Detroit Pistons vs New York Knicks Prediction, Preview and Odds - 10/27/2026

Game Time: 8:00 pm ET, Tuesday, October 27, 2026

Venue:  Madison Square Garden, New York, NY 

Where to Watch:  NBC

DraftKings:  Point Spread:  Pistons +4.5, Knicks -4.5; Over/Under:  219 points

Bet365:  Point Spread:  Pistons +4.5, Knicks -4.5; Over/Under:  219 points

BetMGM:  Point Spread:  Pistons +4.5, Knicks -4.5; Over/Under:  219 points

Detroit Pistons:  3-0 (1st place, Central Division)

New York Knicks:  0-3 (4th place, Atlantic Division)

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Detroit Pistons:  3-0 last 3

New York Knicks:  0-3 last 3

The Pistons are entering this game with a 3-0 record overall this season and they are 2-0 in their road games this season where they will be in this game. They are entering this game on a 3 game winning streak with wins coming against the Boston Celtics, the Miami Heat, and the Philadelphia 76ers. Cade Cunningham led the team in points in that game with 26 while Duncan Robinson was next on the team with 21 points. Cade Cunningham led the team in assists in that game with 8 while John Collins led the team in rebounds with 11. They were 43.7% from the field, 41.2% from 3-point range, and 64% from the free throw line with their shots in that game. Their offense is averaging 118.3 PPG and their defense is allowing their opponents to average 105.7 PPG against them. The Pistons have an ATS record of 3-0 this season and their O/U record is 2-1.

The Knicks are entering this game with a 0-3 record overall this season and they are 0-2 in their home games this season where they will be in this game. They are entering this game on a 3 game losing streak with losses coming against the Philadelphia 76ers, the Boston Celtics, and the Orlando Magic. Jalen Brunson led the team in points in that game with 28 while OG Anunoby and Karl-Anthony Towns each were next on the team with 22 points. Tyler Kolek led the team in assists in that game with 9 while Karl-Anthony Towns led the team in rebounds with 14. They were 40.9% from the field, 23.7% from 3-point range, and 70.8% from the free throw line with their shots in that game. Their offense is averaging 101.7 PPG and their defense is allowing their opponents to average 108 PPG against them. The Knicks have an ATS record of 0-3 this season and their O/U record is 0-3.

The current betting odds have the Pistons listed as a 4.5 point underdog in this game according to Draftkings Sportsbook. The Pistons have looked great in their games this season with their 3-0 record overall which has them right at the top of the East. They have been a good road team too with their 2-0 road record this year. Meanwhile, the Knicks have looked terrible in their games this season with their 0-3 record overall which has them right near the bottom of the East. They have looked terrible on their home court too with their 0-2 road record this year. The Knicks are the defending NBA champions, but that hangover has been with them to start this season. They have lost some really tight games this season, but now they are coming off a terrible loss to the banged up Magic and still find themselves winless. They haven't looked ready to start this season and now they aren't going to have it any easier in this game. The Pistons were the best team in the East in the regular season last year and they have started the season strong again. They are coming off a win over the red hot 76ers in their last one and they have been rolling with 3 wins in a row. They have been a great defensive team too and they are going to bring their best effort for the defending champions, especially since the Knicks haven't been at their best. The Pistons have the talent to win this game outright with their hot start to the year, but they can also keep this game tight in a loss. The best way to place a bet here is on the Pistons to cover the spread in this game. 

Pistons Knicks Prediction:  Our NBA Pick for Tuesday, October 27, 2026 (8:00 pm ET start time) is Pistons 108 Knicks 105.

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Detroit Pistons: 31-13 ATS against Atlantic division opponents. 9-5 ATS versus poor 3 point shooting teams - making 33% of their attempts or less. 33-22 ATS versus poor teams - outscored by their opponents by 3+ points/game. 16-10 OVER after successfully covering the spread in 3 or more consecutive games. 22-14 OVER versus poor pressure defensive teams - forcing 13 turnovers/game or less. 

New York Knicks: 22-28 ATS against Central division opponents. 3-7 ATS off an upset loss as a home favorite. 5-8 ATS after 2 or more consecutive losses. 28-21 OVER against Central division opponents. 23-17 OVER versus poor pressure defensive teams - forcing 13 turnovers/game or less. 

Detroit Pistons:  J. Duren (C) Out - Hamstring. A. Thompson (SF) Day To Day - Ankle.

New York Knicks:  None.

"It don't matter. We're going to keep on going and let whatever people that are talking about us say whatever they want to say about us." - Cade Cunningham after their win against the 76ers in their game on Sunday. 

"The biggest thing is to continue to coach them or tell them the truth. When we play well, as I told them just now, we were great in transition in the second half. If we're trying the right way, sometimes you go to fight through stuff like this to get back on track." - Mike Brown after his team’s loss against the Magic in their game on Sunday.  

PG Cade Cunningham

SG Duncan Robinson

SF Ausar Thompson

PF John Collins

C Jalen Duren

PG Jalen Brunson

SG Josh Hart

SF Mikal Bridges

PF OG Anunoby

C Karl-Anthony Towns

PPG: Cade Cunningham (21.3)

APG: Cade Cunningham (8)

Reb/G: Paul Reed (8.3)

PPG: Jalen Brunson (22.7)

APG: Jalen Brunson (3.7)

Reb/G: Karl-Anthony Towns (12)

Coaches:

Detroit Pistons: J.B. Bickerstaff (3rd season)

New York Knicks: Mike Brown (2nd season)