Dallas Cowboys vs Indianapolis Colts Prediction, Preview and Odds - 11/08/2026

Game Time: 1:00 pm ET, Sunday, November 8, 2026

Venue:  Lucas Oil Stadium, Indianapolis, IN

Where to Watch:  FOX

DraftKings:  Point Spread:  Cowboys -6, Colts +6; Over/Under:  51.5 points

Bet365:  Point Spread:  Cowboys -6, Colts +6; Over/Under:  51.5 points

BetMGM:  Point Spread:  Cowboys -6, Colts +6; Over/Under:  51.5 points

Dallas Cowboys:  3-5 (2nd place, NFC East)

Indianapolis Colts:  2-6 (3rd place, AFC South)

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Dallas Cowboys:  lost their last game at home against the Arizona Cardinals 33-30 in overtime. 

Indianapolis Colts:  lost their last game on the road against the Jacksonville Jaguars 42-7.

The Cowboys are entering this game with a 3-5 record overall and they have a 2-1 record in their divisional games too. They are 1-2 in their home games, 2-2 in their road games, and they are also 0-1 in their neutral site games this season, but they will be on the road for this game. They lost their last game against the Arizona Cardinals 33-30 in OT. Dak Prescott was the starting QB and he completed 19/29 passes for 195 passing yards, 1 touchdown, and 0 interceptions. Javonte Williams led the team in rushing yards with 56. CeeDee Lamb led the receivers with 58 receiving yards on 7 receptions. Shemar James led the defense in that game with 9 solo tackles while Quinnen Williams led the defense in sacks with 2. Shemar James came away with the only interception for them in that one.

 

 

 

The Colts are entering this game with a 2-6 record overall and they have a 1-2 record in their divisional games too. They are 1-2 in their home games, 0-4 in their road games, and they are also 1-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against the Jacksonville Jaguars 42-7. Daniel Jones was the starting QB and he completed 19/28 passes for 144 passing yards, 1 touchdown, and 2 interceptions. DJ Giddens led the team in rushing yards with 43. Keenan Allen led the receivers with 67 receiving yards on 7 receptions. CJ Allen led the defense in that game with 10 solo tackles while CJ Allen, J.T. Tuimoloau, and Laiatu Latu each led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.

The current betting odds have the Cowboys listed as a 6 point favorite in this game according to Draftkings Sportsbook. The Cowboys haven't looked good in their games this season with their 3-5 record overall, but that record has them right near the top of the NFC East. They haven't been a great road team though with their 2-2 road record this year. Meanwhile, the Colts have looked terrible in their games this season with their 2-6 record overall which has them right near the bottom of the AFC South. They haven't looked good on their home field either with their 1-2 home record this season. The Colts are coming off a 42-7 loss to the Jaguars in their last one and they have become a fire sale. They had one of the worst defenses in the NFL to start the season and any talent that they had left they have traded away now. They still have Taylor on the roster, but he could be the next player to go and the offense hasn't really been doing much even when he is at his best. This has quickly turned into a disaster season for the Colts and they really don't have much hope going forward this season. The Cowboys haven't looked great either and they have severely underperformed with the talent they have. They are coming off a 33-30 loss at home to the Cardinals who are one of the worst teams in the NFL and that was a big chance for them to get back to .500 and get back into the division race. Their offense did look a lot better though and they do have the talent to be one of the best offenses in the NFL. Their defense is still a big issue, but it has improved from last season and considering where the Colts are at right now, this is a game that the Cowboys simply can't lose if they still want a chance to make the playoffs. The best way to place a bet here is on the Cowboys to cover the spread in this game. 

Cowboys Colts Prediction:  Our NFL Pick for Sunday, November 8, 2026 (1:00 pm ET start time) is Cowboys 35 Colts 14.

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Dallas Cowboys: 5-11 ATS as a favorite. 3-12 ATS in all games where the total is greater than or equal to 49.5. 5-10 ATS after playing a game at home. 13-4 OVER as a favorite. 7-1 OVER vs. poor teams - outscored by 6+ points per game on the season. 

Indianapolis Colts: 7-1 ATS after a game with a turnover margin of -2 or worse. 20-14 ATS at home as an underdog of 3.5 to 9.5 points. 34-27 ATS at home vs. good offensive teams - scoring 24 or more points/game. 6-3 OVER as a home underdog. 10-4 OVER when playing against a team with a losing record. 

Dallas Cowboys:  None.

Indianapolis Colts:  None.

“What I told the guys is we obviously have to learn to finish in all three phases. We had a chance to do it in a lot of different ways. When you have people down, you have to finish them and that’s the most disappointing thing.” - Brian Schottenheimer after his team’s loss against the Cardinals in their last game. 

“It’s embarrassing. It's a butt whooping. Went down there and they kicked our teeth in. That was an old-fashioned butt whooping. That’s what’s going to show up on the film.” - Jonathan Taylor after their loss against the Jags in their last game. 

WR Pickens, George

WR Lamb, CeeDee

WR Flournoy, Ryan

TE Ferguson, Jake

QB Prescott, Dak

RB Williams, Javonte

FB Luepke, Hunter

WR Treadwell, Laquon

WR Allen, Keenan

WR Downs, Josh

TE Warren, Tyler

QB Jones, Daniel

RB Taylor, Jonathan

Passing: Dak Prescott (2,046)

Rushing: Javonte Williams (528)

Receiving: CeeDee Lamb (709)

Touchdowns: Javonte Williams (9)

Passing: Daniel Jones (1,542)

Rushing: Jonathan Taylor (610)

Receiving: Josh Downs (330)

Touchdowns: Jonathan Taylor (8)

Coaches:

Dallas Cowboys: Brian Schottenheimer (2nd season)

Indianapolis Colts: Shane Steichen (4th season)