Florida International Panthers vs Penn State Nittany Lions Prediction, Picks and Game Preview - 09/06/2025

Game Time: 12:00 pm ET, Saturday, September 6, 2025

Venue:  Beaver Stadium, University Park, PA

Where to Watch:  Big Ten Network

DraftKings:  Point Spread:  FIU +41.5, PSU -41.5; Over/Under:  53.5 points

Bet365:  Point Spread:  FIU +41.5, PSU -41.5; Over/Under:  54.5 points

BetMGM:  Point Spread:  FIU +41.5, PSU -41.5; Over/Under:  54.5 points

Florida International Panthers:  1-0 (0-0) (2nd place, CUSA)

Penn State Nittany Lions:  1-0 (0-0) (4th place, Big Ten)

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Florida International Panthers:  won their last game at home against the Bethune-Cookman Wildcats 42-9.

Penn State Nittany Lions:  won their last game at home against the Nevada Wolf Pack 46-11.

FIU is entering this game with a 1-0 record overall and they have a 0-0 record in their conference games too. They are 1-0 in their home games, 0-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against Bethune-Cookman 42-9. Keyone Jenkins was the starting QB and he completed 18/30 passes for 187 passing yards, 0 touchdowns, and 0 interceptions. Kejon Owens led the team in rushing yards with 71 and 2 TDs. Eric Nelson led the receivers with 47 receiving yards on 2 receptions. Johnny Chaney Jr. led the defense in that game with 6 solo tackles and 2 assisted tackles while Percy Courtney Jr. and Kenton Simmons each led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.

 

 

 

Penn State is entering this game with a 1-0 record overall and they have a 0-0 record in their conference games too. They are 1-0 in their home games, 0-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against Nevada 46-11. Drew Allar was the starting QB and he completed 22/26 passes for 217 passing yards, 1 touchdown, and 0 interceptions. Kaytron Allen led the team in rushing yards with 43 and 1 TD. Kyron Hudson led the receivers with 89 receiving yards on 6 receptions and 1 TD. Dani Dennis-Sutton led the defense in that game with 4 solo tackles and 1 assisted tackle while Dani Dennis-Sutton, Dejuan Lane, and Dominic Deluca each led the defense in sacks with 1. Zane Durant came away with the only interception for them in that one.

The current betting odds have FIU listed as a 41.5 point underdog in this game according to Draftkings Sportsbook. FIU is 1-0 overall and looked good in their season opener. They won 42-9 and were playing against a team from the FCS so they weren't really challenged in that one, but they did put up some offense which hasn't been a common theme for them over the years. Willie Simmons is in his 1st year coaching this team and the offense has already looked a lot better than previous years. Penn State does have one of the best defenses in the nation and they have a lot more talent that this FIU team, but they did give up 11 points at home to a terrible Nevada team in week 1 so FIU can definitely put up some points here, especially in garbage time. Penn State is 1-0 overall this season and looked great in their season opener, but they still only put up 46 points at home against a bad Nevada defense. They didn't need to do much once they got out to a big lead, but they still failed to cover the spread in that game and they are going to be another favorite in this one by over 40 points. This is a really big number for a Penn State team that doesn't need to play a full 60 minutes to win this game so look for FIU to do just enough to keep this game within the number. The best way to place a bet here is on FIU to cover the spread in this game. 

Florida International Penn State Prediction:  Our NCAAF Pick for Saturday, September 6, 2025 (12:00 pm ET start time) is Penn State 52 FIU 13.

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Florida International Panthers: 2-5 ATS against Big 10 conference opponents. 1-3 ATS as a road underdog of 35.5 to 42 points. 6-3 OVER in road lined games. 9-2 1H OVER when the total is between 49.5 and 56.

Penn State Nittany Lions: 17-9 ATS as a favorite. 9-5 ATS as a home favorite. 6-3 ATS off a home win by 17 points or more. 9-2 OVER when the total is between 49.5 and 56. 4-1 OVER as a favorite of 31 or more points.

Florida International Panthers:  None.

Penn State Nittany Lions:  J. Mayer (DL) Questionable - Undisclosed. P. Gonzalez (WR) Questionable - Undisclosed. D. Nastasi (CB) Questionable - Undisclosed. E. Boyer (OG) Questionable - Undisclosed. L. Horan (OG) Questionable - Undisclosed. B. O'Hara (OG) Questionable - Undisclosed. K. Artis (DL) Questionable - Undisclosed. Z. Fisher (DL) Questionable - Undisclosed. M. Robinson (DL) Questionable - Undisclosed. M. Granville (DL) Questionable - Undisclosed. B. Kritza (QB) Questionable - Undisclosed. J. Brown (WR) Questionable - Undisclosed. Z. Tracy (CB) Questionable - Undisclosed. K. Saunders (WR) Out - Undisclosed.

“Building depth is the only way to survive in today’s (transfer-portal) climate. We may not get the star power (FIU) had in the past with guys like (wide receiver) T.Y. Hilton or (safety) Jonathan Cyprien. But if you have a deep roster, one major (transfer) loss like (wide receiver) Eric Rivers (to Georgia Tech) or (linebacker) Travion Barnes (to Baylor) doesn’t kill your program.” - Willie Simmons after his team’s win against BCU in their last game. 

“You see a ton of sloppy football early in the season. I didn’t see any of that. We didn’t have stupid penalties. We didn’t put the ball on the ground. We didn’t turn it over. We didn’t burn timeouts. That was big.” - James Franklin after his team’s win against Nevada in their last game. 

WR Hudson, Kyron

WR Ross, Devonte

WR Peña, Trebor

TE Dinkins, Khalil

QB Allar, Drew

RB Singleton, Nicholas

WR Hudson, Kyron 

WR Ross, Devonte

WR Peña, Trebor 

TE Dinkins, Khalil 

QB Allar, Drew

RB Singleton, Nicholas

Passing: K. Jenkins (187)

Rushing: K. Owens (71)

Receiving: E. Nelson (47)

Touchdowns: K. Jenkins (2)

Passing: D. Allar (217)

Rushing: K. Allen (43)

Receiving: K. Hudson (89)

Touchdowns: N. Singleton (2)

Coaches:

Florida International Panthers: Willie Simmons (1st season)

Penn State Nittany Lions: James Franklin (12th season)