Green Bay Packers vs Pittsburgh Steelers Prediction, Preview and Odds - 10/26/2025

Game Time: 8:20 pm ET, Sunday, October 26, 2025

Venue:  Acrisure Stadium, Pittsburgh, PA 

Where to Watch:  NBC

DraftKings:  Point Spread:  Packers -3, Steelers +3; Over/Under:  45.5 points

Bet365:  Point Spread:  Packers -3, Steelers +3; Over/Under:  45.5 points

BetMGM:  Point Spread:  Packers -3, Steelers +3; Over/Under:  45.5 points

Green Bay Packers:  4-1-1 (1st place, NFC North)

Pittsburgh Steelers:  4-2 (1st place, AFC North)

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Green Bay Packers:  won their last game on the road against the Arizona Cardinals 27-23.

Pittsburgh Steelers:  lost their last game on the road against the Cincinnati Bengals 33-31.

The Packers are entering this game with a 4-1-1 record overall and they have a 1-0 record in their divisional games too. They are 3-0 in their home games, 1-1-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against the Arizona Cardinals 27-23. Jordan Love was the starting QB and he completed 19/29 passes for 179 passing yards, 1 touchdown, and 0 interceptions. Josh Jacobs led the team in rushing yards with 55 and 2 TDs. Romeo Doubs led the receivers with 72 receiving yards on 6 receptions. Quay Walker led the defense in that game with 5 solo tackles and 4 assisted tackles while Micah Parsons led the defense in sacks with 3. No one on the defense came away with an interception for them in that one.

 

 

 

The Steelers are entering this game with a 4-2 record overall and they have a 1-1 record in their divisional games too. They are 1-1 in their home games, 2-1 in their road games, and they are also 1-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against the Cincinnati Bengals 33-31. Aaron Rodgers was the starting QB and he completed 23/34 passes for 249 passing yards, 4 touchdowns, and 2 interceptions. Jaylen Warren led the team in rushing yards with 127. Pat Freiermuth led the receivers with 111 receiving yards on 5 receptions and 2 TDs. DeShon Elliott led the defense in that game with 6 solo tackles and 3 assisted tackles while Keeanu Benton led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.

The current betting odds have the Packers listed as a 3 point favorite in this game according to Draftkings Sportsbook. The Packers have looked great in their games this season with their 4-1-1 record overall which has them right at the top of the NFC North with one of the best records in the entire NFL. They are off a 27-23 win over the Cardinals in their last one and they did need a bit of a late comeback to win that one, but their defense has looked great this season and really stepped up against the Cardinals when they needed to make plays to win the game. Meanwhile, the Steelers have looked good in their games this season with their 4-2 record overall which has them right at the top of the AFC North. They have been really up and down this season though and they are off a 33-31 loss to the Bengals in their last one. The defense has always been the strength of this Steelers team, but their defense hasn't looked good this season. They have been giving up a ton of points in their games and just let Joe Flacco carve them up in his 2nd game in that offense. The Steelers have looked great on offense this year with Rodgers playing great, but they don't really have a good run game either. This Packers offense has been really balanced all season and their defense has looked a lot better too, and that should give them the edge in this one. The best way to place a bet here is on the Packers to cover the spread in this game. 

Packers Steelers Prediction:  Our NFL Pick for Sunday, October 26, 2025 (8:20 pm ET start time) is Packers 24 Steelers 16.

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Green Bay Packers: 2-7 ATS as a road favorite. 3-7 ATS in a road game where the total is between 42.5 and 49 points. 2-10 ATS vs. poor passing defenses - allowing 235 or more passing yards/game. 7-4 UNDER in non-conference games.

Pittsburgh Steelers: 17-9 ATS in games where the line is +3 to -3. 5-1 ATS after scoring 30 points or more last game. 4-1 ATS vs. good passing defenses - allowing 5.7 or less passing yards/att. 5-0 UNDER in a home game where the total is between 42.5 and 49 points. 4-1 UNDER when playing against a top-level team (Win Pct. > 75%).

Green Bay Packers:  B. McManus (K) Injured - Quadricep. J. Jacobs (RB) Injured - Calf. X. McKinney (S) Injured - Ankle. N. Hobbs (CB) Injured - Knee. A. Banks (OG) Injured - Groin. Z. Tom (OG) Injured - Back. Q. Walker (LB) Injured - Neck. D. Wyatt (DL) Injured - Knee. D. Wicks (WR) Injured - Calf. L. Van Ness (DL) Injured - Foot. C. Watson (WR) Injured - Knee. E. Williams (S) Injured - Back. J. Morgan (OT) Injured - Knee. A. Belton (OT) Injured - Ankle.

Pittsburgh Steelers:  S. Miller (WR) Injured - Finger. D. Metcalf (WR) Injured - Rest. C. Heyward (DL) Injured - Rest. T. Watt (LB) Injured - Rest. C. Austin III (WR) Injured - Shoulder. M. Harrison (LB) Injured - Knee. Z. Frazier (C) Injured - Calf. W. Howard (QB) Injured - Hand.

“From the moment we got on the trip, nothing seemed to go right. Then in-game, there were a lot of things that didn't go right. But the guys kept battling and that's what it takes in this league.” - Matt LaFleur after his team’s win against the Cardinals in their last game. 

“I just thought the first half we allowed them to run the ball too much. Then we turned the ball over a couple of times, and that just kind of set a negative trajectory. We’re fighting uphill the rest of the way.” - Mike Tomlin after his team’s loss against the Bengals in their last game. 

WR Doubs, Romeo

WR Heath, Malik

WR Golden, Matthew

TE Kraft, Tucker

QB Love, Jordan

RB Jacobs, Josh

WR Metcalf, DK

WR Austin III, Calvin

TE Smith, Jonnu

TE Washington, Darnell

QB Rodgers, Aaron

RB Warren, Jaylen

Passing: Jordan Love (1,438)

Rushing: Josh Jacobs (414)

Receiving: Tucker Kraft (326)

Touchdowns: Josh Jacobs (8)

Passing: Aaron Rodgers (1,270)

Rushing: Jaylen Warren (311)

Receiving: DK Metcalf (406)

Touchdowns: DK Metcalf (4)

Coaches:

Green Bay Packers: Matt LaFleur (7th season)

Pittsburgh Steelers: Mike Tomlin (19th season)