also looked a lot better at home this season. The best way to place a bet here is on Washington to cover the spread in this game.
Illinois Washington Prediction: Our NCAAF Pick for Saturday, October 25, 2025 (3:30 pm ET start time) is Washington 42 Illinois 28.
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NCAAF Betting Trends
Illinois Fighting Illini: 17-8 ATS in all lined games. 8-4 ATS in road lined games. 10-5 ATS after playing a game at home. 8-3 ATS versus good rushing defenses - allowing 120 rushing yards/game or less. 11-6 UNDER as an underdog. 7-3 UNDER when the total is between 49.5 and 56.
Washington Huskies: 5-10 ATS when the total is between 49.5 and 56. 5-9 ATS vs. good passing teams averaging 8 or more passing yards/att. 11-5 UNDER vs. good passing teams averaging 250 or more passing yards/game. 12-5 UNDER versus good offensive teams - averaging 5.9 yards/play or more.
Key Injuries
Illinois Fighting Illini: B. Clawson (CB) Questionable - Undisclosed. X. Scott (CB) Questionable - Undisclosed. A. Knapik (OG) Questionable - Knee. L. Zardzin (LB) Questionable - Undisclosed. L. Hansen (LS) Questionable - Undisclosed. L. Farrell (TE) Out - Undisclosed. T. Cox (CB) Out - Undisclosed. J. Forster (RB) Out - Undisclosed. J. Hirdes (OG) Out - Knee. G. Smith (TE) Out - Undisclosed.
Washington Huskies: K. Eldridge (TE) Out - Undisclosed. J. Mills (OG) Questionable - Undisclosed. R. Williams (WR) Questionable - Collarbone. C. Christian (S) Questionable - Undisclosed. C. Willis (OG) Questionable - Knee. B. Al-Uqdah (LB) Out - Undisclosed. R. Davis II (DL) Out - Undisclosed. C. Crowell (TE) Out - Undisclosed. D. McCutcheon (S) Out - Undisclosed. R. Wright II (S) Out - Undisclosed.
Notable Quotes
“That first half was about as bad as bad can get. We started off with a turnover and defensively, we couldn’t get off the field on third down. Before you win, you’ve got to stop losing, and we lost that one.” - Bret Bielema after his team’s loss against Ohio State in their last game.
“Just didn’t feel like I did a good enough job getting him ready for the game." - Jedd Fisch after his team’s loss against Michigan in their last game.
Starting Lineups
Illinois Fighting Illini
WR Clement, Hudson
WR Dixon, Collin
WR Beatty, Hank
TE Arkin, Tanner
QB Altmyer, Luke
RB Feagin, Kaden
Washington Huskies
WR Boston, Denzel
WR Roebuck, Dezmen
WR Vines-Bright, Raiden
TE DeGraaf, Decker
QB Williams Jr., Demond
RB Coleman, Jonah
Statistical Leaders
Illinois Fighting Illini
Passing: Luke Altmyer (1,821)
Rushing: Kaden Feagin (338)
Receiving: Hank Beatty (617)
Touchdowns: Kaden Feagin (6)
Washington Huskies
Passing: Demond Williams Jr. (1,837)
Rushing: Jonah Coleman (568)
Receiving: Denzel Boston (515)
Touchdowns: Jonah Coleman (13)
Coaches:
Illinois Fighting Illini: Bret Bielema (5th season)
Washington Huskies: Jedd Fisch (2nd season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
