Houston Texans vs Seattle Seahawks Prediction, Preview and Odds - 10/20/2025

Game Time: 10:00 pm ET, Monday, October 20, 2025

Venue:  Lumen Field, Seattle, WA 

Where to Watch:  ESPN

DraftKings:  Point Spread:  Texans +3, Seahawks -3; Over/Under:  41.5 points

Bet365:  Point Spread:  Texans +3, Seahawks -3; Over/Under:  41 points

BetMGM:  Point Spread:  Texans +3, Seahawks -3; Over/Under:  41 points

Houston Texans:  2-3 (3rd place, AFC South)

Seattle Seahawks:  4-2 (2nd place, NFC West)

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Houston Texans:  won their last game on the road against the Baltimore Ravens 44-10.

Seattle Seahawks:  won their last game on the road against the Jacksonville Jaguars 20-12.

The Texans are entering this game with a 2-3 record overall and they have a 1-1 record in their divisional games too. They are 1-1 in their home games, 1-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against the Baltimore Ravens 44-10. C. J. Stroud was the starting QB and he completed 23/27 passes for 244 passing yards, 4 touchdowns, and 0 interceptions. Nick Chubb led the team in rushing yards with 61 and 1 TD. Christian Kirk led the receivers with 64 receiving yards on 4 receptions. E.J. Speed led the defense in that game with 5 solo tackles and 1 assisted tackle while Mario Edwards Jr. led the defense in sacks with 1. Jalen Pitre came away with 2 interceptions while Kamari Lassiter came away with 1 INT for them in that one.

 

 

 

The Seahawks are entering this game with a 4-2 record overall and they have a 1-1 record in their divisional games too. They are 1-2 in their home games, 3-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the Jacksonville Jaguars 20-12. Sam Darnold was the starting QB and he completed 16/27 passes for 295 passing yards, 2 touchdowns, and 0 interceptions. Kenneth Walker III led the team in rushing yards with 34. Jaxon Smith-Njigba led the receivers with 162 receiving yards on 8 receptions and 1 TD. Shaquill Griffin led the defense in that game with 7 solo tackles and 0 assisted tackles while DeMarcus Lawrence and Byron Murphy II each led the defense in sacks with 2. No one on the defense came away with an interception for them in that one.

The current betting odds have the Seahawks listed as a 3 point favorite in this game according to Draftkings Sportsbook. The Seahawks have looked really good in their games this season with their 4-2 record overall which has them right near the top of the NFC West. They are off a 20-12 win over the Jaguars in their last one and their defense has looked great all season, not giving up many points. Meanwhile, the Texans haven't looked great in their games this season with their 2-3 record overall which has them lower in the AFC South. They started the season 0-3 and they have looked a lot better in their games lately with 2 wins in a row now. They are also coming out of their bye week and their defense has looked great all year too, but their offense has been really up and down. They won their last one against the Ravens 44-10, but they beat up on a banged up Ravens team that couldn't do much on offense. The Texans haven't looked nearly as good offensively in any other game this season and they are going to struggle to put up points on this offense. The Seahawks offense has also been up and down this season, but they have been the more stable offense to start the season and they have the home advantage to lean on too. The best way to place a bet here is on the Seahawks to cover the spread in this game. 

Texans Seahawks Prediction:  Our NFL Pick for Monday, October 20, 2025 (10:00 pm ET start time) is Seahawks 20 Texans 16.

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Houston Texans: 7-0 ATS in a road game where the total is between 35.5 and 42 points. 6-2 ATS after a win by 14 or more points. 11-6 ATS when playing against a team with a winning record. 26-15 UNDER in all games. 9-2 UNDER in non-conference games. 12-6 UNDER after playing their last game on the road.

Seattle Seahawks: 6-14 ATS in home games. 3-7 ATS as a home favorite of 7 points or less. 4-7 ATS when playing against a team with a losing record. 13-4 UNDER in games where the line is +3 to -3. 8-4 UNDER when playing against a team with a losing record.

Houston Texans:  J. Reed (S) Injured - Knee. A. Huzzie (CB) Injured - Knee. D. Autry (DL) Injured - Knee.

Seattle Seahawks:  D. Lawrence (LB) Injured - Rest. J. Reed (DL) Injured - Knee. L. Williams (DL) Injured - Rest. J. Jones (OG) Injured - Ankle. R. Woolen (CB) Injured - Concussion. J. Love (S) Injured - Hamstring. D. Hall (LB) Injured - Oblique. D. Witherspoon (CB) Injured - Knee. N. Pritchett (CB) Injured - Hamstring.

“What I saw from C.J. today was his demeanor — he was very calm, he was very under control the entire game. He didn't get flustered.” - DeMeco Ryans after his team’s win against the Ravens in their last game. 

“That was critical. We knew they would do that going into the game. They’re an opportunistic team. The numbers speak for themselves. I thought our ball security was tremendous.” - Mike Macdonald after his team’s win against the Jaguars in their last game. 

WR Collins, Nico

WR Hutchinson, Xavier

WR Kirk, Christian

TE Schultz, Dalton

QB Stroud, C.J.

RB Marks, Woody

FB Brooks, British

WR Smith-Njigba, Jaxon

WR Horton, Tory

WR Kupp, Cooper

TE Barner, AJ 

QB Darnold, Sam

RB Walker III, Kenneth

FB Russell, Brady

Passing: C.J. Stroud (1,076)

Rushing: Nick Chubb (249)

Receiving: Nico Collins (312)

Touchdowns: Nico Collins (3)

Passing: Sam Darnold (1,541)

Rushing: Kenneth Walker III (364)

Receiving: Jaxon Smith-Njigba (696)

Touchdowns: AJ Barner (4)

Coaches:

Houston Texans: DeMeco Ryans (3rd season)

Seattle Seahawks: Mike Macdonald (2nd season)