Houston Cougars vs Arizona State Sun Devils Prediction, Picks and Game Preview - 10/25/2025

Game Time: 8:00 pm ET, Saturday, October 25, 2025

Venue:  Mountain America Stadium, Tempe, AZ

Where to Watch:  ESPN2

DraftKings:  Point Spread:  Houston +7, ASU -7; Over/Under:  45.5 points

Bet365:  Point Spread:  Houston +7, ASU -7; Over/Under:  45.5 points

BetMGM:  Point Spread:  Houston +7, ASU -7; Over/Under:  45.5 points

Houston Cougars:  6-1 (3-1) (4th place, Big 12)

Arizona State Sun Devils:  5-2 (3-1) (5th place, Big 12)

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Houston Cougars:  won their last game at home against the Arizona Wildcats 31-28.

Arizona State Sun Devils:  won their last game at home against the Texas Tech Red Raiders 26-22.

Houston is entering this game with a 6-1 record overall and they have a 3-1 record in their conference games too. They are 3-1 in their home games, 3-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against Arizona 31-28. Conner Weigman was the starting QB and he completed 15/23 passes for 164 passing yards, 3 touchdowns, and 0 interceptions. Dean Connors led the team in rushing yards with 100. Amare Thomas led the receivers with 69 receiving yards on 4 receptions and 2 TDs. Kentrell Webb led the defense in that game with 7 solo tackles and 3 assisted tackles while Wrook Brown led the defense in sacks with 1.5. No one on the defense came away with an interception for them in that one.

 

 

 

Arizona State is entering this game with a 5-2 record overall and they have a 3-1 record in their conference games too. They are 4-0 in their home games, 1-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against Texas Tech 26-22. Sam Leavitt was the starting QB and he completed 28/47 passes for 319 passing yards, 1 touchdown, and 0 interceptions. Raleek Brown led the team in rushing yards with 69 and 1 TD. Jordyn Tyson led the receivers with 105 receiving yards on 10 receptions and 1 TD. Keyshaun Elliott led the defense in that game with 6 solo tackles and 4 assisted tackles while Anthonie Cooper and Prince Dorbah each led the defense in sacks with 1. Martell Hughes came away with the only interception for them in that one.

The current betting odds have Arizona State listed as a 7 point favorite in this game according to Draftkings Sportsbook. Arizona State has looked really good in their games this season with their 5-2 record overall and their 3-1 conference record which has them right near the top of the Big 12. They only have 1 loss in the conference and they are still the defending champions of the Big 12 so they can still make a run at the Big 12 and will be motivated to show they are still the team to beat. They looked great in their last one too, coming off a big win over Texas Tech and they are going to have a ton of momentum from that win as Texas Tech was the highest ranked team in the conference. Meanwhile, Houston has looked really good in their games this season with their 6-1 record overall and their 3-1 conference record which has them right near the top of the Big 12. Their only loss was at home against Texas Tech and they have looked great in a lot of their wins, but they got obliterated by Texas Tech at home as they weren't even in the game and now they are off a 31-28 win over Arizona at home in another game which they struggled in. They are 3-0 in road games this season, but they have also had a really weak schedule this season and this is going to be the first time they are challenged since the Texas Tech loss. Houston is good, but they aren't quite there yet and Arizona State is going to use this home game as a statement to show why they are still the team to beat in the Big 12. The best way to place a bet here is on Arizona State to cover the spread in this game. 

Houston Arizona State Prediction:  Our NCAAF Pick for Saturday, October 25, 2025 (8:00 pm ET start time) is Arizona State 34 Houston 24.

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Houston Cougars: 1-6 ATS as an underdog of 3.5 to 10 points. 1-4 ATS when playing against a good team (Win Pct. 60% to 75%). 1-5 ATS on the road off a home win. 15-6 UNDER as an underdog. 5-1 UNDER after a win by 6 or less points. 8-4 UNDER when playing against a team with a winning record.

Arizona State Sun Devils: 20-11 ATS in all lined games. 5-0 ATS as a home favorite of 7 points or less. 15-6 ATS against conference opponents. 8-3 ATS when playing against a top-level team (Win Pct. > 75%). 7-4 UNDER off a home win. 5-2 UNDER after a win by 6 or less points.

Houston Cougars:  J. Burnette (RB) Probable - Undisclosed. C. Allen Jr. (DL) Questionable - Undisclosed. Q. Lee (DL) Out - Undisclosed. L. McGary (TE) Out - Undisclosed. K. West (CB) Out - Undisclosed. S. Sneed (RB) Out - Undisclosed. J. Ridgle (RB) Out - Undisclosed. D. Williams (WR) Out - Undisclosed. S. Johnson (WR) Out - Undisclosed. K. Parks (CB) Questionable - Undisclosed. D. Ndukwe (OG) Out - Leg. R. Sanford II (RB) Out - Undisclosed.

Arizona State Sun Devils:  A. Ia (TE) Probable - Undisclosed. C. Fite (DL) Probable - Undisclosed. W. Helton (OG) Probable - Undisclosed. M. Iheanachor (OG) Probable - Undisclosed. P. Young-Blackgoat (LB) Probable - Undisclosed. K. McDonald (CB) Probable - Undisclosed. K. Floyd (P) Probable - Undisclosed. J. Bal (CB) Probable - Undisclosed. A. Fall (CB) Probable - Undisclosed. K. Anderson (TE) Probable - Undisclosed. S. Leavitt (QB) Probable - Undisclosed. C. Metayer (TE) Probable - Undisclosed. T. Romney (LB) Questionable - Undisclosed. J. Crook (LB) Questionable - Undisclosed. A. Wilson (S) Questionable - Undisclosed. M. Rowser (CB) Questionable - Undisclosed. P. Dorbah (DL) Doubtful - Undisclosed. Z. Swanson (DL) Out - Undisclosed. J. Fortier (TE) Out - Undisclosed. N. Johnson (WR) Out - Undisclosed. K. Brown (RB) Out - Undisclosed. J. Tyson (WR) Out - Hamstring. Z. Fiaseu (LB) Out - Undisclosed. X. Alford (CB) Out - Undisclosed. B. Coleman (OG) Out - Arm.

“That’s one of our goals. You want to play in a bowl game. I’ve never been to a bad one. I’ve been to a bunch of them. They’re all good. So, we’re excited about that.” - Willie Fritz after his team’s win against Arizona in their last game. 

“I’ve never been around a guy who just works to win football games as much as he does and in the biggest moments he makes the biggest plays.” - Kenny Dillingham after his team’s win against Texas Tech in their last game. 

WR Young, Koby

WR Johnson, Stephon

WR Thomas, Amare

TE Koziol, Tanner

QB Weigman, Conner

RB Connors, Dean

WR McClain, Malik

WR Tyson, Jordyn

WR Eusebio, Derek

TE Metayer, Chamon

TE Harpole, Cameron

QB Leavitt, Sam

RB Brown, Raleek 

Passing: Conner Weigman (1,380)

Rushing: Dean Connors (538)

Receiving: Amare Thomas (510)

Touchdowns: Conner Weigman (6)

Passing: Sam Leavitt (1,358)

Rushing: Raleek Brown (642)

Receiving: Jordyn Tyson (628)

Touchdowns: Jordyn Tyson (9)

Coaches:

Houston Cougars: Willie Fritz (2nd season)

Arizona State Sun Devils: Kenny Dillingham (3rd season)