Cleveland Browns vs Pittsburgh Steelers Prediction, Preview and Odds - 10/12/2025

Game Time: 1:00 pm ET, Sunday, October 12, 2025

Venue:  Acrisure Stadium, Pittsburgh, PA 

Where to Watch:  CBS

DraftKings:  Point Spread:  Browns +4.5, Steelers -4.5; Over/Under:  37.5 points

Bet365:  Point Spread:  Browns +5, Steelers -5; Over/Under:  38 points

BetMGM:  Point Spread:  Browns +5, Steelers -5; Over/Under:  38.5 points

Cleveland Browns:  1-4 (4th place, AFC North)

Pittsburgh Steelers:  3-1 (1st place, AFC North)

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Cleveland Browns:  lost their last game at a neutral site against the Minnesota Vikings 21-17.

Pittsburgh Steelers:  won their last game at a neutral site against the Minnesota Vikings 24-21.

The Browns are entering this game with a 1-4 record overall and they have a 0-2 record in their divisional games too. They are 1-1 in their home games, 0-2 in their road games, and they are also 0-1 in their neutral site games this season, but they will be on the road for this game. They lost their last game against the Minnesota Vikings 21-17. Dillon Gabriel was the starting QB and he completed 19/33 passes for 190 passing yards, 2 touchdowns, and 0 interceptions. Quinshon Judkins led the team in rushing yards with 110. David Njoku led the receivers with 67 receiving yards on 6 receptions and 1 TD. Ronnie Hickman led the defense in that game with 6 solo tackles and 4 assisted tackles while Maliek Collins led the defense in sacks with 2. No one on the defense came away with an interception for them in that one.

 

 

 

The Steelers are entering this game with a 3-1 record overall and they have a 0-0 record in their divisional games too. They are 0-1 in their home games, 2-0 in their road games, and they are also 1-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the Minnesota Vikings 24-21. Aaron Rodgers was the starting QB and he completed 18/22 passes for 200 passing yards, 1 touchdown, and 0 interceptions. Kenneth Gainwell led the team in rushing yards with 99 and 2 TDs. DK Metcalf led the receivers with 126 receiving yards on 5 receptions and 1 TD. Payton Wilson led the defense in that game with 8 solo tackles and 5 assisted tackles while Nick Herbig and Keeanu Benton each led the defense in sacks with 1.5. DeShon Elliott and T. J. Watt each came away with 1 interception for them in that one.

The current betting odds have the Steelers listed as a 4.5 point favorite in this game according to Draftkings Sportsbook. The Steelers have looked good in their games this season with their 3-1 record overall which has them right at the top of the AFC North. Their only loss was to the Seahawks, but they have won 2 games in a row now and they are in a better situation for this game. They are coming out of their bye week so they have had some extra time to prepare for this game and they are catching the Browns in a bad situation too. Meanwhile, the Browns haven't looked great in their games this season with their 1-4 record overall which has them right at the bottom of the AFC North. They are off a 21-17 loss to the Vikings in England and now they are coming back from that game to play on the road against the Steelers here. This isn't a good situation for them coming back from England off a tough loss and with their rookie QB only making his 2nd ever NFL start in a very tough environment. The Browns have had a great defense all season and that defense has been keeping them in their games, but their offense just hasn't been there to match. Even in their last one, they made the change to Dillon Gabriel at QB, but the offense still only put up 17 points. This Steelers defense has looked a lot better in their last 2 games too and they are going to make it very difficult for rookie QB Dillon Gabriel in his 2nd start. The best way to place a bet here is on the Steelers to cover the spread in this game. 

Browns Steelers Prediction:  Our NFL Pick for Sunday, October 12, 2025 (1:00 pm ET start time) is Steelers 21 Browns 13.

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Cleveland Browns: 5-15 ATS in road games. 3-8 ATS vs. bad defensive teams who give up 24 or more points/game. 3-7 ATS vs. poor passing defenses - allowing 7 or more passing yards/att. 14-6 OVER in road games. 10-3 OVER in a road game where the total is between 35.5 and 42 points.

Pittsburgh Steelers: 8-4 ATS in a home game where the total is between 35.5 and 42 points. 9-4 ATS versus division opponents. 8-3 ATS off an upset win as an underdog. 8-4 OVER when playing against a team with a losing record. 3-0 OVER vs. poor offensive teams - scoring 17 or less points/game.

Cleveland Browns:  J. Bitonio (OG) Injured - Rest. M. Corley (WR) Injured - Groin. M. Collins (DL) Injured - Rest. G. Delpit (S) Injured - Ankle. M. Garrett (DL) Injured - Ankle. M. Hall Jr. (DL) Injured - Knee. S. Harris (DL) Injured - Knee. K. Leveston (OT) Injured - Calf. G. Newsome II (CB) Injured - Hamstring. D. Njoku (TE) Injured - Knee. E. Pocic (C) Injured - Neck. D. Ward (CB) Injured - Hip.

Pittsburgh Steelers:  D. Slay (CB) Injured - NIR - Rest. J. Ramsey (CB) Injured - Hamstring. C. Heyward (DL) Injured - NIR - Rest. T. Watt (LB) Injured - NIR - Rest. A. Highsmith (LB) Injured - Ankle. C. Austin III (WR) Injured - Shoulder. B. Skowronek (WR) Injured - Illness. J. Porter Jr. (CB) Injured - Hamstring. J. Warren (RB) Injured - Knee.

“We, as an offense, have to be better and score more to help this football team. But for a young player in that environment versus that defense to take care of the ball, make the plays he made, I thought was a lot of positives with plenty to clean up. That's what he will do, and that's the mentality he has.” - Kevin Stefanski after his team’s loss against the Vikings in their last game. 

"We made it a little bit more entertaining than maybe it should have been, but the Vikings had a lot to do with that." - Mike Tomlin after his team’s win against the Vikings in their last game. 

WR Thrash, Jamari

WR Jeudy, Jerry

WR Bond, Isaiah

TE Njoku, David

QB Gabriel, Dillon

RB Judkins, Quinshon

WR Metcalf, DK

WR Wilson, Roman

TE Smith, Jonnu

TE Freiermuth, Pat 

QB Rodgers, Aaron

RB Gainwell, Kenneth

Passing: Joe Flacco (815)

Rushing: Quinshon Judkins (347)

Receiving: Jerry Jeudy (197)

Touchdowns: Cedric Tillman (2)

Passing: Aaron Rodgers (786)

Rushing: Kenneth Gainwell (154)

Receiving: DK Metcalf (261)

Touchdowns: DK Metcalf (3)

Coaches:

Cleveland Browns: Kevin Stefanski (6th season)

Pittsburgh Steelers: Mike Tomlin (19th season)