Cleveland Cavaliers vs Detroit Pistons Prediction, Preview and Odds - 05/13/2026

Game Time: 8:00 pm ET, Wednesday, May 13, 2026

Venue:  Little Caesars Arena, Detroit, MI 

Where to Watch:  ESPN

DraftKings:  Point Spread:  Cavaliers +3.5, Pistons -3.5; Over/Under:  212.5 points

Bet365:  Point Spread:  Cavaliers +3.5, Pistons -3.5; Over/Under:  212.5 points

BetMGM:  Point Spread:  Cavaliers +4.5, Pistons -4.5; Over/Under:  212.5 points

Cleveland Cavaliers:  52-30 (2nd place, Central Division)

Detroit Pistons:  60-22 (1st place, Central Division)

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Cleveland Cavaliers:  5-5 last 10

Detroit Pistons:  6-4 last 10

The Cavaliers are entering the playoffs with a 52-30 record overall this season and they were 25-16 in their road games where they will be in this game. They are entering this game on a 2 game winning streak with wins coming against the Detroit Pistons twice in a row. Donovan Mitchell led the team in points in that game with 43 while James Harden was next on the team with 24 points. James Harden led the team in assists in that game with 11 while Evan Mobley led the team in rebounds with 8. They were 43.6% from the field, 34.1% from 3-point range, and 88.2% from the free throw line with their shots in that game. Their offense is averaging 119.5 PPG and their defense is allowing their opponents to average 115.4 PPG against them. The Cavaliers have an ATS record of 38-55 this season and their O/U record is 47-46.

The Pistons are entering the playoffs with a 60-22 record overall this season and they were 31-9 in their home games where they will be in this game. They are entering this game on a 2 game losing streak with losses coming against the Cleveland Cavaliers twice in a row. Caris LeVert led the team in points in that game with 24 while Cade Cunningham was next on the team with 19 points. Cade Cunningham led the team in assists in that game with 6 while Tobias Harris led the team in rebounds with 8. They were 50.6% from the field, 43.5% from 3-point range, and 75% from the free throw line with their shots in that game. Their offense is averaging 117.8 PPG and their defense is allowing their opponents to average 109.6 PPG against them. The Pistons have an ATS record of 49-44 this season and their O/U record is 43-49-1.

The current betting odds have the Pistons listed as a 3.5 point favorite in this game according to Draftkings Sportsbook. The Pistons have looked great in their games this season with their 60-22 record overall which had them right at the top of the East with one of the best records in the entire NBA. They have looked great on their home court too with their 31-9 home record this season. Meanwhile, the Cavaliers have looked good in their games this season with their 52-30 record overall which had them in the top half of the East. They have been a good road team too with their 25-16 road record this year. This is game 5 of a 7-game series between the 1 seeded Pistons and the 4 seeded Cavaliers in the East for the 2nd round of the NBA playoffs. This series is all evened up 2-2 after the Cavaliers won game 4 by a score of 112-103. The Cavaliers had a lot of trouble to start this series, but they bounced back at home with 2 wins in a row now. They looked a lot better in those games, but that has been the case for them all playoffs too. They needed 7 games to beat a mediocre Raptors team in the last round and they lost all 3 of their road games in that series. Now they are going back to Detroit with the series tied, but they haven't led once in this series and they still haven't won a road game in the playoffs this year. The Pistons finally lost after winning 5 games in a row, coming back down 3-1 in the last round and crushing their opponents in those 5 games, but they will be looking to bounce back at home where they have looked a lot better this season. Their defense has been really good in all of their playoff games and that is going to have a big impact here since the Cavaliers have had a lot more trouble on the offensive end in their road games. This Cavaliers team still hasn't shown that they can win on the road in the playoffs, so look for the Pistons to bounce back and take a series lead once again. The best way to place a bet here is on the Pistons to cover the spread in this game. 

Cavaliers Pistons Prediction:  Our NBA Pick for Wednesday, May 13, 2026 (8:00 pm ET start time) is Pistons 110 Cavaliers 104.

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Cleveland Cavaliers: 16-29 ATS in road games. 19-26 ATS after playing a home game. 9-15 ATS versus teams who average 9 or more steals/game on the season. 11-6 UNDER as an underdog. 8-4 UNDER off a win against a division rival.

Detroit Pistons: 26-19 1H ATS in home games. 11-6 1H ATS as a home favorite of 6 points or less. 26-19 1H ATS versus good offensive teams - scoring 116+ points/game. 9-1 UNDER in a home game where the total is 210 to 219.5. 23-13 UNDER as a favorite of 3.5 to 9.5 points.

Cleveland Cavaliers:  None.

Detroit Pistons:  K. Huerter (SG) Day To Day - Adductor.

“What a shift, right? Really struggled in the first half and then big-time, second-half performance by Don.” - Kenny Atkinson after his team’s win against the Pistons in the 4th game of this series on Monday. 

"It's unacceptable, it is. We didn't do enough to help ourselves. I'll start there. Ever since we came to Cleveland, the whistle has changed. There's no way one guy on their team has more shots than our team. We can't allow that to be the reason why, because we didn't play well enough. You look at the foul count and the disparity, that's the reason why. Since Kenny made comments about us, since then, the whistle has changed." - J.B. Bickerstaff after his team’s loss against the Cavaliers in game 4 of this series on Monday. 

PG James Harden

SG Donovan Mitchell

SF Dean Wade

PF Evan Mobley

C Jarrett Allen

PG Cade Cunningham

SG Duncan Robinson

SF Ausar Thompson

PF Tobias Harris

C Jalen Duren

PPG: Donovan Mitchell (27.9)

APG: James Harden (7.7)

Reb/G: Evan Mobley (9)

PPG: Cade Cunningham (23.9)

APG: Cade Cunningham (9.9)

Reb/G: Jalen Duren (10.5)

Coaches:

Cleveland Cavaliers: Kenny Atkinson (2nd season)

Detroit Pistons: J.B. Bickerstaff (2nd season)