Houston Astros vs New York Yankees Prediction, Preview and Odds - 08/08/2025

Game Time: 7:05 pm ET, Friday, August 8, 2025

Venue:  Yankee Stadium, Bronx, NY

Where to Watch:  Apple TV+

DraftKings:  Moneyline odds:  Astros -126, Yankees +104; Over/Under:  8 runs

Bet365:  Moneyline odds:  Astros -125, Yankees +105; Over/Under:  8 runs

BetMGM:  Moneyline odds:  Astros -130, Yankees +110; Over/Under:  8 runs

Houston Astros:  64-51 (1st place, AL West)

New York Yankees:  61-54 (3rd place, AL East)

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Houston Astros:  4-6 last 10

New York Yankees:  4-6 last 10

The Astros are entering this series off a loss and won their 3-game series against the Miami Marlins 2-1 in their last series. They enter this game with a 64-51 record overall and have a road record of 29-27. This is the series opener of a 3-game series with the Yankees on Friday and they have Thursday off as a day of rest. Their offense ranks 11th in the MLB with a .729 OPS. Spencer Arrighetti was their starting pitcher on Wednesday while Hunter Brown is making his start in this game on Friday. He is 9-5 with a 2.47 ERA this season. His team lost their last 2 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 1 ER, 0 HR, and 1 BB with 6 SO on 4 hits through 7 IP against the Boston Red Sox.

The Yankees are entering this series off a win and lost their 3-game series against the Texas Rangers 2-1 in their last series. They enter this game with a 61-54 record overall and have a home record of 34-22. This is the 1st game of a 3-game series with the Astros on Friday and they have Thursday off as a day of rest. Their offense ranks 1st in the MLB with a .776 OPS. Carlos Rodón was their starting pitcher on Wednesday while rookie pitcher Cam Schlittler is making his start in this game on Friday. He is 1-2 with a 4.58 ERA this season. His team lost their last 2 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 2 earned runs, 2 homers, and 2 walks with 6 strikeouts on 4 hits through 5 innings pitched against the Miami Marlins.

The current betting odds have the Astros listed as a slight favorite in this game according to Draftkings Sportsbook. The Astros have looked great in their games this season with their 64-51 record overall which has them right at the top of the AL West. They have been a good road team too with their 29-27 road record this season. Meanwhile, the Yankees have looked good in their games this season with their 61-54 record overall which has them right in the middle of the AL East and in the Wild Card race. They have looked great in their own ballpark though with their 34-22 home record this year. Both of these teams haven't looked great lately as both are 4-6 in their last 10 games, but the Astros always bring their best effort for the Yankees and they do have the better pitching matchup that they can take advantage of. Brown is on the mound for the Astros and he has looked great this year. He is 9-5 with a 2.47 ERA and hasn't been giving up many runs all season. His team has struggled more lately as they have lost 2 games in a row with him starting, but he only gave up 1 earned run in his last start and that has been a common theme for him. The Yankees are going with Schlittler in this one and he hasn't looked great this season. He is 1-2 with a 4.58 ERA and has been giving up quite a few runs lately. He only gave up 2 earned runs in his last start, but the team has lost 2 games in a row now with him starting and that will be an issue with the Astros offense getting hot now. The Yankees have one of the best offenses in the MLB, but they haven't been putting up a ton of runs lately so the Astros have the edge here with the better pitching. The best way to place a bet here is on the Astros to win this game. 

Astros Yankees Prediction:  Our MLB Pick for Friday, August 8, 2025 (7:05 pm ET start time) is Astros 6 Yankees 4.

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Houston Astros: 249-201 (-9.1 units) on the moneyline in all games. 168-139 (-41.3 units) on the moneyline as a favorite of -110 or higher. 149-128 (-23.3 units) on the moneyline vs. an AL team with an on base percentage .330 or worse. 45-27 OVER vs. AL teams scoring 4.9 or more runs/game on the season.

New York Yankees: 57-33 (+10.2 units) on the moneyline against AL West opponents. 53-54 (+10.8 units) on the moneyline as an underdog of +100 or higher. 122-77 (+9.3 units) on the moneyline vs. an AL team with a slugging percentage .410 or worse on the season. 30-18 OVER at home when the money line is +125 to -125.

Houston Astros:  I. Paredes (3B) Sixty Day IL - Hamstring. B. Walter (RP) Fifteen Day IL - Elbow. L. McCullers Jr. (SP) Fifteen Day IL - Finger. B. Rodgers (2B) Sixty Day IL - Oblique. J. Meyers (CF) Ten Day IL - Calf. Z. Dezenzo (RF) Sixty Day IL - Hand. Y. Alvarez (LF) Sixty Day IL - Hand. S. Dubin (RP) Fifteen Day IL - Forearm. P. Leon (RF) Sixty Day IL - Knee. R. Blanco (SP) Sixty Day IL - Elbow. H. Wesneski (RP) Sixty Day IL - Elbow. L. Garcia (SP) Sixty Day IL - Elbow. C. Javier (SP) Sixty Day IL - Elbow. J. France (SP) Sixty Day IL - Shoulder.

New York Yankees:  A. Slater (LF) Ten Day IL - Hamstring. J. Loaisiga (RP) Fifteen Day IL - Back. C. Schmidt (SP) Sixty Day IL - Forearm. F. Cruz (RP) Fifteen Day IL - Oblique. R. Yarbrough (SP) Fifteen Day IL - Oblique. O. Cabrera (3B) Sixty Day IL - Ankle. J. Cousins (RP) Sixty Day IL - Elbow. G. Cole (SP) Sixty Day IL - Elbow.

“I thought he kind of missed some pitches out over the plate. A combination of that and some soft contact also. A little rusty there, but stuff-wise, I thought he was spinning the ball well. The shape of his pitches was pretty good.” - Joe Espada on Spencer Arrighetti after his team’s loss against the Marlins in their game on Wednesday.

“What a great, gutsy effort.” - Aaron Boone after his team’s win against the Rangers in their game on Wednesday.

Carlos Correa (R) 3B

Jesús Sánchez (L) LF

Jose Altuve (R) 2B

Christian Walker (R) 1B

Victor Caratini (S) C

Yainer Diaz (R) DH

Taylor Trammell (L) CF

Cam Smith (R) RF

Mauricio Dubón (R) SS

Trent Grisham (L) CF

Ben Rice (L) 1B

Aaron Judge (R) DH

Cody Bellinger (L) RF

Jazz Chisholm Jr. (L) 2B

Jasson Domínguez (S) LF

Anthony Volpe (R) SS

Ryan McMahon (L) 3B

Austin Wells (L) C

Batting Average:  Carlos Correa (.346)

Hits:  Jose Altuve (120)

Home Runs:  Isaac Paredes (19)

RBI:  Christian Walker (61)

Stolen Bases:  Jeremy Peña (15)

Wins:  Framber Valdez (11)

Saves:  Josh Hader (28)

ERA:  Shawn Dubin (1.33)

Batting Average:  Amed Rosario (.600)

Hits:  Aaron Judge (130)

Home Runs:  Aaron Judge (37)

RBI:  Aaron Judge (85)

Stolen Bases:  Jasson Domínguez (19)

Wins:  Max Fried (12)

Saves:  Devin Williams (17)

ERA:  Adam Ottavino (0.00)

Managers:

Houston Astros: Joe Espada (2nd season)

New York Yankees: Aaron Boone (8th season)