Houston Astros vs Detroit Tigers Prediction, Preview and Odds - 08/19/2025

Game Time: 6:40 pm ET, Tuesday, August 19, 2025

Venue:  Comerica Park, Detroit, MI

Where to Watch:  TBS

DraftKings:  Moneyline odds:  Astros +140, Tigers -172; Over/Under:  7 runs

Bet365:  Moneyline odds:  Astros +140, Tigers -170; Over/Under:  7 runs

BetMGM:  Moneyline odds:  Astros +140, Tigers -170; Over/Under:  7 runs

Houston Astros:  69-55 (1st place, AL West)

Detroit Tigers:  73-53 (1st place, AL Central)

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Houston Astros:  5-5 last 10

Detroit Tigers:  7-3 last 10

The Astros are entering this series off a loss and lost their 3-game series against the Baltimore Orioles 2-1 in their last series. They enter this game with a 69-55 record overall and have a road record of 31-28. This is the 2nd game of a 3-game series with the Tigers on Tuesday with the series opener still to be played on Monday. Their offense ranks 13th in the MLB with a .722 OPS. Spencer Arrighetti is their starting pitcher on Monday while Hunter Brown is making his start in this game on Tuesday. He is 10-5 with a 2.45 ERA this season. His team won their last 2 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 1 ER, 0 HR, and 3 BB with 4 SO on 6 hits through 6.2 IP against the Boston Red Sox.

The Tigers are entering this series off a loss and won their 4-game series against the Minnesota Twins 3-1 in their last series. They enter this game with a 73-53 record overall and have a home record of 39-24. This is the 2nd game of a 3-game series with the Astros on Tuesday with the 1st game of this series still to be played on Monday. Their offense ranks 10th in the MLB with a .736 OPS. Jack Flaherty is their starting pitcher on Monday while Tarik Skubal is making his start in this game on Tuesday. He is 11-3 with a 2.42 ERA this season. His team won their last 3 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 3 earned runs, 1 homer, and 2 walks with 3 strikeouts on 6 hits through 7 innings pitched against the Minnesota Twins.

The current betting odds have the Tigers listed as a favorite in this game according to Draftkings Sportsbook. The Tigers have looked great in their games this season with their 73-53 record overall which has them right at the top of the AL Central. They have also looked great in their own ballpark this year with their 39-24 home record. Meanwhile, the Astros have looked great in their games this season with their 69-55 record overall which has them right at the top of the AL West. They have been a good road team too with their 31-28 road record this season. The Astros haven't looked great lately though, going 5-5 in their last 10 games and coming off a series loss to the Orioles. The Tigers are coming off a series win though and they have been rolling lately, going 7-3 in their last 10 games. The Tigers are going with Skubal in this one and he has looked great this season. He is 11-3 with a 2.42 ERA and he has been their best starter all year. He did give up 3 earned runs in his last start, but that hasn't been a common theme for him this year so he will bounce back at home with a better start and the team has still won 3 games in a row now with him starting too. The Astros are going with Brown in this one and he has looked great this season. He is 10-5 with a 2.45 ERA and hasn't been giving up many runs either. He is coming off a great start in which he gave up 1 earned run and the team has won 2 games in a row now with him starting too. The Astros haven't looked great lately though as their offense has been really up and down and runs aren't going to come easily in this one. The Tigers have also been putting up a ton of runs this year and they have the better bullpen to edge the Astros out in this one. The best way to place a bet here is on the Tigers to win this game. 

Astros Tigers Prediction:  Our MLB Pick for Tuesday, August 19, 2025 (6:40 pm ET start time) is Tigers 2 Astros 0.

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Houston Astros: 50-43 (-12.9 units) on the moneyline against AL Central opponents. 254-205 (-8 units) on the moneyline in all games. 70-52 (-6.1 units) on the moneyline against left-handed starters. 11-6 OVER when playing against a team with a winning record in the second half of the season.

Detroit Tigers: 241-217 (+31.3 units) on the moneyline in all games. 119-71 (+15 units) on the moneyline as a favorite of -110 or higher. 182-168 (+18.7 units) on the moneyline against right-handed starters. 11-6 OVER at home when the total is 7 or less.

Houston Astros:  C. Javier (SP) Day To Day - Illness. J. Hader (RP) Fifteen Day IL - Shoulder. I. Paredes (3B) Sixty Day IL - Hamstring. B. Walter (RP) Fifteen Day IL - Elbow. L. McCullers Jr. (SP) Ten Day IL - Finger. B. Rodgers (2B) Sixty Day IL - Oblique. J. Meyers (CF) Ten Day IL - Calf. Z. Dezenzo (RF) Sixty Day IL - Hand. Y. Alvarez (LF) Sixty Day IL - Hand. P. Leon (RF) Sixty Day IL - Knee. R. Blanco (SP) Sixty Day IL - Elbow. H. Wesneski (RP) Sixty Day IL - Elbow. L. Garcia (SP) Sixty Day IL - Elbow. J. France (SP) Sixty Day IL - Shoulder.

Detroit Tigers:  M. Vierling (CF) Ten Day IL - Oblique. P. Sewald (RP) Sixty Day IL - Shoulder. R. Olson (SP) Sixty Day IL - Shoulder. P. Meadows (CF) Ten Day IL - Quad. S. Guenther (RP) Sixty Day IL - Hip. J. Jobe (SP) Sixty Day IL - Flexor. J. Foley (RP) Sixty Day IL - Shoulder. A. Cobb (SP) Sixty Day IL - Hip. T. Madden (SP) Sixty Day IL - Shoulder. J. Urquidy (SP) Sixty Day IL - Elbow. A. Lange (RP) Sixty Day IL - Lat.

“Trying to make him just shorter through the ball and kind of elevate some of those [pitches]. Right now he’s kind of … beating the ball in the ground. He’s getting good pitches to hit and has just got to make that tiny adjustment.” - Joe Espada after his team’s loss against the Orioles in their game on Sunday.

“We feel good. We’re playing well. You try to win every game, but you know it’s not going to happen. But you come out of this winning a four-game series in the first three games. Wash this one off, go home, play a good Houston team.” - A.J. Hinch after his team’s loss against the Twins in their game on Sunday.

Jeremy Peña (R) SS

Carlos Correa (R) 3B

Jose Altuve (R) 2B

Jesús Sánchez (L) RF

Yainer Diaz (R) DH

Victor Caratini (S) C

Mauricio Dubón (R) 1B

Jacob Melton (L) CF

Taylor Trammell (L) LF

Colt Keith (L) 3B

Kerry Carpenter (L) DH

Spencer Torkelson (R) 1B

Riley Greene (L) LF

Wenceel Pérez (S) RF

Javier Báez (R) CF

Zach McKinstry (L) 2B

Trey Sweeney (L) SS

Jake Rogers (R) C

Batting Average:  Carlos Correa (.339)

Hits:  Jose Altuve (129)

Home Runs:  Jose Altuve (22)

RBI:  Christian Walker (65)

Stolen Bases:  Jeremy Peña (17)

Wins:  Framber Valdez (11)

Saves:  Josh Hader (28)

ERA:  Enyel De Los Santos (0.00)

Batting Average:  Brewer Hicklen (.667)

Hits:  Riley Greene (125)

Home Runs:  Riley Greene (28)

RBI:  Riley Greene (90)

Stolen Bases:  Zach McKinstry (19)

Wins:  Casey Mize (12)

Saves:  Will Vest (18)

ERA:  Kyle Finnegan (0.00)

Managers:

Houston Astros: Joe Espada (2nd season)

Detroit Tigers: A.J. Hinch (5th season)